PMID- 36310074
OWN - NLM
STAT- MEDLINE
DCOM- 20221101
LR  - 20221101
IS  - 1881-7742 (Electronic)
IS  - 0301-4800 (Linking)
VI  - 68
IP  - 5
DP  - 2022
TI  - Association between Dietary Protein Intake and Type 2 Diabetes Mellitus in 
      Chinese Rural Elderly Population: A Matched Case-Control Study.
PG  - 399-408
LID - 10.3177/jnsv.68.399 [doi]
AB  - The purpose of this study was to examine the association between dietary protein 
      intake and the risk of type 2 diabetes mellitus (T2DM) among a Chinese rural 
      elderly population. We used the demographic and dietary information of adults 
      over age 65 in the Henan Rural Cohort Study to identify and pair 950 T2DM 
      patients with healthy controls in a 1 : 1 matched case-control study. Dietary 
      data was collected through a Food Frequency Questionnaire. A multivariate 
      logistic regression model was applied to calculate the odds ratio (OR) and 95% 
      confidence interval (CI) of T2DM risk according to protein intake. After 
      adjustment for confounding factors, higher intake of total protein was negatively 
      associated with T2DM risk in the total population (extreme-tertile OR=0.75, 95% 
      CI: 0.58-0.93) and women (extreme-tertile OR=0.84, 95% CI: 0.47-0.93). 
      Multivariate-adjusted ORs for the risk of T2DM in the highest compared with 
      lowest tertile of plant protein intake in the total population and in women were 
      0.86 (95% CI: 0.60-0.84) and 0.58 (95% CI: 0.36-0.95), respectively. Our results 
      suggest that the protein intake, especially plant protein, has a significant 
      association with the risk of T2DM in rural elderly populations, and the sources 
      of protein may be also important in future guidelines.
FAU - Liang, Qian
AU  - Liang Q
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Lyu, Quanjun
AU  - Lyu Q
AD  - Department of Nutrition, The First Affiliated Hospital of Zhengzhou University.
FAU - Fan, Mengying
AU  - Fan M
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Mao, Zhenxing
AU  - Mao Z
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Wang, Chongjian
AU  - Wang C
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Li, Yuqian
AU  - Li Y
AD  - Department of Clinical Pharmacology, School of Pharmaceutical Science, Zhengzhou 
      University.
FAU - Cui, Songyang
AU  - Cui S
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Niu, Kailin
AU  - Niu K
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Gu, Ruohua
AU  - Gu R
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
FAU - Li, Linlin
AU  - Li L
AD  - Department of Epidemiology and Health Statistics, College of Public Health, 
      Zhengzhou University.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - J Nutr Sci Vitaminol (Tokyo)
JT  - Journal of nutritional science and vitaminology
JID - 0402640
RN  - 0 (Dietary Proteins)
RN  - 0 (Plant Proteins)
SB  - IM
MH  - Adult
MH  - Humans
MH  - Female
MH  - Aged
MH  - *Diabetes Mellitus, Type 2/epidemiology
MH  - Case-Control Studies
MH  - Cohort Studies
MH  - Dietary Proteins
MH  - Risk Factors
MH  - Plant Proteins
MH  - China/epidemiology
OTO - NOTNLM
OT  - T2DM
OT  - case-control study
OT  - dietary protein
OT  - elderly population
OT  - rural China
EDAT- 2022/10/31 06:00
MHDA- 2022/11/02 06:00
CRDT- 2022/10/30 21:43
PHST- 2022/10/30 21:43 [entrez]
PHST- 2022/10/31 06:00 [pubmed]
PHST- 2022/11/02 06:00 [medline]
AID - 10.3177/jnsv.68.399 [doi]
PST - ppublish
SO  - J Nutr Sci Vitaminol (Tokyo). 2022;68(5):399-408. doi: 10.3177/jnsv.68.399.