PMID- 36324694 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221104 IS - 1663-9812 (Print) IS - 1663-9812 (Electronic) IS - 1663-9812 (Linking) VI - 13 DP - 2022 TI - Positive short term effects of an integrative korean medicine treatment package for low back pain caused by motor vehicle accidents: A retrospective chart review of real - world practice data. PG - 1003849 LID - 10.3389/fphar.2022.1003849 [doi] LID - 1003849 AB - Backgrounds No standard treatment exist for reducing symptoms related to sequelae of motor vehicle accidents (MVAs). In Korea, comprehensive Korean Medicine (KM) treatment that includes botanical drugs (herbal medicine), acupuncture, pharmacopuncture, tuina, moxibustion, and cupping is covered by automobile insurance and increasingly used to help alleviate such pain. This study aimed to analyze real-world data and to evaluate the effectiveness and safety of comprehensive KM treatment for low back pain caused by MVAs. Methods We conducted a retrospective chart review of patients who received KM treatment during hospitalization. Records that lacked follow-up outcome assessments were excluded. The Verbal Numerical Rating Scale (VNRS), the Korean version of the Oswestry Disability Index (K-ODI) and the Korean version of the Roland-Morris Disability Questionnaire (K-RMDQ) were evaluated at admission and discharge. Adverse events were also analyzed. A paired t-test was used to identify the effectiveness of KM treatment. Results A total of 50 patients, 30 males and 20 females, were included in the analysis. The mean age of the patients was 40.72 +/- 13.31 years and the average treatment period was 7.22 +/- 3.84 days. After treatment, VNRS, K-ODI and K-RMDQ were significantly improved (p < 0.001). There was a decrease from 5.06 +/- 1.60 to 3.40 +/- 1.81 in VNRS, 33.38 +/- 16.88 to 24.54 +/- 13.63 in K-ODI, and 6.84 +/- 6.27 to 4.14 +/- 4.38 in K-RMDQ. During this period, a total of two adverse events were reported. Discussion Although this retrospective chart review looked into the short term effects only, comprehensive KM treatment might be an effective and safe therapeutic option to reduce acute low back pain especially after MVA. Prospective research data is needed to support this hypothesis. CI - Copyright (c) 2022 Park, Lee, Yoon, Jo, Kim, Kim, Sul and Leem. FAU - Park, Hye-Rin AU - Park HR AD - Chung-Yeon Korean Medicine Hospital, Gwangju, South Korea. FAU - Lee, Seungmin Kathy AU - Lee SK AD - Virginia University of Integrative Medicine, Fairfax, VA, United States. AD - QualTEAM Academy, Seoul, South Korea. FAU - Yoon, Sang-Hoon AU - Yoon SH AD - Chung-Yeon Korean Medicine Clinic, Seoul, South Korea. FAU - Jo, Hee-Geun AU - Jo HG AD - Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, Seongnam, South Korea. FAU - Kim, Ji-Yong AU - Kim JY AD - Jayoenanae Korean Medicine Clinic, Busan, South Korea. FAU - Kim, Hyunho AU - Kim H AD - QualTEAM Academy, Seoul, South Korea. FAU - Sul, Jae-Uk AU - Sul JU AD - Department of Korean Rehabilitation Medicine, Dongshin University Korean Medicine Hospital, Gwangju, South Korea. FAU - Leem, Jungtae AU - Leem J AD - College of Korean Medicine, Wonkwang University, Iksan, South Korea. LA - eng PT - Journal Article DEP - 20221017 PL - Switzerland TA - Front Pharmacol JT - Frontiers in pharmacology JID - 101548923 PMC - PMC9618792 OTO - NOTNLM OT - Korean medicine OT - acupuncture OT - botanical drug OT - herbal medicine OT - integrative medicine OT - low back pain OT - motor vehicle accident OT - real world data COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/11/04 06:00 MHDA- 2022/11/04 06:01 PMCR- 2022/10/17 CRDT- 2022/11/03 02:32 PHST- 2022/07/26 00:00 [received] PHST- 2022/09/29 00:00 [accepted] PHST- 2022/11/03 02:32 [entrez] PHST- 2022/11/04 06:00 [pubmed] PHST- 2022/11/04 06:01 [medline] PHST- 2022/10/17 00:00 [pmc-release] AID - 1003849 [pii] AID - 10.3389/fphar.2022.1003849 [doi] PST - epublish SO - Front Pharmacol. 2022 Oct 17;13:1003849. doi: 10.3389/fphar.2022.1003849. eCollection 2022.