PMID- 36330861
OWN - NLM
STAT- MEDLINE
DCOM- 20221221
LR  - 20221222
IS  - 1879-0003 (Electronic)
IS  - 0141-8130 (Linking)
VI  - 224
DP  - 2023 Jan 1
TI  - Ecofriendly poly(3-hydroxybutyrate-co-4-hydroxybutyrate) microbeads for sanitary 
      products.
PG  - 1487-1495
LID - S0141-8130(22)02492-8 [pii]
LID - 10.1016/j.ijbiomac.2022.10.237 [doi]
AB  - In the past, plastic microbeads (MBs) were added to personal healthcare products 
      to improve the cleaning and exfoliating effects, but these have been withdrawn 
      owing to their non-degradable nature and contribution to the pollution of marine 
      environment, especially that caused by the adsorption of persistent organic 
      pollutants (POPs) on MBs. Therefore, natural biodegradable alternatives are being 
      developed, but these often do not exhibit sufficient performance to replace 
      non-degradable MBs. In this study, poly(3-hydroxybutyrate-co-4-hydroxybutyrate) 
      (P3HB-4HB), a biodegradable aliphatic polyester, was used to prepare MBs via 
      melt-electrospraying. We carried out the rheological characterization of P3HB-4HB 
      with respect to melting temperature, and the melt-electrospray process was 
      optimized to prepare MBs having sizes similar to those of commercially available 
      MBs. Furthermore, the adsorption properties of the P3HB-4HB MBs for POPs were 
      investigated. Unlike commercial MBs, the P3HB-4HB MBs adsorbed significantly 
      fewer contaminants owing to their smooth and regular surfaces. Finally, a 
      cleansing product containing P3HB-4HB MBs was prepared to evaluate their cleaning 
      ability, and we found that the MB-based product could remove dirt and 
      contaminants that were not easily removed by water alone. Thus, the biodegradable 
      P3HB-4HB MBs have great potential for use as sustainable additives for cosmetic 
      products for skin exfoliation.
CI  - Copyright (c) 2022 Elsevier B.V. All rights reserved.
FAU - Choi, Yun Hyeok
AU  - Choi YH
AD  - Department of Organic Materials Engineering, Chungnam National University, 
      Daejeon 34134, South Korea.
FAU - Park, Jeong Jin
AU  - Park JJ
AD  - Department of Organic Materials Engineering, Chungnam National University, 
      Daejeon 34134, South Korea.
FAU - Sim, Eun Jung
AU  - Sim EJ
AD  - CJ Cheiljedang Corp., Suwon-si, Gyeonggi-do 16495, South Korea.
FAU - Lee, Eunhye
AU  - Lee E
AD  - CJ Cheiljedang Corp., Suwon-si, Gyeonggi-do 16495, South Korea.
FAU - Yoon, Ki Chull
AU  - Yoon KC
AD  - CJ Cheiljedang Corp., Suwon-si, Gyeonggi-do 16495, South Korea.
FAU - Park, Won Ho
AU  - Park WH
AD  - Department of Organic Materials Engineering, Chungnam National University, 
      Daejeon 34134, South Korea. Electronic address: parkwh@cnu.ac.kr.
LA  - eng
PT  - Journal Article
DEP - 20221028
PL  - Netherlands
TA  - Int J Biol Macromol
JT  - International journal of biological macromolecules
JID - 7909578
RN  - TZP1275679 (3-Hydroxybutyric Acid)
RN  - 0 (Hydroxybutyrates)
RN  - 117068-64-1 (poly(3-hydroxybutyrate-co-4-hydroxybutyrate))
RN  - 0 (Polyesters)
SB  - IM
MH  - 3-Hydroxybutyric Acid
MH  - *Hydroxybutyrates
MH  - Microspheres
MH  - *Polyesters
OTO - NOTNLM
OT  - Biodegradable microbead
OT  - Cosmetic additive
OT  - Melt-electrospray
OT  - Persistent organic pollutant
OT  - Poly(3-hydroxybutyrate-co-4-hydroxybutyrate)
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/11/05 06:00
MHDA- 2022/12/22 06:00
CRDT- 2022/11/04 05:44
PHST- 2022/09/06 00:00 [received]
PHST- 2022/10/24 00:00 [revised]
PHST- 2022/10/26 00:00 [accepted]
PHST- 2022/11/05 06:00 [pubmed]
PHST- 2022/12/22 06:00 [medline]
PHST- 2022/11/04 05:44 [entrez]
AID - S0141-8130(22)02492-8 [pii]
AID - 10.1016/j.ijbiomac.2022.10.237 [doi]
PST - ppublish
SO  - Int J Biol Macromol. 2023 Jan 1;224:1487-1495. doi: 
      10.1016/j.ijbiomac.2022.10.237. Epub 2022 Oct 28.