PMID- 36321095
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221104
IS  - 2046-2069 (Electronic)
IS  - 2046-2069 (Linking)
VI  - 12
IP  - 46
DP  - 2022 Oct 17
TI  - Au@bovine serum albumin nanoparticle-based acid-resistant nanozyme quartz crystal 
      microbalance sensing of urine glucose.
PG  - 29727-29733
LID - 10.1039/d2ra04707a [doi]
AB  - A robust, efficient and sensitive quartz crystal microbalance (QCM) for glucose 
      detection has been constructed using Au@bovine serum albumin (Au@BSA) 
      nanoparticles as an active layer. The nanoparticles serve as tandem nanozymes and 
      their stability over natural enzymes enable the sensor to show a wider linear 
      dynamic range between 0.05 and 15 mM, a higher acid-resistance (pH 2.0-8.0) and 
      heat-resistance (35-60  degrees C) than conventional glucose oxidase (GOx)-based sensors. 
      The sensor has been further applied to measure glucose content in artificial 
      urine directly without dilution, where the recovery of 99.6-105.2% and the 
      relative standard deviations (RSDs) below 0.88% confirm a good reproducibility 
      for the measurement results. In addition, the developed Au@BSA QCM sensor can 
      retain 95% of its initial activity after 40 days of storage. Overall, the Au@BSA 
      sensor shows better comprehensive performance than the commercial sensor strips 
      for urine glucose analysis and provides a promising approach in a more precise 
      and robust manner.
CI  - This journal is (c) The Royal Society of Chemistry.
FAU - Zhou, Dengfeng
AU  - Zhou D
AUID- ORCID: 0000-0002-9270-9580
AD  - CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS 
      Center for Excellence in Nanoscience, National Center for Nanoscience and 
      Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 PR China 
      chenlan@nanoctr.cn gegl@nanoctr.cn.
AD  - University of Chinese Academy of Sciences Beijing 100049 PR China.
FAU - Song, Wenyao
AU  - Song W
AD  - CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS 
      Center for Excellence in Nanoscience, National Center for Nanoscience and 
      Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 PR China 
      chenlan@nanoctr.cn gegl@nanoctr.cn.
AD  - University of Chinese Academy of Sciences Beijing 100049 PR China.
FAU - Zhang, Shuangbin
AU  - Zhang S
AD  - CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS 
      Center for Excellence in Nanoscience, National Center for Nanoscience and 
      Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 PR China 
      chenlan@nanoctr.cn gegl@nanoctr.cn.
AD  - University of Chinese Academy of Sciences Beijing 100049 PR China.
FAU - Chen, Lan
AU  - Chen L
AUID- ORCID: 0000-0002-7243-5244
AD  - CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS 
      Center for Excellence in Nanoscience, National Center for Nanoscience and 
      Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 PR China 
      chenlan@nanoctr.cn gegl@nanoctr.cn.
FAU - Ge, Guanglu
AU  - Ge G
AUID- ORCID: 0000-0002-2460-6686
AD  - CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS 
      Center for Excellence in Nanoscience, National Center for Nanoscience and 
      Technology No. 11 Zhongguancun Beiyitiao Beijing 100190 PR China 
      chenlan@nanoctr.cn gegl@nanoctr.cn.
LA  - eng
PT  - Journal Article
DEP - 20221017
PL  - England
TA  - RSC Adv
JT  - RSC advances
JID - 101581657
PMC - PMC9575391
COIS- There are no conflicts to declare.
EDAT- 2022/11/03 06:00
MHDA- 2022/11/03 06:01
PMCR- 2022/10/17
CRDT- 2022/11/02 02:23
PHST- 2022/07/28 00:00 [received]
PHST- 2022/10/11 00:00 [accepted]
PHST- 2022/11/02 02:23 [entrez]
PHST- 2022/11/03 06:00 [pubmed]
PHST- 2022/11/03 06:01 [medline]
PHST- 2022/10/17 00:00 [pmc-release]
AID - d2ra04707a [pii]
AID - 10.1039/d2ra04707a [doi]
PST - epublish
SO  - RSC Adv. 2022 Oct 17;12(46):29727-29733. doi: 10.1039/d2ra04707a. eCollection 
      2022 Oct 17.