PMID- 36292242 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221030 IS - 2075-4418 (Print) IS - 2075-4418 (Electronic) IS - 2075-4418 (Linking) VI - 12 IP - 10 DP - 2022 Oct 20 TI - Ultrasound-Guided Radiofrequency Ablation for Primary Hyperparathyroidism Induced by Multiple Endocrine Neoplasia 1-A Case Report. LID - 10.3390/diagnostics12102553 [doi] LID - 2553 AB - Multiple endocrine neoplasia type 1 (MEN1) is a syndrome characterized by the occurrence of two or more endocrine gland tumors. Here, we show a case of a 52-year-old man diagnosed with MEN1 through gastrinoma, parathyroid adenoma and gene detection. The MEN1 patient's case was complicated with relapsed primary hyperparathyroidism (PHPT), and they received ultrasound-guided radiofrequency ablation (RFA). The patient had a remarkable recovery after RFA treatment for the relapsed PHPT. It might be an alternative treatment for MEN1 patients with poor conditions such as high surgical risk, unwillingness to choose parathyroid surgery or those unable to tolerate surgery. Individualized therapy significantly benefits the prognosis of MEN1 patients. FAU - Han, Zhenping AU - Han Z AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. AD - Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. FAU - Li, Tingting AU - Li T AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. FAU - Wang, Siyi AU - Wang S AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. AD - Department of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China. FAU - Gao, Li AU - Gao L AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. FAU - Hu, Ying AU - Hu Y AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. AD - Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou 310014, China. FAU - Zhao, Yu AU - Zhao Y AD - Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou 310014, China. AD - Department of Endocrinology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. FAU - Yan, Jieping AU - Yan J AD - Center for Clinical Pharmacy, Department of Pharmacy, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, China. AD - Key Laboratory of Endocrine Gland Diseases of Zhejiang Province, Hangzhou 310014, China. LA - eng GR - 81903597/National Natural Science Foundation of China/ GR - LQ16H310003/Zhejiang Provincial Natural Science Foundation/ GR - 2021KY016/Medical and Health Science and Technology Research Program of Zhejiang Province/ GR - 2021KY018/Medical and Health Science and Technology Research Program of Zhejiang Province/ GR - 2019RC096/Medical and Health Science and Technology Research Program of Zhejiang Province/ PT - Journal Article DEP - 20221020 PL - Switzerland TA - Diagnostics (Basel) JT - Diagnostics (Basel, Switzerland) JID - 101658402 PMC - PMC9600646 OTO - NOTNLM OT - multiple endocrine neoplasia type 1 OT - parathyroid OT - primary hyperparathyroidism OT - radiofrequency ablation OT - ultrasound-guided COIS- The authors declare no conflict of interest. EDAT- 2022/10/28 06:00 MHDA- 2022/10/28 06:01 PMCR- 2022/10/20 CRDT- 2022/10/27 01:17 PHST- 2022/09/15 00:00 [received] PHST- 2022/10/13 00:00 [revised] PHST- 2022/10/19 00:00 [accepted] PHST- 2022/10/27 01:17 [entrez] PHST- 2022/10/28 06:00 [pubmed] PHST- 2022/10/28 06:01 [medline] PHST- 2022/10/20 00:00 [pmc-release] AID - diagnostics12102553 [pii] AID - diagnostics-12-02553 [pii] AID - 10.3390/diagnostics12102553 [doi] PST - epublish SO - Diagnostics (Basel). 2022 Oct 20;12(10):2553. doi: 10.3390/diagnostics12102553.