PMID- 36332731
OWN - NLM
STAT- MEDLINE
DCOM- 20221207
LR  - 20221207
IS  - 1879-1298 (Electronic)
IS  - 0045-6535 (Linking)
VI  - 312
IP  - Pt 1
DP  - 2023 Jan
TI  - Advanced throughput analytical strategies for the comprehensive HRMS screening of 
      organic micropollutants in eggs of different bird species.
PG  - 137092
LID - S0045-6535(22)03585-8 [pii]
LID - 10.1016/j.chemosphere.2022.137092 [doi]
AB  - Raptors are ideal indicators for biomonitoring studies using wildlife in order to 
      assess the environmental pollution in the terrestrial ecosystem, since they are 
      placed in the highest trophic position in the food webs and their life expectancy 
      is relatively long. In this study, 26 eggs of 4 bird species (Peregrine falcon, 
      Eurasian curlew, Little owl and Eagle owl) collected in Germany, were 
      investigated for the presence of persistent organic pollutants (POPs) and 
      thousands of contaminants of emerging concern (CECs). Generic sample preparation 
      protocols were followed for the extraction of the analytes and the purification 
      of the extracts, and the samples were analyzed both by liquid (LC) and gas 
      chromatography (GC) coupled to high resolution mass spectrometry (HRMS), for 
      capturing a wide range of organic micropollutants with different physicochemical 
      properties. State-of-the-art screening methodologies were applied in the acquired 
      HRMS data, including wide-scope target analysis of 2448 known pollutants and 
      suspect screening of over 65,000 environmentally relevant compounds. Overall, 58 
      pollutants from different chemical classes, such as plant protection products, 
      per- and polyfluoroalkyl substances and medicinal products, as well as their 
      transformation products, were determined through target analysis. Most of the 
      detected compounds were lipophilic (logP>2), although the presence of (semi)polar 
      contaminants should not be overlooked, underlying the need for holistic 
      analytical approaches in environmental monitoring studies. p,p'-DDE, PCB 153 and 
      PCB138, PFOS and methylparaben were the most frequently detected compounds. 50 
      additional substances were identified and semi-quantified through suspect 
      screening workflows, including mainly compounds of industrial use with high 
      production volume.
CI  - Copyright (c) 2022 Elsevier Ltd. All rights reserved.
FAU - Gkotsis, Georgios
AU  - Gkotsis G
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece.
FAU - Nika, Maria-Christina
AU  - Nika MC
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece. Electronic address: nikamar@chem.uoa.gr.
FAU - Athanasopoulou, Antonia I
AU  - Athanasopoulou AI
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece.
FAU - Vasilatos, Konstantinos
AU  - Vasilatos K
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece.
FAU - Alygizakis, Nikiforos
AU  - Alygizakis N
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece; Environmental Institute s.r.o., Okruzna 784/42, 97241, 
      Kos, Slovak Republic.
FAU - Boschert, Martin
AU  - Boschert M
AD  - Bioplan Buhl, Nelkenstr. 10, 77815 Buhl, Germany.
FAU - Osterauer, Raphaela
AU  - Osterauer R
AD  - State Institute for Environment Baden-Wuerttemberg (LUBW), Griesbachstr. 1, 76185 
      Karlsruhe, Germany.
FAU - Hopker, Kai-Achim
AU  - Hopker KA
AD  - State Institute for Environment Baden-Wuerttemberg (LUBW), Griesbachstr. 1, 76185 
      Karlsruhe, Germany.
FAU - Thomaidis, Nikolaos S
AU  - Thomaidis NS
AD  - National and Kapodistrian University of Athens, Panepistimiopolis Zographou, 
      15771, Athens, Greece. Electronic address: ntho@chem.uoa.gr.
LA  - eng
PT  - Journal Article
DEP - 20221101
PL  - England
TA  - Chemosphere
JT  - Chemosphere
JID - 0320657
RN  - 0 (Environmental Pollutants)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Ecosystem
MH  - Gas Chromatography-Mass Spectrometry
MH  - Environmental Monitoring/methods
MH  - *Environmental Pollutants/analysis
MH  - Mass Spectrometry
MH  - Birds
MH  - *Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Contaminants of emerging concern
OT  - High resolution mass spectrometry
OT  - Persistent organic pollutants
OT  - Raptors
OT  - Suspect screening
OT  - Wide-scope target analysis
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/11/05 06:00
MHDA- 2023/02/25 06:00
CRDT- 2022/11/04 20:26
PHST- 2022/06/15 00:00 [received]
PHST- 2022/10/11 00:00 [revised]
PHST- 2022/10/30 00:00 [accepted]
PHST- 2022/11/05 06:00 [pubmed]
PHST- 2023/02/25 06:00 [medline]
PHST- 2022/11/04 20:26 [entrez]
AID - S0045-6535(22)03585-8 [pii]
AID - 10.1016/j.chemosphere.2022.137092 [doi]
PST - ppublish
SO  - Chemosphere. 2023 Jan;312(Pt 1):137092. doi: 10.1016/j.chemosphere.2022.137092. 
      Epub 2022 Nov 1.