PMID- 36340113
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221108
IS  - 2470-1343 (Electronic)
IS  - 2470-1343 (Linking)
VI  - 7
IP  - 43
DP  - 2022 Nov 1
TI  - Iron Trichloride-Mediated Cascade Reaction of Aminosugar Derivatives for the 
      Synthesis of Fused Tetrahydroisoquinoline-Tetrahydrofuran Systems.
PG  - 39061-39070
LID - 10.1021/acsomega.2c04804 [doi]
AB  - A method to obtain tetrahydroisoquinolines (THIQs) fused to tetrahydrofuran rings 
      from aminosugar derivatives has been developed. The procedure relies on a key 
      deprotection of benzyl ethers followed by a double-cyclization sequence, using 
      FeCl(3) as the sole reagent. This tandem reaction affords the construction of 
      novel fused polycyclic heterocycles with total stereochemical control.
CI  - (c) 2022 The Authors. Published by American Chemical Society.
FAU - Rodriguez-Alvarez, Sandra
AU  - Rodriguez-Alvarez S
AUID- ORCID: 0000-0002-5755-0674
AD  - Departamento de Quimica Organica, Universidad de La Laguna, Avenida Astrofisico 
      Francisco Sanchez, 2, 38206 La Laguna, Tenerife, Spain.
FAU - Palazon, Jose M
AU  - Palazon JM
AUID- ORCID: 0000-0002-5963-4652
AD  - Departamento de Quimica Organica, Universidad de La Laguna, Avenida Astrofisico 
      Francisco Sanchez, 2, 38206 La Laguna, Tenerife, Spain.
FAU - Dorta, Rosa L
AU  - Dorta RL
AUID- ORCID: 0000-0002-4565-0301
AD  - Departamento de Quimica Organica, Universidad de La Laguna, Avenida Astrofisico 
      Francisco Sanchez, 2, 38206 La Laguna, Tenerife, Spain.
LA  - eng
PT  - Journal Article
DEP - 20221017
PL  - United States
TA  - ACS Omega
JT  - ACS omega
JID - 101691658
PMC - PMC9631894
COIS- The authors declare no competing financial interest.
EDAT- 2022/11/08 06:00
MHDA- 2022/11/08 06:01
PMCR- 2022/10/17
CRDT- 2022/11/07 04:56
PHST- 2022/07/29 00:00 [received]
PHST- 2022/09/12 00:00 [accepted]
PHST- 2022/11/07 04:56 [entrez]
PHST- 2022/11/08 06:00 [pubmed]
PHST- 2022/11/08 06:01 [medline]
PHST- 2022/10/17 00:00 [pmc-release]
AID - 10.1021/acsomega.2c04804 [doi]
PST - epublish
SO  - ACS Omega. 2022 Oct 17;7(43):39061-39070. doi: 10.1021/acsomega.2c04804. 
      eCollection 2022 Nov 1.