PMID- 36339383
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221108
IS  - 0972-124X (Print)
IS  - 0975-1580 (Electronic)
IS  - 0972-124X (Linking)
VI  - 26
IP  - 5
DP  - 2022 Sep-Oct
TI  - Serum Vitamin D level and its association with red blood cell indices in patients 
      with periodontitis.
PG  - 446-450
LID - 10.4103/jisp.jisp_443_21 [doi]
AB  - BACKGROUND: Research of late has brought to light a connect between Vitamin D and 
      anemia. The level of 25hydroxyvitamin D (25(OH) D) is decreased in periodontitis 
      subjects as against subjects without periodontitis and this reduced level could 
      be related to more risk for anemia in periodontitis patients. OBJECTIVE: This 
      study aimed to evaluate the serum 25(OH) D levels and red blood cell indices in 
      patients affected by generalized Stage III Grade B periodontitis and healthy 
      controls and to assess the association between level of Vitamin D and red cell 
      indices in periodontitis patients. MATERIALS AND METHODS: The subjects were 
      categorized into (i) case and (ii) control group of 30 each. Clinical parameters 
      including oral hygiene index simplified, mean ratio of sites that bled on 
      probing, gingival index, probing pocket depth, and the clinical attachment loss 
      were assessed in both the groups. Subjects' blood samples (venous) were taken for 
      the biochemical analysis. RESULTS: In contradiction to healthy subjects, 
      periodontitis subjects had significantly diminished 25(OH) D levels, hemoglobin 
      (Hb), hematocrit, and mean corpuscular hemoglobin concentration (MCHC). 25(OH) D 
      was moderately correlated with MCHC (r = 0.53) and it was statistically 
      significant (P = 0.002). CONCLUSION: Periodontitis impacts Vitamin D status which 
      further causes anemia. It suggests that effective management of periodontitis can 
      help maintain sufficient Vitamin D status and may be vital in preventing anemia.
CI  - Copyright: (c) 2022 Indian Society of Periodontology.
FAU - Gupta, Vineeta
AU  - Gupta V
AD  - Department of Periodontics, Government Dental College and Hospital, Raipur, 
      Chhattisgarh, India.
FAU - Mishra, Supriya
AU  - Mishra S
AD  - Department of Periodontics, Government Dental College and Hospital, Raipur, 
      Chhattisgarh, India.
FAU - Gazala, M P
AU  - Gazala MP
AD  - Department of Periodontics, Government Dental College and Hospital, Raipur, 
      Chhattisgarh, India.
FAU - Vandana, Kharidhi Laxman
AU  - Vandana KL
AD  - Department of Periodontics, Government Dental College and Hospital, Raipur, 
      Chhattisgarh, India.
FAU - Ratre, Madhu Singh
AU  - Ratre MS
AD  - Department of Periodontics, College of Dental Sciences, Davangere, Karnataka, 
      India.
LA  - eng
PT  - Journal Article
DEP - 20220901
PL  - India
TA  - J Indian Soc Periodontol
JT  - Journal of Indian Society of Periodontology
JID - 101499342
PMC - PMC9626783
OTO - NOTNLM
OT  - Anemia
OT  - Vitamin D
OT  - mean corpuscular hemoglobin concentration
OT  - periodontitis
OT  - red blood cell indices
COIS- There are no conflicts of interest.
EDAT- 2022/11/08 06:00
MHDA- 2022/11/08 06:01
PMCR- 2022/09/01
CRDT- 2022/11/07 04:44
PHST- 2021/07/04 00:00 [received]
PHST- 2022/01/10 00:00 [revised]
PHST- 2022/01/15 00:00 [accepted]
PHST- 2022/11/07 04:44 [entrez]
PHST- 2022/11/08 06:00 [pubmed]
PHST- 2022/11/08 06:01 [medline]
PHST- 2022/09/01 00:00 [pmc-release]
AID - JISP-26-446 [pii]
AID - 10.4103/jisp.jisp_443_21 [doi]
PST - ppublish
SO  - J Indian Soc Periodontol. 2022 Sep-Oct;26(5):446-450. doi: 
      10.4103/jisp.jisp_443_21. Epub 2022 Sep 1.