PMID- 36313461
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221102
IS  - 1664-8021 (Print)
IS  - 1664-8021 (Electronic)
IS  - 1664-8021 (Linking)
VI  - 13
DP  - 2022
TI  - An overview of online resources for intra-species detection of gene duplications.
PG  - 1012788
LID - 10.3389/fgene.2022.1012788 [doi]
LID - 1012788
AB  - Gene duplication plays an important role in evolutionary mechanism, which can act 
      as a new source of genetic material in genome evolution. However, detecting 
      duplicate genes from genomic data can be challenging. Various bioinformatics 
      resources have been developed to identify duplicate genes from single and/or 
      multiple species. Here, we summarize the metrics used to measure sequence 
      identity among gene duplicates within species, compare several computational 
      approaches that have been used to predict gene duplicates, and review recent 
      advancements of a Basic Local Alignment Search Tool (BLAST)-based web tool and 
      database, allowing future researchers to easily identify intra-species gene 
      duplications. This article is a quick reference guide for research tools used for 
      detecting gene duplicates.
CI  - Copyright (c) 2022 Zhang and Smith.
FAU - Zhang, Xi
AU  - Zhang X
AD  - Department of Biochemistry and Molecular Biology, Dalhousie University, Halifax, 
      NS, Canada.
AD  - Institute for Comparative Genomics, Dalhousie University, Halifax, NS, Canada.
FAU - Smith, David Roy
AU  - Smith DR
AD  - Department of Biology, Western University, London, ON, Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20221013
PL  - Switzerland
TA  - Front Genet
JT  - Frontiers in genetics
JID - 101560621
PMC - PMC9606816
OTO - NOTNLM
OT  - comparative genomics
OT  - gene duplication
OT  - genome duplication
OT  - genome evolution
OT  - paralogous genes
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/11/01 06:00
MHDA- 2022/11/01 06:01
PMCR- 2022/10/13
CRDT- 2022/10/31 04:58
PHST- 2022/08/05 00:00 [received]
PHST- 2022/09/20 00:00 [accepted]
PHST- 2022/10/31 04:58 [entrez]
PHST- 2022/11/01 06:00 [pubmed]
PHST- 2022/11/01 06:01 [medline]
PHST- 2022/10/13 00:00 [pmc-release]
AID - 1012788 [pii]
AID - 10.3389/fgene.2022.1012788 [doi]
PST - epublish
SO  - Front Genet. 2022 Oct 13;13:1012788. doi: 10.3389/fgene.2022.1012788. eCollection 
      2022.