PMID- 36340523
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221108
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 9
DP  - 2022 Sep
TI  - World Health Organization Versus Diabetes in Pregnancy Study Group India 
      Approaches in the Screening of Gestational Diabetes Among Pregnant Women With 
      Risk Factors: A Study Among Rural Population of Telangana, South India.
PG  - e29799
LID - 10.7759/cureus.29799 [doi]
LID - e29799
AB  - Background Gestational diabetes mellitus (GDM) represents a pathological 
      condition wherein pregnant women (PW) suffer from glycemic dysregulation, which 
      predisposes them to an increased risk of developing complications related to 
      pregnancy and childbirth. The most commonly used guidelines to screen for GDM 
      include those provided by the World Health Organization (WHO), the American 
      Congress of Obstetricians and Gynecologists, the Canadian Diabetes Association, 
      and the International Association of Diabetes and Pregnancy Study Group. The 
      Diabetes in Pregnancy Study Group India (DIPSI) guidelines are national-level 
      recommendations to screen for GDM in India. This study aimed to compare the 
      efficacy of DIPSI criteria versus the WHO guidelines in screening for GDM among 
      the rural population of Telangana, South India Methods A total of 300 PW aged 
      19-35 years with a gestational age of 24-28 weeks attending the antenatal clinic 
      attached to Mahavir Institute of Medical Sciences (MIMS), Vikarabad, Telangana, 
      India were included in the study. The study was approved by the Institutional 
      Ethics Committee of MIMS, and informed consent was obtained from all the 
      participants. Of the 300 subjects included, 75 PW were categorized as at-risk for 
      GDM based on risk factors and were included for further analysis. The data 
      relating to body mass index (BMI), oral glucose tolerance test, and the diagnosis 
      of GDM based on DIPSI and the WHO criteria were collected. Results Out of the 75 
      PW included in the study, an overall GDM prevalence of 32% was noted among 
      which 20 (26.7%) were diagnosed using the WHO criteria, 12 (16%) by DIPSI 
      criteria, and the remaining 73.3% were non-GDM women. The mean gestational age 
      and BMI among non-GDM and GDM patients were 24.74+/-4.15 weeks, 22.24+/-3.60 kg/m(2), 
      and 25.70+/-4.40, 24.48+/-3.37 kg/m(2) (p<0.01), respectively. The activities of 
      glucose at the second hour after a GTT among non-GDM and GDM cases were 
      113.70+/-20.4 mg/dL and 128.04+/-18.6 mg/dL (p=0.004), respectively.  Conclusion 
      DIPSI criteria could identify fewer numbers of GDM women as compared to the WHO 
      criteria. Although the DIPSI criteria are convenient and prescribe less number of 
      interventions, they could possibly miss many cases of GDM. Moreover, PW who 
      remain undiagnosed could, in the future, be at risk of developing diabetes. Based 
      on the study results and because risks should outweigh the benefits, we propose 
      that DIPSI cannot be implemented as a single criterion to screen for GDM among PW 
      in Indian settings.
CI  - Copyright (c) 2022, Jabeen et al.
FAU - Jabeen, Ayesha
AU  - Jabeen A
AD  - Biochemistry, Mahavir Institute of Medical Sciences, Hyderabad, IND.
FAU - Rahman Amberina, Amtul
AU  - Rahman Amberina A
AD  - Biochemistry, Mahavir Institute of Medical Sciences, Hyderabad, IND.
FAU - Sreedhrala, Ahlad
AU  - Sreedhrala A
AD  - Biochemistry, Mahavir Institute of Medical Sciences, Hyderabad, IND.
FAU - Mummareddi, Dinesh Eshwar
AU  - Mummareddi DE
AD  - Biochemistry, Mahavir Institute of Medical Sciences, Hyderabad, IND.
FAU - Begum, Gulam Saidunnisa
AU  - Begum GS
AD  - Biochemistry, College of Medicine and Health Sciences, Sohar, OMN.
LA  - eng
PT  - Journal Article
DEP - 20220930
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9622028
OTO - NOTNLM
OT  - diabetes in pregnancy study group india (dipsi)
OT  - diagnose
OT  - gestational diabetes mellitus
OT  - oral glucose tolerance test
OT  - pregnant women
OT  - rural population
OT  - world health organization (who)
COIS- The Indian Council of Medical Research (ICMR) ShortTerm Research Studentship 
      (STS) program was awarded to MBBS student Ahlad Sreedhrala (Reference ID: 
      2018-03016)
EDAT- 2022/11/08 06:00
MHDA- 2022/11/08 06:01
PMCR- 2022/09/30
CRDT- 2022/11/07 05:02
PHST- 2022/09/30 00:00 [accepted]
PHST- 2022/11/07 05:02 [entrez]
PHST- 2022/11/08 06:00 [pubmed]
PHST- 2022/11/08 06:01 [medline]
PHST- 2022/09/30 00:00 [pmc-release]
AID - 10.7759/cureus.29799 [doi]
PST - epublish
SO  - Cureus. 2022 Sep 30;14(9):e29799. doi: 10.7759/cureus.29799. eCollection 2022 
      Sep.