PMID- 36305884
OWN - NLM
STAT- MEDLINE
DCOM- 20221101
LR  - 20231102
IS  - 1536-4801 (Electronic)
IS  - 0277-2116 (Print)
IS  - 0277-2116 (Linking)
VI  - 75
IP  - 5
DP  - 2022 Nov 1
TI  - Pre-endoscopy Symptoms and Age, But Not Esophageal Biopsy Number Are Associated 
      With Post-endoscopy Adverse Events.
PG  - 656-660
LID - 10.1097/MPG.0000000000003594 [doi]
AB  - Esophagogastroduodenoscopy (EGD) is a frequently utilized investigative tool in 
      the management of gastrointestinal conditions in children. Biopsies obtained 
      during EGD may pose risk for post-operative adverse events (AEs), and further 
      understanding of risk is imperative to provide informed consent to families and 
      safe patient care. In particular, the impact of biopsy number and location on the 
      development of AEs has not been studied in pediatric patients. We prospectively 
      assessed for AEs by telephone survey 3-7 days after 209 EGDs performed on 
      patients ages 1-21 years over a 1-year period. Demographic, endoscopic, and 
      histologic data were collected. The most common symptoms reported were throat 
      pain (61%), chest pain (26%), and dysphagia (26%). Binary regression models 
      identified age and pre-operative symptoms as factors that influenced the 
      likelihood of post-operative morbidity. Multiple biopsies from 3 different 
      locations of the esophagus did not impact the risk of post-operative AEs.
CI  - Copyright (c) 2022 by European Society for European Society for Pediatric 
      Gastroenterology, Hepatology, and Nutrition and North American Society for 
      Pediatric Gastroenterology, Hepatology, and Nutrition.
FAU - Wenzel, Amanda A
AU  - Wenzel AA
AD  - From the Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, IL.
FAU - Kagalwalla, Amir F
AU  - Kagalwalla AF
AD  - From the Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, IL.
AD  - the Division of Pediatric Gastroenterology John H Stroger Hospital of Cook 
      County, Chicago, IL.
FAU - Wechsler, Joshua B
AU  - Wechsler JB
AD  - From the Division of Gastroenterology, Hepatology and Nutrition, Ann & Robert H. 
      Lurie Children's Hospital of Chicago, Chicago, IL.
LA  - eng
GR  - K08 DK097721/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20220818
PL  - United States
TA  - J Pediatr Gastroenterol Nutr
JT  - Journal of pediatric gastroenterology and nutrition
JID - 8211545
SB  - IM
MH  - Humans
MH  - Child
MH  - Infant
MH  - Child, Preschool
MH  - Adolescent
MH  - Young Adult
MH  - Adult
MH  - Retrospective Studies
MH  - *Endoscopy, Gastrointestinal
MH  - Biopsy/adverse effects
MH  - Endoscopy, Digestive System/adverse effects
MH  - *Deglutition Disorders/etiology/diagnosis
PMC - PMC9627599
MID - NIHMS1830036
COIS- The authors report no conflicts of interest.
EDAT- 2022/10/29 06:00
MHDA- 2022/11/02 06:00
PMCR- 2023/11/01
CRDT- 2022/10/28 11:12
PHST- 2022/10/28 11:12 [entrez]
PHST- 2022/10/29 06:00 [pubmed]
PHST- 2022/11/02 06:00 [medline]
PHST- 2023/11/01 00:00 [pmc-release]
AID - 00005176-202211000-00020 [pii]
AID - 10.1097/MPG.0000000000003594 [doi]
PST - ppublish
SO  - J Pediatr Gastroenterol Nutr. 2022 Nov 1;75(5):656-660. doi: 
      10.1097/MPG.0000000000003594. Epub 2022 Aug 18.