PMID- 3626713
OWN - NLM
STAT- MEDLINE
DCOM- 19871015
LR  - 20061115
IS  - 0340-1588 (Print)
IS  - 0340-1588 (Linking)
VI  - 66
IP  - 6
DP  - 1987 Jun
TI  - [Dynamics and significance of immunoglobulin E (IgE) as an immunological 
      parameter in squamous cell carcinomas of the oral cavity and pharynx].
PG  - 316-9
AB  - Disorders of the immune system are supposed to be a factor of tumour 
      pathogenesis. A close correlation of tumour activity and immunoglobulin dynamics 
      (IgE) was described in a number of malignant tumours. In patients with squamous 
      cell carcinomas of the oral cavity, the oropharynx and the hypopharynx (n = 80, 
      male), we investigated IgE level changes in relation to tumour growth during the 
      treatment and follow-up period of 2 years. The study group comprised patients 
      with inactive tumours, active tumours and those with a lethal outcome. Enzyme 
      immunoassays were used for IgE determination. Prior to any type of therapy, mean 
      IgE levels were elevated in all patients showing large interindividual 
      variations. No significant prognostic value could be deduced from pre- and 
      posttreatment levels. However, in patients with tumour recurrences sudden IgE 
      level changes were observed (P less than 5%), as well as drastically decreasing 
      ans low IgE levels in patients with tumour-induced cachexia.
FAU - Mayer, B A
AU  - Mayer BA
FAU - Enzmann, H
AU  - Enzmann H
LA  - ger
PT  - Comparative Study
PT  - English Abstract
PT  - Journal Article
TT  - Dynamik und Bedeutung des Immunglobulins E (IgE) als immunologischer Parameter 
      bei Plattenephithel-Karzinomen der Mundhohle und des Rachens.
PL  - Germany
TA  - Laryngol Rhinol Otol (Stuttg)
JT  - Laryngologie, Rhinologie, Otologie
JID - 7513628
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Carcinoma, Squamous Cell/*diagnosis/therapy
MH  - Combined Modality Therapy
MH  - Follow-Up Studies
MH  - Humans
MH  - Hypopharyngeal Neoplasms/diagnosis/therapy
MH  - Immunoglobulin E/*analysis
MH  - Mouth Neoplasms/*diagnosis/therapy
MH  - Neoplasm Recurrence, Local/diagnosis
MH  - Oropharyngeal Neoplasms/diagnosis/therapy
MH  - Pharyngeal Neoplasms/*diagnosis/therapy
MH  - Prognosis
EDAT- 1987/06/01 00:00
MHDA- 1987/06/01 00:01
CRDT- 1987/06/01 00:00
PHST- 1987/06/01 00:00 [pubmed]
PHST- 1987/06/01 00:01 [medline]
PHST- 1987/06/01 00:00 [entrez]
PST - ppublish
SO  - Laryngol Rhinol Otol (Stuttg). 1987 Jun;66(6):316-9.