PMID- 36334716 OWN - NLM STAT- MEDLINE DCOM- 20230103 LR - 20230111 IS - 1878-8769 (Electronic) IS - 1878-8750 (Linking) VI - 169 DP - 2023 Jan TI - Pain Interference Influence on Postoperative Clinical Trajectory in Patients Undergoing Lumbar Decompression. PG - e270-e278 LID - S1878-8750(22)01539-X [pii] LID - 10.1016/j.wneu.2022.10.122 [doi] AB - OBJECTIVE: Newer Patient-Reported Outcomes (PROs) may offer benefits over legacy PROs in ease of administration and interpretation. We aim to study the influence of preoperative pain interference (PI) using the Patient-Reported Outcomes Measurement Information System (PROMIS) Pain Interference (PROMIS-PI) on postoperative clinical outcomes in patients undergoing lumbar decompression. METHODS: Patients undergoing lumbar decompression without fusion were separated into 2 cohorts: PROMIS-PI < 64 (lesser PI) and PROMIS-PI >/= 64 (greater PI). PROs included PROMIS physical function, PROMIS anxiety (PROMIS-A), PROMIS sleep disturbance (PROMIS-SD), PROMIS-PI, Patient Health Questionnaire-9, Visual Analog Scale (VAS) back, VAS leg, and Oswestry Disability Index (ODI) and were collected at preoperative and postoperative time points. Demographics, perioperative characteristics, PROs, and Minimum Clinically Important Difference (MCID) were compared among groups through non-parametric inferential statistics. RESULTS: One-hundred and seven patients were identified. Independent of preoperative PI, patients reported significant postoperative improvement in PROMIS physical function, PROMIS-A, PROMIS-PI, VAS back, VAS leg, and ODI. The greater PI cohort reported significant postoperative improvement in Patient Health Questionnaire-9 and PROMIS-SD. The lesser PI cohort reported superior preoperative PROs in all domains. Postoperatively, the lesser PI cohort reported superior 6-week PROMIS-A and PROMIS-SD. MCID achievement rates were higher in the greater PI cohort for PROMIS-PI, VAS back, VAS leg, and ODI. CONCLUSIONS: Patients with lower preoperative PI reported superior postoperative anxiety and sleep disturbance. Patients with greater preoperative PI had higher MCID achievement rates in PI, pain, and disability. Patients with greater preoperative PI undergoing lumbar decompression may demonstrate higher rates of clinically tangible improvement. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Nie, James W AU - Nie JW AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Hartman, Timothy J AU - Hartman TJ AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Oyetayo, Omolabake O AU - Oyetayo OO AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - MacGregor, Keith R AU - MacGregor KR AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Zheng, Eileen AU - Zheng E AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. FAU - Singh, Kern AU - Singh K AD - Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, USA. Electronic address: kern.singh@rushortho.com. LA - eng PT - Journal Article DEP - 20221109 PL - United States TA - World Neurosurg JT - World neurosurgery JID - 101528275 SB - IM MH - Humans MH - *Lumbar Vertebrae/surgery MH - Lumbosacral Region/surgery MH - Postoperative Period MH - Patient Reported Outcome Measures MH - *Spinal Fusion/adverse effects MH - Pain/etiology MH - Decompression MH - Treatment Outcome OTO - NOTNLM OT - Lumbar decompression OT - MCID OT - PROs OT - Pain EDAT- 2022/11/06 06:00 MHDA- 2023/01/04 06:00 CRDT- 2022/11/05 20:24 PHST- 2022/09/26 00:00 [received] PHST- 2022/10/30 00:00 [revised] PHST- 2022/10/31 00:00 [accepted] PHST- 2022/11/06 06:00 [pubmed] PHST- 2023/01/04 06:00 [medline] PHST- 2022/11/05 20:24 [entrez] AID - S1878-8750(22)01539-X [pii] AID - 10.1016/j.wneu.2022.10.122 [doi] PST - ppublish SO - World Neurosurg. 2023 Jan;169:e270-e278. doi: 10.1016/j.wneu.2022.10.122. Epub 2022 Nov 9.