PMID- 36262033
OWN - NLM
STAT- MEDLINE
DCOM- 20221021
LR  - 20221024
IS  - 1473-2300 (Electronic)
IS  - 0300-0605 (Print)
IS  - 0300-0605 (Linking)
VI  - 50
IP  - 10
DP  - 2022 Oct
TI  - Relationships of ABO and Rhesus blood groups with type 2 diabetes mellitus: a 
      systematic review and meta-analysis.
PG  - 3000605221129547
LID - 10.1177/03000605221129547 [doi]
LID - 03000605221129547
AB  - OBJECTIVES: The susceptibility to type 2 diabetes mellitus (T2DM) has been linked 
      to blood type. We aimed to characterize the relationships of the ABO and Rhesus 
      blood groups with T2DM. METHODS: Literature searches were performed using the 
      Medline, PubMed, Scopus, Cochrane, EMBASE, and Google Scholar databases to 
      identify studies published up to 31 March 2022. The PRISMA guidelines were used 
      for reporting. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were 
      obtained using fixed-effects models. RESULTS: Twenty-six studies of 6870 patients 
      with T2DM and 11,879 controls were identified. Compared with the other ABO 
      groups, people with blood type B were at higher risk of T2DM (OR: 1.30, 95% CI: 
      1.20-1.41), while group O was associated with a lower risk (OR: 0.92, 95% CI: 
      0.86-0.98). There were no significant associations of T2DM with blood types A or 
      AB, or Rh factor. CONCLUSION: Individuals with blood type B are at higher risk of 
      developing T2DM. Therefore, they should be screened for T2DM on a frequent basis 
      and be made aware of the importance of maintaining a balanced diet and regular 
      exercise for the prevention of obesity and T2DM. PROSPERO REGISTRATION NUMBER: 
      CRD42022353945.
FAU - Getawa, Solomon
AU  - Getawa S
AUID- ORCID: 0000-0003-2670-9547
AD  - Department of Hematology and Immunohematology, School of Biomedical and 
      Laboratory Sciences, College of Medicine and Health Sciences, University of 
      Gondar, Gondar, Ethiopia.
FAU - Bayleyegn, Biruk
AU  - Bayleyegn B
AD  - Department of Hematology and Immunohematology, School of Biomedical and 
      Laboratory Sciences, College of Medicine and Health Sciences, University of 
      Gondar, Gondar, Ethiopia.
FAU - Aynalem, Melak
AU  - Aynalem M
AD  - Department of Hematology and Immunohematology, School of Biomedical and 
      Laboratory Sciences, College of Medicine and Health Sciences, University of 
      Gondar, Gondar, Ethiopia.
FAU - Worku, Yilkal Belete
AU  - Worku YB
AD  - Department of Internal Medicine, School of Medicine, College of Medicine and 
      Health Sciences, University of Gondar, Gondar, Ethiopia.
FAU - Adane, Tiruneh
AU  - Adane T
AUID- ORCID: 0000-0001-6597-5755
AD  - Department of Hematology and Immunohematology, School of Biomedical and 
      Laboratory Sciences, College of Medicine and Health Sciences, University of 
      Gondar, Gondar, Ethiopia.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
PL  - England
TA  - J Int Med Res
JT  - The Journal of international medical research
JID - 0346411
RN  - 0 (Rh-Hr Blood-Group System)
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Rh-Hr Blood-Group System
MH  - Exercise
MH  - Obesity/complications
PMC - PMC9585571
OTO - NOTNLM
OT  - ABO blood group
OT  - Rhesus blood group
OT  - Type 2 diabetes mellitus
OT  - association
OT  - heterogeneity
OT  - meta-analysis
OT  - systematic review
COIS- The authors declare that there is no conflict of interest.
EDAT- 2022/10/21 06:00
MHDA- 2022/10/22 06:00
PMCR- 2022/10/19
CRDT- 2022/10/20 01:32
PHST- 2022/10/20 01:32 [entrez]
PHST- 2022/10/21 06:00 [pubmed]
PHST- 2022/10/22 06:00 [medline]
PHST- 2022/10/19 00:00 [pmc-release]
AID - 10.1177_03000605221129547 [pii]
AID - 10.1177/03000605221129547 [doi]
PST - ppublish
SO  - J Int Med Res. 2022 Oct;50(10):3000605221129547. doi: 10.1177/03000605221129547.