PMID- 36347073
OWN - NLM
STAT- MEDLINE
DCOM- 20221129
LR  - 20221129
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1685
DP  - 2022 Dec 6
TI  - Magnetic solid phase extraction coupled with high-performance liquid 
      chromatography-diode array detection based on assembled magnetic covalent organic 
      frameworks for selective extraction and detection of microcystins in aquatic 
      foods.
PG  - 463614
LID - S0021-9673(22)00805-6 [pii]
LID - 10.1016/j.chroma.2022.463614 [doi]
AB  - It is crucially important to develop simple, selective, and rapid extraction 
      pretreatments and analytical methods to detect microcystins (MCs) in food samples 
      with complex matrices. In this study, a magnetic self-assembled covalent organic 
      framework (COF) adsorbent was synthesized via a facile approach by using a 
      one-pot reaction of 1,6-bis(4-formylphenyl)-3,8-bis(4-aminophenyl)pyrene (BFBAPy) 
      as precursors to assemble amino-functionalized magnetic Fe(3)O(4)-NH(2) 
      nanoparticles (Fe(3)O(4)@Py-COF, simplified as mCOF). The superparamagnetic mCOF 
      is found to exhibit a high specific surface area, abundant nanopores and good 
      stability. In particular, adsorption experiments demonstrate that mCOF exhibits a 
      good adsorption capability, efficiency and some specificity to MCs. The mCOF was 
      applied for magnetic solid phase extraction (MSPE) of two kinds of MCs (MC-LR and 
      MC-RR) from aquatic samples followed by high-performance liquid 
      chromatography-diode array detection (HPLC-DAD). Under the optimized conditions, 
      good linearity is obtained in the range of 10-1000 microg/kg (R(2)>/=0.9989), the 
      limits of detection are 3.0-4.5 microg/kg, and the relative standard deviations 
      (RSDs) are lower than 4.9% (n=5). The extraction recoveries are also satisfactory 
      (84.2%-105%). These results demonstrate that the developed method can be used as 
      a good alternative method for the selective determination of MCs in complex 
      aquatic foods.
CI  - Copyright (c) 2022. Published by Elsevier B.V.
FAU - Wang, Tianliang
AU  - Wang T
AD  - Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang 
      Province, School of Material Science and Chemical Engineering, Ningbo University, 
      Ningbo 315211, PR China.
FAU - Xie, Hongzhen
AU  - Xie H
AD  - Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang 
      Province, School of Material Science and Chemical Engineering, Ningbo University, 
      Ningbo 315211, PR China.
FAU - Cao, Yuting
AU  - Cao Y
AD  - Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang 
      Province, School of Material Science and Chemical Engineering, Ningbo University, 
      Ningbo 315211, PR China.
FAU - Xu, Qing
AU  - Xu Q
AD  - Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang 
      Province, School of Material Science and Chemical Engineering, Ningbo University, 
      Ningbo 315211, PR China. Electronic address: xuqing@nbu.edu.cn.
FAU - Gan, Ning
AU  - Gan N
AD  - Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang 
      Province, School of Material Science and Chemical Engineering, Ningbo University, 
      Ningbo 315211, PR China. Electronic address: ganning@nbu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20221029
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Metal-Organic Frameworks)
RN  - 0 (Microcystins)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - *Metal-Organic Frameworks
MH  - Microcystins/analysis
MH  - Solid Phase Extraction/methods
MH  - Adsorption
MH  - Magnetic Phenomena
MH  - Limit of Detection
OTO - NOTNLM
OT  - Aquatic foods
OT  - HPLC-DAD
OT  - Magnetic covalent organic frameworks
OT  - Magnetic solid phase extraction
OT  - Microcystin
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/11/09 06:00
MHDA- 2022/11/30 06:00
CRDT- 2022/11/08 18:15
PHST- 2022/08/18 00:00 [received]
PHST- 2022/10/25 00:00 [revised]
PHST- 2022/10/27 00:00 [accepted]
PHST- 2022/11/09 06:00 [pubmed]
PHST- 2022/11/30 06:00 [medline]
PHST- 2022/11/08 18:15 [entrez]
AID - S0021-9673(22)00805-6 [pii]
AID - 10.1016/j.chroma.2022.463614 [doi]
PST - ppublish
SO  - J Chromatogr A. 2022 Dec 6;1685:463614. doi: 10.1016/j.chroma.2022.463614. Epub 
      2022 Oct 29.