PMID- 36330349
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221105
IS  - 1662-4548 (Print)
IS  - 1662-453X (Electronic)
IS  - 1662-453X (Linking)
VI  - 16
DP  - 2022
TI  - The contribution of the left precuneus to emotion memory in migraine without aura 
      patients.
PG  - 905942
LID - 10.3389/fnins.2022.905942 [doi]
LID - 905942
AB  - BACKGROUND: The impact of migraine without aura (MWoA) on cognitive function 
      remains controversial, especially given the sparse literature on emotional 
      memory. METHODS: Twenty seven MWoA patients and 25 healthy controls (HCs) were 
      enrolled in this cross-sectional study. Emotional memory behavior was evaluated 
      by combining incidental encoding with intentional encoding of five emotional 
      categories of visual stimulus [positive valence + high arousal (PH), negative 
      valence + high arousal (NH), positive valence + low arousal (PL), negative 
      valence + low arousal (NL), and neutral (N)]. The recollection performance (Pr) 
      was measured and compared. Then, the neural relevance was explored by correlating 
      the Pr with gray matter volume (GMV) and resting-state functional connectivity 
      (rs-FC) based on structural and functional magnetic resonance imaging. RESULTS: 
      No significant differences in recollection performance or emotional enhancement 
      of memory effect were observed. However, MWoA patients were more sensitive to the 
      valence and arousal of emotional stimuli under incidental encoding. 
      Significantly, the Pr-PH under incidental encoding and Pr-PL under intentional 
      encoding were negatively correlated with the GMV of the left precuneus, and the 
      rs-FC between the left precuneus and putamen was positively correlated with Pr-PL 
      under intentional encoding in MWoA patients. CONCLUSION: Our study demonstrated 
      the tendency for the influence of migraine on emotional memory and revealed the 
      left precuneus as a critical contributor to recollection performance, providing 
      novel insights for understanding emotional memory and its neural mechanisms in 
      MWoA patients.
CI  - Copyright (c) 2022 Li, Li, Zhu, Zhu, Wang, Gao, Wu, Zhou, Wang and Yu.
FAU - Li, Meiqin
AU  - Li M
AD  - The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
FAU - Li, Xiaoshu
AU  - Li X
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Zhu, Wanqiu
AU  - Zhu W
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Zhu, Jiajia
AU  - Zhu J
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Wang, Haibao
AU  - Wang H
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Gao, Ziwen
AU  - Gao Z
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Wu, Xingqi
AU  - Wu X
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Zhou, Shanshan
AU  - Zhou S
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Wang, Kai
AU  - Wang K
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
FAU - Yu, Yongqiang
AU  - Yu Y
AD  - The First Affiliated Hospital of Anhui Medical University, Hefei, China.
LA  - eng
PT  - Journal Article
DEP - 20221018
PL  - Switzerland
TA  - Front Neurosci
JT  - Frontiers in neuroscience
JID - 101478481
PMC - PMC9624281
OTO - NOTNLM
OT  - emotional memory
OT  - gray matter volume
OT  - magnetic resonance imaging
OT  - migraine without aura
OT  - resting-state functional connectivity
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/11/05 06:00
MHDA- 2022/11/05 06:01
PMCR- 2022/01/01
CRDT- 2022/11/04 02:33
PHST- 2022/03/28 00:00 [received]
PHST- 2022/09/27 00:00 [accepted]
PHST- 2022/11/04 02:33 [entrez]
PHST- 2022/11/05 06:00 [pubmed]
PHST- 2022/11/05 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fnins.2022.905942 [doi]
PST - epublish
SO  - Front Neurosci. 2022 Oct 18;16:905942. doi: 10.3389/fnins.2022.905942. 
      eCollection 2022.