PMID- 3632091 OWN - NLM STAT- MEDLINE DCOM- 19871014 LR - 20190514 IS - 0003-4932 (Print) IS - 1528-1140 (Electronic) IS - 0003-4932 (Linking) VI - 206 IP - 3 DP - 1987 Sep TI - Results with the Mustard operation in simple transposition of the great arteries 1963-1985. PG - 251-60 AB - From May 1963 to December 1985, 329 infants and children underwent repair of simple transposition of the great arteries (TGA) using Mustard's technique. To assess improvement, the patients were separated into two groups by date of operation: Group I, May 1963 to December 1973 (N = 106), and Group II, January 1974 to December 1985 (N = 223). The operative mortality was 11 (10.4%) in Group I and two (0.9%) in Group II. The 10-year actuarial survival rate was 73.4% in Group I and 93.7% in Group II. Baffle complications, similar in both groups, were identified in 81 patients; 19 were major, causing death or requiring reoperation. By latest electrocardiogram, 21 of 45 (46.7%) of Group I patients and 129 of 180 (71.7%) of Group II patients were in normal sinus rhythm. Late ambulatory electrocardiography, however, revealed that a majority of patients had sinus node dysfunction or other dysrhythmias. Right ventricular (RV) angiography revealed definite diminution of RV contractility in 14 (11%) of 126 children. At late follow-up, 113 of 148 (76%) children were in New York Heart Association (NYHA) Class I and 35 of 148 (24%) were in NYHA Class II. Thirty-five (21%) patients were on cardiac medication chiefly for dysrhythmia management. There has been significant improvement in the early and late mortality with the Mustard operation, and serious baffle complications are infrequent. Dysrhythmias continue to be a major problem but the surviving patients are clinically well and relatively few have significant RV dysfunction. FAU - Trusler, G A AU - Trusler GA FAU - Williams, W G AU - Williams WG FAU - Duncan, K F AU - Duncan KF FAU - Hesslein, P S AU - Hesslein PS FAU - Benson, L N AU - Benson LN FAU - Freedom, R M AU - Freedom RM FAU - Izukawa, T AU - Izukawa T FAU - Olley, P M AU - Olley PM LA - eng PT - Journal Article PL - United States TA - Ann Surg JT - Annals of surgery JID - 0372354 SB - IM MH - Actuarial Analysis MH - Adolescent MH - Cardiac Catheterization MH - Child MH - Child, Preschool MH - Electrocardiography MH - Follow-Up Studies MH - Heart Ventricles/physiopathology MH - Humans MH - Infant MH - Infant, Newborn MH - Methods MH - Muscle Contraction MH - Postoperative Complications/mortality MH - Transposition of Great Vessels/mortality/physiopathology/*surgery PMC - PMC1493177 EDAT- 1987/09/01 00:00 MHDA- 1987/09/01 00:01 PMCR- 1988/03/01 CRDT- 1987/09/01 00:00 PHST- 1987/09/01 00:00 [pubmed] PHST- 1987/09/01 00:01 [medline] PHST- 1987/09/01 00:00 [entrez] PHST- 1988/03/01 00:00 [pmc-release] AID - 10.1097/00000658-198709000-00003 [doi] PST - ppublish SO - Ann Surg. 1987 Sep;206(3):251-60. doi: 10.1097/00000658-198709000-00003.