PMID- 36284678 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221028 IS - 1671-5411 (Print) IS - 1671-5411 (Linking) VI - 19 IP - 9 DP - 2022 Sep 28 TI - Association between heart failure severity and mobility in geriatric patients: an in-clinic study with wearable sensors. PG - 660-674 LID - 10.11909/j.issn.1671-5411.2022.09.010 [doi] AB - BACKGROUND: Individuals with heart failure (HF) frequently experience limitations in mobility, but specific aspects of these limitations are not well understood. This study investigated the association of HF severity, based on the New York Heart Association (NYHA) classes, with digital mobility outcomes (DMOs) and handgrip strength in older inpatients with HF. METHODS: For this explorative analysis, hospital admission and discharge data from an ongoing, prospective cohort study were used. The sample included older participants with HF and a sub-sample of heart-healthy individuals. Participants were equipped with a wearable inertial measurement unit (IMU) system during mobility performance (balancing, sit-to-stand transfer, walking). We analyzed the association between 17 DMOs and HF severity with multiple linear regression models. RESULTS: The total sample included 61 older participants (65-97 years of age, 55.7% female). Of all DMOs, only sway path in a semi-tandem stance position (m/s(2)) showed a relevant association with NYHA classes (admission: beta = -0.28, P = 0.09; discharge: beta = -0.39, P = 0.02). Handgrip strength showed a trend towards a significant association (admission: beta = -0.15, P = 0.10; discharge: beta = -0.15, P = 0.19). CONCLUSIONS: This is to our best knowledge the first analysis on the association of HF severity and IMU-based DMOs. Sway path and handgrip strength may be the most promising parameters for monitoring mobility aspects in treatment of HF. CI - (c) 2022 JGC All rights reserved; www.jgc301.com. FAU - Braun, Tobias AU - Braun T AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. AD - Department of Applied Health Sciences, Division of Physiotherapy, Hochschule fur Gesundheit (University of Applied Sciences), Gesundheitscampus 6-8, 44801 Bochum, Germany. AD - HSD Hochschule Dopfer (University of Applied Sciences), Waidmarkt 3 und 9, 50676 Cologne, Germany. FAU - Wiegard, Anna AU - Wiegard A AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Geritz, Johanna AU - Geritz J AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Hansen, Clint AU - Hansen C AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Tan, Kim Eng AU - Tan KE AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Hildesheim, Hanna AU - Hildesheim H AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Kudelka, Jennifer AU - Kudelka J AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Maetzler, Corina AU - Maetzler C AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Welzel, Julius AU - Welzel J AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Romijnders, Robbin AU - Romijnders R AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Maetzler, Walter AU - Maetzler W AD - Department of Neurology, Kiel University, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. FAU - Bergmann, Philipp AU - Bergmann P AD - Department of Internal Medicine I, Christian-Albrechts-University of Kiel, Arnold-Heller-Strasse 3, 24105 Kiel, Germany. LA - eng PT - Journal Article PL - China TA - J Geriatr Cardiol JT - Journal of geriatric cardiology : JGC JID - 101237881 PMC - PMC9548060 EDAT- 2022/10/27 06:00 MHDA- 2022/10/27 06:01 PMCR- 2022/09/28 CRDT- 2022/10/26 02:06 PHST- 2022/10/26 02:06 [entrez] PHST- 2022/10/27 06:00 [pubmed] PHST- 2022/10/27 06:01 [medline] PHST- 2022/09/28 00:00 [pmc-release] AID - jgc-19-9-660 [pii] AID - 10.11909/j.issn.1671-5411.2022.09.010 [doi] PST - ppublish SO - J Geriatr Cardiol. 2022 Sep 28;19(9):660-674. doi: 10.11909/j.issn.1671-5411.2022.09.010.