PMID- 36309156
OWN - NLM
STAT- MEDLINE
DCOM- 20230203
LR  - 20230223
IS  - 1556-3871 (Electronic)
IS  - 1547-5271 (Linking)
VI  - 20
IP  - 2
DP  - 2023 Feb
TI  - Rapid ventricular tachycardia in patients with tetralogy of Fallot and 
      implantable cardioverter-defibrillator: Insights from the DAI-T4F nationwide 
      registry.
PG  - 252-260
LID - S1547-5271(22)02573-5 [pii]
LID - 10.1016/j.hrthm.2022.10.016 [doi]
AB  - BACKGROUND: In repaired tetralogy of Fallot (TOF), little is known about 
      characteristics of patients with rapid ventricular tachycardia (VT). Also, 
      whether patients with a first episode of nonrapid VT may subsequently develop 
      rapid VT or ventricular fibrillation (VF) has not been addressed. OBJECTIVES: The 
      objectives of this study were to compare patients with rapid VT/VF with those 
      with nonrapid VT and to assess the evolution of VT cycle lengths (VTCLs) 
      overtime. METHODS: Data were analyzed from a nationwide registry including all 
      patients with TOF and implantable cardioverter-defibrillator (ICD) since 2000. 
      Patients with >/=1 VT episode with VTCL </=250 ms (240 beats/min) formed the rapid 
      VT/VF group. RESULTS: Of 144 patients (mean age 42.0 +/- 12.7 years; 104 [72%] 
      men), 61 (42%) had at least 1 VT/VF episode, including 28 patients with rapid 
      VT/VF (46%), during a median follow-up of 6.3 years (interquartile range 2.2-10.3 
      years). Compared with patients in the nonrapid VT group, those in the rapid VT/VF 
      group were significantly younger at ICD implantation (35.2 +/- 12.6 years vs 41.5 +/- 
      11.2 years; P = .04), had more frequently a history of cardiac arrest (8 [29%] vs 
      2 [6%]; P = .02), less frequently a history of atrial arrhythmia (11 [42%] vs 22 
      [69%]; P = .004), and higher right ventricular ejection fraction (43.3% +/- 10.3% 
      vs 36.6% +/- 11.2%; P = .04). The median VTCL of VT/VF episodes was 325 ms 
      (interquartile range 235-429 ms). None of the patients with a first documented 
      nonrapid VT episode had rapid VT/VF during follow-up. CONCLUSION: Patients with 
      TOF and rapid VT/VF had distinct clinical characteristics. The relatively low 
      variation of VTCL over time suggests a room for catheter ablation without a 
      backup ICD in selected patients with well-tolerated VT.
CI  - Copyright (c) 2022 Heart Rhythm Society. Published by Elsevier Inc. All rights 
      reserved.
FAU - Laredo, Mikael
AU  - Laredo M
AD  - Unite de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La 
      Pitie-Salpetriere University Hospital, Paris, France.
FAU - Duthoit, Guillaume
AU  - Duthoit G
AD  - Unite de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La 
      Pitie-Salpetriere University Hospital, Paris, France.
FAU - Sacher, Frederic
AU  - Sacher F
AD  - LIRYC Institute, Bordeaux University Hospital, Bordeaux, France.
FAU - Anselme, Frederic
AU  - Anselme F
AD  - Rouen University Hospital, Rouen, France.
FAU - Audinet, Caroline
AU  - Audinet C
AD  - Bretagne Sud Hospital, Lorient, France.
FAU - Bessiere, Francis
AU  - Bessiere F
AD  - Louis Pradel Hospital, Lyon, France.
FAU - Bordachar, Pierre
AU  - Bordachar P
AD  - LIRYC Institute, Bordeaux University Hospital, Bordeaux, France.
FAU - Bouzeman, Abdeslam
AU  - Bouzeman A
AD  - Parly II Private Hospital, Le Chesnay, France.
FAU - Boveda, Serge
AU  - Boveda S
AD  - Pasteur Clinic, Toulouse, France.
FAU - Bun, Sok Sithikun
AU  - Bun SS
AD  - Princess Grace Hospital, Monaco, France.
FAU - Chassignolle, Morgane
AU  - Chassignolle M
AD  - Universite de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France.
FAU - Clerici, Gael
AU  - Clerici G
AD  - Saint Pierre University Hospital, La Reunion, France.
FAU - Da Costa, Antoine
AU  - Da Costa A
AD  - Saint Etienne University Hospital, Saint Etienne, France.
FAU - de Guillebon, Maxime
AU  - de Guillebon M
AD  - Pau Hospital, Pau, France.
FAU - Defaye, Pascal
AU  - Defaye P
AD  - Grenoble University Hospital, Grenoble, France.
FAU - Elbaz, Nathalie
AU  - Elbaz N
AD  - Henri-Mondor University Hospital, Creteil, France.
FAU - Eschalier, Romain
AU  - Eschalier R
AD  - Clermont Ferrand University Hospital, Clermont Ferrand, France.
FAU - Extramiana, Fabrice
AU  - Extramiana F
AD  - Bichat University Hospital, Paris, France.
FAU - Fauchier, Laurent
AU  - Fauchier L
AD  - Tours University Hospital, Tours, France.
FAU - Hermida, Alexis
AU  - Hermida A
AD  - Amiens University Hospital, Amiens, France.
FAU - Gandjbakhch, Estelle
AU  - Gandjbakhch E
AD  - Unite de Rythmologie, Cardiology institute, Sorbonne University, AP-HP, La 
      Pitie-Salpetriere University Hospital, Paris, France.
FAU - Garcia, Rodrigue
AU  - Garcia R
AD  - Poitiers University Hospital, Poitiers, France.
FAU - Gourraud, Jean-Baptiste
AU  - Gourraud JB
AD  - Nantes University Hospital, Nantes, France.
FAU - Guenancia, Charles
AU  - Guenancia C
AD  - Dijon University Hospital, Dijon, France.
FAU - Guy-Moyat, Benoit
AU  - Guy-Moyat B
AD  - Limoges University Hospital, Limoges, France.
FAU - Irles, Didier
AU  - Irles D
AD  - Annecy Hospital, Annecy, France.
FAU - Iserin, Laurence
AU  - Iserin L
AD  - Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou 
      Hospital, Paris, France.
FAU - Jourda, Francois
AU  - Jourda F
AD  - Auxerre Hospital, Auxerre, France.
FAU - Koutbi, Linda
AU  - Koutbi L
AD  - La Timone Hospital, Marseille, France.
FAU - Labombarda, Fabien
AU  - Labombarda F
AD  - Caen University Hospital, Caen, France.
FAU - Ladouceur, Magalie
AU  - Ladouceur M
AD  - Universite de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; 
      Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou 
      Hospital, Paris, France.
FAU - Lagrange, Philippe
AU  - Lagrange P
AD  - Saint-Pierre Clinic, Perpignan, France.
FAU - Lellouche, Nicolas
AU  - Lellouche N
AD  - Henri-Mondor University Hospital, Creteil, France.
FAU - Mansourati, Jacques
AU  - Mansourati J
AD  - Brest University Hospital, Brest, France.
FAU - Marquie, Christelle
AU  - Marquie C
AD  - Lille University Hospital, Lille, France.
FAU - Martins, Raphael
AU  - Martins R
AD  - Rennes University Hospital, Rennes, France.
FAU - Massoulie, Gregoire
AU  - Massoulie G
AD  - Clermont Ferrand University Hospital, Clermont Ferrand, France.
FAU - Mathiron, Amel
AU  - Mathiron A
AD  - Amiens University Hospital, Amiens, France.
FAU - Maury, Philippe
AU  - Maury P
AD  - Toulouse University Hospital, Toulouse, France.
FAU - Messali, Anne
AU  - Messali A
AD  - Bichat University Hospital, Paris, France.
FAU - Milhem, Antoine
AU  - Milhem A
AD  - La Rochelle Hospital, La Rochelle, France.
FAU - Mondoly, Pierre
AU  - Mondoly P
AD  - Toulouse University Hospital, Toulouse, France.
FAU - Nguyen, Cedric
AU  - Nguyen C
AD  - Chalon sur Saone Hospital, Chalon sur Saone, France.
FAU - Ninni, Sandro
AU  - Ninni S
AD  - Lille University Hospital, Lille, France.
FAU - Pasquie, Jean Luc
AU  - Pasquie JL
AD  - Montpellier University Hospital, Montpellier, France.
FAU - Pierre, Bertrand
AU  - Pierre B
AD  - Tours University Hospital, Tours, France.
FAU - Pujadas, Penelope
AU  - Pujadas P
AD  - Les Franciscaines Clinic, Nimes, France.
FAU - Sellal, Jean-Marc
AU  - Sellal JM
AD  - Nancy University Hospital, Nancy, France.
FAU - Thambo, Jean-Benoit
AU  - Thambo JB
AD  - LIRYC Institute, Bordeaux University Hospital, Bordeaux, France.
FAU - Walton, Camille
AU  - Walton C
AD  - Louis Pradel Hospital, Lyon, France.
FAU - Winum, Pierre
AU  - Winum P
AD  - Nimes University Hospital, Nimes, France.
FAU - Zakine, Cyril
AU  - Zakine C
AD  - Saint-Gatien Clinic, Tours, France.
FAU - Zhao, Alexandre
AU  - Zhao A
AD  - Ambroise Pare Clinic, Neuilly, France.
FAU - Jouven, Xavier
AU  - Jouven X
AD  - Universite de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; 
      Cardiac Electrophysiology Section, European Georges Pompidou Hospital, Paris, 
      France.
FAU - Combes, Nicolas
AU  - Combes N
AD  - Pasteur Clinic, Toulouse, France.
FAU - Marijon, Eloi
AU  - Marijon E
AD  - Universite de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; 
      Cardiac Electrophysiology Section, European Georges Pompidou Hospital, Paris, 
      France.
FAU - Waldmann, Victor
AU  - Waldmann V
AD  - Universite de Paris, INSERM, Paris Cardiovascular Research Centre, Paris, France; 
      Adult Congenital Heart Disease Medico-Surgical Unit, European Georges Pompidou 
      Hospital, Paris, France; Cardiac Electrophysiology Section, European Georges 
      Pompidou Hospital, Paris, France. Electronic address: victor.waldmann@gmail.com.
CN  - DAI-T4F Investigators
LA  - eng
SI  - ClinicalTrials.gov/NCT03837574
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20221026
PL  - United States
TA  - Heart Rhythm
JT  - Heart rhythm
JID - 101200317
SB  - IM
MH  - Male
MH  - Humans
MH  - Adult
MH  - Middle Aged
MH  - Female
MH  - *Defibrillators, Implantable
MH  - Stroke Volume
MH  - *Tetralogy of Fallot/complications/surgery
MH  - Follow-Up Studies
MH  - Ventricular Function, Right
MH  - *Tachycardia, Ventricular/epidemiology/etiology/therapy
MH  - Ventricular Fibrillation
OTO - NOTNLM
OT  - Adult congenital heart disease
OT  - Implantable cardioverter-defibrillator
OT  - Rapid ventricular tachycardia
OT  - Sudden cardiac death
OT  - Tetralogy of Fallot
OT  - Ventricular arrhythmia
EDAT- 2022/10/30 06:00
MHDA- 2023/02/04 06:00
CRDT- 2022/10/29 19:25
PHST- 2022/08/29 00:00 [received]
PHST- 2022/09/28 00:00 [revised]
PHST- 2022/10/19 00:00 [accepted]
PHST- 2022/10/30 06:00 [pubmed]
PHST- 2023/02/04 06:00 [medline]
PHST- 2022/10/29 19:25 [entrez]
AID - S1547-5271(22)02573-5 [pii]
AID - 10.1016/j.hrthm.2022.10.016 [doi]
PST - ppublish
SO  - Heart Rhythm. 2023 Feb;20(2):252-260. doi: 10.1016/j.hrthm.2022.10.016. Epub 2022 
      Oct 26.