PMID- 36312673
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221102
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 9
DP  - 2022 Sep
TI  - A Large Inflammatory Myofibroblastic Tumor of the Urinary Bladder in a Parturient 
      Treated by Partial Cystectomy: Case Report and Literature Review.
PG  - e29556
LID - 10.7759/cureus.29556 [doi]
LID - e29556
AB  - Inflammatory myofibroblastic tumor (IMT) is a rare type of tumor composed mainly 
      of fibroblastic and myofibroblastic spindle cells, with an inflammatory 
      infiltrate of lymphocytes, plasma cells, and eosinophils. IMT may arise from 
      different organs and sites, but it is infrequent to arise from the urinary 
      bladder and usually manifests as hematuria. We report a case of a 24-year-old 
      pregnant woman who presented to our hospital with gross hematuria. After further 
      workup, we concluded that she had this extremely rare tumor, which was resected 
      eventually with a partial cystectomy. Although the diagnosis of these kinds of 
      tumors is usually made by anaplastic lymphoma kinase (ALK) using 
      immunohistochemistry and detecting ALK gene translocation using fluorescence in 
      situ hybridization (FISH), they were negative in our study; hence, we relied 
      mainly on the morphological features of the tumor for the diagnosis.
CI  - Copyright (c) 2022, Buksh et al.
FAU - Buksh, Omar
AU  - Buksh O
AD  - Department of Urology, King Faisal Specialist Hospital and Research Centre, 
      Jeddah, SAU.
FAU - Almalki, Abdullah M
AU  - Almalki AM
AD  - Department of Urology, King Faisal Specialist Hospital and Research Centre, 
      Jeddah, SAU.
FAU - Khogeer, Ahmed
AU  - Khogeer A
AD  - Department of Urology, King Faisal Specialist Hospital and Research Centre, 
      Jeddah, SAU.
FAU - Al-Maghrabi, Jaudah
AU  - Al-Maghrabi J
AD  - Department of Pathology, Faculty of Medicine, King Abdulaziz University, Jeddah, 
      SAU.
FAU - Alakraa, Mahmoud
AU  - Alakraa M
AD  - Department of Urology, King Faisal Specialist Hospital and Research Centre, 
      Jeddah, SAU.
LA  - eng
PT  - Case Reports
DEP - 20220925
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9595141
OTO - NOTNLM
OT  - anaplastic lymphoma kinase
OT  - inflammatory myofibroblastic tumor
OT  - myofibroblast
OT  - pseudotumor
OT  - urinary bladder
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/11/01 06:00
MHDA- 2022/11/01 06:01
PMCR- 2022/09/25
CRDT- 2022/10/31 04:42
PHST- 2022/09/25 00:00 [accepted]
PHST- 2022/10/31 04:42 [entrez]
PHST- 2022/11/01 06:00 [pubmed]
PHST- 2022/11/01 06:01 [medline]
PHST- 2022/09/25 00:00 [pmc-release]
AID - 10.7759/cureus.29556 [doi]
PST - epublish
SO  - Cureus. 2022 Sep 25;14(9):e29556. doi: 10.7759/cureus.29556. eCollection 2022 
      Sep.