PMID- 36252749
OWN - NLM
STAT- MEDLINE
DCOM- 20221206
LR  - 20221212
IS  - 1873-4995 (Electronic)
IS  - 0168-3659 (Linking)
VI  - 352
DP  - 2022 Dec
TI  - Synergistic chemotherapy and phototherapy based on red blood cell biomimetic 
      nanomaterials.
PG  - 146-162
LID - S0168-3659(22)00689-7 [pii]
LID - 10.1016/j.jconrel.2022.10.019 [doi]
AB  - Novel drug delivery systems (DDSs) have become the mainstay of research in 
      targeted cancer therapy. By combining different therapeutic strategies, potential 
      DDSs and synergistic treatment approaches are needed to effectively deal with 
      evolving drug resistance and the adverse effects of cancer. Nowadays, developing 
      and optimizing human cell-based DDSs has become a new research strategy. Among 
      them, red blood cells can be used as DDSs as they significantly enhance the 
      pharmacokinetics of the transported drug cargo. Phototherapy, as a novel adjuvant 
      in cancer treatment, can be divided into photodynamic therapy and photothermal 
      therapy. Phototherapy using erythropoietic nanocarriers to mimic the unique 
      properties of erythrocytes and overcome the limitations of existing DDSs shows 
      excellent prospects in clinical settings. This review provides an overview of the 
      development of photosensitizers and research on bio-nano-delivery systems based 
      on erythrocytes and erythrocyte membranes that are used in achieving synergistic 
      outcomes during phototherapy/chemotherapy.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Meng, Di
AU  - Meng D
AD  - College of Bioengineering, Henan University of Technology, Zhengzhou, PR China.
FAU - Yang, Shuoye
AU  - Yang S
AD  - College of Bioengineering, Henan University of Technology, Zhengzhou, PR China; 
      Key Laboratory of Functional Molecules for Biomedical Research, Zhengzhou, PR 
      China. Electronic address: yangshuoyehaut@163.com.
FAU - Yang, Yanan
AU  - Yang Y
AD  - College of Bioengineering, Henan University of Technology, Zhengzhou, PR China.
FAU - Zhang, Lu
AU  - Zhang L
AD  - College of Bioengineering, Henan University of Technology, Zhengzhou, PR China; 
      Key Laboratory of Functional Molecules for Biomedical Research, Zhengzhou, PR 
      China.
FAU - Cui, Lan
AU  - Cui L
AD  - College of Bioengineering, Henan University of Technology, Zhengzhou, PR China; 
      Key Laboratory of Functional Molecules for Biomedical Research, Zhengzhou, PR 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20221019
PL  - Netherlands
TA  - J Control Release
JT  - Journal of controlled release : official journal of the Controlled Release 
      Society
JID - 8607908
SB  - IM
MH  - Humans
MH  - Biomimetics
MH  - Phototherapy
MH  - Drug Delivery Systems
MH  - *Nanostructures
MH  - *Neoplasms/drug therapy
MH  - Erythrocyte Membrane
MH  - *Nanoparticles/therapeutic use
OTO - NOTNLM
OT  - Drug delivery system
OT  - Erythrocytes
OT  - Photosensitizers
OT  - Phototherapy
OT  - Red blood cells
OT  - Synergistic effect
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/10/18 06:00
MHDA- 2022/12/07 06:00
CRDT- 2022/10/17 19:25
PHST- 2022/07/22 00:00 [received]
PHST- 2022/10/08 00:00 [revised]
PHST- 2022/10/10 00:00 [accepted]
PHST- 2022/10/18 06:00 [pubmed]
PHST- 2022/12/07 06:00 [medline]
PHST- 2022/10/17 19:25 [entrez]
AID - S0168-3659(22)00689-7 [pii]
AID - 10.1016/j.jconrel.2022.10.019 [doi]
PST - ppublish
SO  - J Control Release. 2022 Dec;352:146-162. doi: 10.1016/j.jconrel.2022.10.019. Epub 
      2022 Oct 19.