PMID- 36352288 OWN - NLM STAT- MEDLINE DCOM- 20230124 LR - 20230201 IS - 1573-6628 (Electronic) IS - 1092-7875 (Print) IS - 1092-7875 (Linking) VI - 27 IP - 1 DP - 2023 Jan TI - Interpregnancy Interval and Child Health Outcomes in India: Evidence from Three Recent Rounds of National Family Health Survey. PG - 126-141 LID - 10.1007/s10995-022-03559-3 [doi] AB - INTRODUCTION: Short interpregnancy interval (IPI) is a well-known risk factor for preterm births and low birth weights. However, research on the association between interpregnancy interval (IPI) and health outcomes in children under age 5 is limited in India. We examined the associations between IPI and five child health outcomes in India. METHODS: We used nationally representative cross-sectional data from three rounds of National Family Health Survey (NFHS) conducted in India during 2005-06, 2015-16 and 2019-21 to examine the associations between IPI [categorized as < 12 months, 12-17 months, 18-23 months (ref), 24-35 months, and 36-59 months] and five child health outcomes - neonatal mortality, postneonatal mortality, diarrhea and/or acute respiratory infections (ARI), stunting, and underweight, for the total sample and, secondarily, using sex-stratified analyses. We used multivariable and mother fixed-effects binary logistic regressions to examine the associations. RESULTS: 3% and 2% of infants died during the neonatal and postneonatal period, respectively. Thirteen, 40, and 37% of children had diarrhea and/or ARI, were stunted, and were underweight, respectively. IPI < 12 months was associated with higher odds of diarrhea and/or ARI (OR: 1.11; 95% CI: 1.05-1.18), stunting (OR: 1.13; 95% CI: 1.08-1.18) and underweight (OR: 1.06; 95% CI: 1.01-1.11). Mother fixed-effects adjustments confirmed these associations and also found that births with IPI of 12-17 months and 36-59 months had higher odds of stunting, and IPI of 12-17 months was also associated with higher odds of underweight. DISCUSSION: Our findings indicate that IPIs shorter than 12 months are a risk factor for diarrhea and/or ARI, and IPIs shorter than 12 months and 12-17 months are risk factors for stunting and underweight among children under 5 in India. Mother fixed-effects models allowed us to adjust our estimates for unobserved heterogeneity; this has rarely been done before. Increases in birth spacing may improve child health outcomes in India. CI - (c) 2022. The Author(s). FAU - Kannaujiya, Ajit Kumar AU - Kannaujiya AK AUID- ORCID: 0000-0002-8075-6136 AD - International Institute for Population Sciences, Mumbai, India. ajeetatbhu@gmail.com. FAU - Kumar, Kaushalendra AU - Kumar K AD - Department of Public Health & Mortality Studies, International Institute for Population Sciences, Mumbai, India. FAU - McDougal, Lotus AU - McDougal L AD - Center on Gender Equity and Health, University of California, San Diego, USA. FAU - Upadhyay, Ashish Kumar AU - Upadhyay AK AD - GENDER Project, International Institute for Population Sciences, Mumbai, India. FAU - Raj, Anita AU - Raj A AD - Center on Gender Equity and Health, University of California, San Diego, USA. FAU - James, K S AU - James KS AD - International Institute for Population Sciences, Mumbai, India. FAU - Singh, Abhishek AU - Singh A AD - Department of Public Health & Mortality Studies, International Institute for Population Sciences, Mumbai, India. LA - eng GR - OPP1179208/Bill and Melinda Gates Foundation/ PT - Journal Article DEP - 20221109 PL - United States TA - Matern Child Health J JT - Maternal and child health journal JID - 9715672 SB - IM MH - Infant, Newborn MH - Infant MH - Female MH - Humans MH - Child MH - Child, Preschool MH - *Birth Intervals MH - Cross-Sectional Studies MH - *Thinness MH - Risk Factors MH - Growth Disorders MH - India/epidemiology MH - Diarrhea/epidemiology MH - Outcome Assessment, Health Care MH - Health Surveys PMC - PMC9867668 OTO - NOTNLM OT - India OT - diarrhea and/or acute respiratory infections OT - interpregnancy interval OT - mother fixed-effects OT - neonatal mortality OT - postneonatal mortality OT - stunting OT - underweight COIS- The authors declare that they have no conflict of interest. EDAT- 2022/11/10 06:00 MHDA- 2023/01/25 06:00 PMCR- 2022/11/09 CRDT- 2022/11/09 23:58 PHST- 2022/09/12 00:00 [accepted] PHST- 2022/11/10 06:00 [pubmed] PHST- 2023/01/25 06:00 [medline] PHST- 2022/11/09 23:58 [entrez] PHST- 2022/11/09 00:00 [pmc-release] AID - 10.1007/s10995-022-03559-3 [pii] AID - 3559 [pii] AID - 10.1007/s10995-022-03559-3 [doi] PST - ppublish SO - Matern Child Health J. 2023 Jan;27(1):126-141. doi: 10.1007/s10995-022-03559-3. Epub 2022 Nov 9.