PMID- 3629127 OWN - NLM STAT- MEDLINE DCOM- 19870928 LR - 20151119 IS - 0035-6344 (Print) IS - 0035-6344 (Linking) VI - 57 IP - 1 DP - 1987 Jan-Feb TI - Non-clinical tests for the diagnosis of multiple sclerosis. PG - 33-40 AB - Liquoral, Neurophysiological and Nuclear Imaging data were investigated in 29 patients suffering from Definite (11 cases), Probable (11 cases) and Possible (7 cases) Multiple Sclerosis (MS). The most sensitive tests were: Visual Evoked Potentials (VEPs), altered in 75% of patients, Motor Evoked Potentials (MEPs), abnormal in 75%, Nuclear Magnetic Resonance Imaging (MRI) in 72.4%. Somatosensory Evoked Potentials (SEPs) were altered in 69.2% in PN-SEPs and in 53.6% in MN-SEPs, whilst Brainstem Evoked Potentials (BAEPs) were altered in 30.8% of cases. The results suggest that patients with suspected forms of MS should be submitted, as routine diagnostic protocol, to a battery of EPs, including as a first choice VEPs, MEPs and PN-SEPs. MRI should be performed to confirm a diagnosis not supported by EP data, or for a comprehensive localization of the demyelinating plaques. FAU - Rossini, P M AU - Rossini PM FAU - Caramia, M AU - Caramia M FAU - Lavaroni, F AU - Lavaroni F FAU - Spadaro, M AU - Spadaro M FAU - Floris, R AU - Floris R FAU - Tanfani, G AU - Tanfani G FAU - Zarola, F AU - Zarola F FAU - Traversa, R AU - Traversa R FAU - Marciani, M G AU - Marciani MG FAU - Bernardi, G AU - Bernardi G LA - eng PT - Journal Article PL - Italy TA - Riv Neurol JT - Rivista di neurologia JID - 0413740 SB - IM MH - Adolescent MH - Adult MH - *Evoked Potentials, Visual MH - Female MH - Humans MH - *Immunologic Tests MH - *Magnetic Resonance Spectroscopy MH - Male MH - Middle Aged MH - Multiple Sclerosis/*diagnosis/immunology/physiopathology EDAT- 1987/01/01 00:00 MHDA- 1987/01/01 00:01 CRDT- 1987/01/01 00:00 PHST- 1987/01/01 00:00 [pubmed] PHST- 1987/01/01 00:01 [medline] PHST- 1987/01/01 00:00 [entrez] PST - ppublish SO - Riv Neurol. 1987 Jan-Feb;57(1):33-40.