PMID- 36292217
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221030
IS  - 2075-4418 (Print)
IS  - 2075-4418 (Electronic)
IS  - 2075-4418 (Linking)
VI  - 12
IP  - 10
DP  - 2022 Oct 18
TI  - An Innovative Concept of a 3D-Coded Aperture Imaging System Proposed for Early 
      Breast Cancer Detection.
LID - 10.3390/diagnostics12102529 [doi]
LID - 2529
AB  - Coded Aperture (CA) imaging has recently been used in nuclear medicine, but 
      still, there is no commercial SPECT imaging camera based on CA for cancer 
      detection. The literature is rich in examples of using the CA for planar and thin 
      3D imaging. However, thick 3D reconstruction is still challenging for small 
      lesion detection. This paper presents the results of mosaic modified uniformly 
      redundant array (MURA) mask/antimask CA combined with a maximum-likelihood 
      expectation-maximization (MLEM) algorithm. The MLEM is an iterative algorithm 
      applied to a mosaic MURA CA mask/antimask for 3D anthropomorphic breast phantom 
      reconstruction, slice by slice. The difference between the mask and the antimask 
      suppresses the background noise to enhance the quality of reconstructed images. 
      Furthermore, all reconstructed slices are stacked to form a 3D breast phantom 
      image from single-projection data. The results of phantom reconstruction with 8 
      mm, 6 mm, 4 mm, and 3 mm lesions are presented. Moreover, the proposed SPECT 
      imaging camera can reconstruct a 3D breast phantom from single-projection data of 
      the patient's scanning. To assess the quality of lesions in the reconstructed 
      images, the contrast-to-background ratio (CBR), the peak signal-to-noise ratio 
      (PSNR) and mean square error (MSE) were measured.
FAU - Hussain, Khalid
AU  - Hussain K
AUID- ORCID: 0000-0001-7967-7230
AD  - Department of Computer and Communication System Engineering, Universiti Putra 
      Malaysia, Serdang 43400, Selangor, Malaysia.
FAU - Alnafea, Mohammed A
AU  - Alnafea MA
AUID- ORCID: 0000-0003-3512-6220
AD  - Department of Radiological Sciences, College of Applied Medical Sciences, King 
      Saud University, Riyadh 11433, Saudi Arabia.
FAU - Saripan, M Iqbal
AU  - Saripan MI
AD  - Department of Computer and Communication System Engineering, Universiti Putra 
      Malaysia, Serdang 43400, Selangor, Malaysia.
FAU - Mahboub, Djelloul
AU  - Mahboub D
AD  - Physics Department, University of Hail, Ha'il 81451, Saudi Arabia.
FAU - Mahmud, Rozi
AU  - Mahmud R
AD  - Faculty of Medicine and Sciences, Universiti Putra Malaysia, Serdang 43400, 
      Selangor, Malaysia.
FAU - Wan Adnan, Wan Azizun
AU  - Wan Adnan WA
AD  - Department of Computer and Communication System Engineering, Universiti Putra 
      Malaysia, Serdang 43400, Selangor, Malaysia.
FAU - Xianling, Dong
AU  - Xianling D
AUID- ORCID: 0000-0001-8572-2632
AD  - Department of Biomedical Engineering, Chengde Medical University, Chengde City 
      067050, China.
LA  - eng
GR  - xxxxx/Universiti Putra Malaysia/
GR  - No.5-1/HRD/UESTPI(Batch-V)/1147/2018/HEC/Higher Education Commission/
PT  - Journal Article
DEP - 20221018
PL  - Switzerland
TA  - Diagnostics (Basel)
JT  - Diagnostics (Basel, Switzerland)
JID - 101658402
PMC - PMC9601382
OTO - NOTNLM
OT  - 3D image reconstruction
OT  - anthropomorphic breast phantom
OT  - coded-aperture imaging
OT  - gamma camera
OT  - mask/antimask
OT  - mosaic MURA mask
COIS- The authors declare no conflict of interest.
EDAT- 2022/10/28 06:00
MHDA- 2022/10/28 06:01
PMCR- 2022/10/18
CRDT- 2022/10/27 01:16
PHST- 2022/07/25 00:00 [received]
PHST- 2022/09/03 00:00 [revised]
PHST- 2022/09/12 00:00 [accepted]
PHST- 2022/10/27 01:16 [entrez]
PHST- 2022/10/28 06:00 [pubmed]
PHST- 2022/10/28 06:01 [medline]
PHST- 2022/10/18 00:00 [pmc-release]
AID - diagnostics12102529 [pii]
AID - diagnostics-12-02529 [pii]
AID - 10.3390/diagnostics12102529 [doi]
PST - epublish
SO  - Diagnostics (Basel). 2022 Oct 18;12(10):2529. doi: 10.3390/diagnostics12102529.