PMID- 36362489
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230308
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 11
IP  - 21
DP  - 2022 Oct 24
TI  - Doll Therapy Intervention Reduces Challenging Behaviours of Women with Dementia 
      Living in Nursing Homes: Results from a Randomized Single-Blind Controlled Trial.
LID - 10.3390/jcm11216262 [doi]
LID - 6262
AB  - Background: Doll therapy (DT) is a non-pharmacological intervention for the 
      treatment of the behavioural and psychological symptoms of dementia (BPSD). We 
      designed a single-blind randomized controlled trial of the 30-day efficacy of DT 
      in reducing the BPSD, professional caregivers' distress and patients' biomarkers 
      of stress, and in improving the exploration and caregiving behaviours. Methods: 
      We randomly assigned 134 women with moderate-to-severe dementia living in nursing 
      homes (NHs) to a DT intervention (DTI, 67) or a sham intervention with a cube 
      (SI, 67). Results: From the first to the 30th session, the DTI group showed a 
      significant decrease in the Neuropsychiatric Inventory-NH (NPI-NH) total score 
      and in the NPI-NH-Distress score compared to the SI group (both p < 0.001). We 
      observed a greater interest in the doll than in the cube, a greater acceptance of 
      a separation from the nurse among DTI participants, and caregiving and 
      exploratory behaviours towards the doll. There were no differences between the 
      groups in the stress biomarkers. Conclusions: Consistent with attachment theory, 
      our findings support the 30-day efficacy of DT, as this non-pharmacological 
      intervention promotes perceptions of security by creating a situation in which 
      patients feel confident and engaged in a caregiving relationship with the doll 
      and reduces the challenging behaviours that are stressful for professional 
      caregivers.
FAU - Molteni, Valentina
AU  - Molteni V
AD  - Dipartimento di Economia Aziendale e Socio Sanitaria (SUPSI), Centro Competenza 
      Anziani, 6928 Manno, Switzerland.
AD  - GINCO Ticino Association, 6802 Monteceneri, Switzerland.
FAU - Vaccaro, Roberta
AU  - Vaccaro R
AUID- ORCID: 0000-0003-1124-6105
AD  - GINCO Ticino Association, 6802 Monteceneri, Switzerland.
AD  - Golgi Cenci Foundation, 20081 Abbiategrasso, Italy.
FAU - Ballabio, Roberta
AU  - Ballabio R
AD  - Dipartimento di Economia Aziendale e Socio Sanitaria (SUPSI), Centro Competenza 
      Anziani, 6928 Manno, Switzerland.
AD  - GINCO Ticino Association, 6802 Monteceneri, Switzerland.
FAU - Ceppi, Laura
AU  - Ceppi L
AD  - GINCO Ticino Association, 6802 Monteceneri, Switzerland.
AD  - School of Cognitive Therapy, 22100 Como, Italy.
FAU - Cantu, Marco
AU  - Cantu M
AD  - Ente Ospedaliero Cantonale, Istituto di Medicina di Laboratorio (EOLAB), 6500 
      Bellinzona, Switzerland.
FAU - Ardito, Rita B
AU  - Ardito RB
AD  - Department of Psychology, University of Turin, 10124 Turin, Italy.
FAU - Adenzato, Mauro
AU  - Adenzato M
AUID- ORCID: 0000-0002-6997-9283
AD  - Department of Psychology, University of Turin, 10124 Turin, Italy.
FAU - Poletti, Barbara
AU  - Poletti B
AD  - Laboratory of Neuroscience, Department of Neurology, Istituto Auxologico 
      Italiano, IRCCS, 20149 Milan, Italy.
FAU - Guaita, Antonio
AU  - Guaita A
AUID- ORCID: 0000-0003-3954-5932
AD  - Golgi Cenci Foundation, 20081 Abbiategrasso, Italy.
FAU - Pezzati, Rita
AU  - Pezzati R
AD  - Dipartimento di Economia Aziendale e Socio Sanitaria (SUPSI), Centro Competenza 
      Anziani, 6928 Manno, Switzerland.
AD  - GINCO Ticino Association, 6802 Monteceneri, Switzerland.
AD  - School of Cognitive Therapy, 22100 Como, Italy.
LA  - eng
GR  - SUPSI (Manno, Switzerland)/
GR  - School of Cognitive Psychotherapy, Como, Italy/
GR  - Alzheimer Switzerland Association, Berna, Switzerland/
GR  - Foundation for the Study of Neurodegenerative Diseases of Adults and the Elderly, 
      Lugano, Switzerland/
GR  - Fondazione Pica Alfieri, Lugano, Switzerland/
GR  - Alzheimer Switzerland Association Section of Canton Ticino, Lugano, Switzerland/
GR  - Riziero Rezzonico Foundation, Lugano, Switzerland/
GR  - Fondazione Fidinam, Lugano, Switzerland/
GR  - Golgi Cenci Foundation, Abbiategrasso, Italy/
GR  - University of Turin, Italy/
PT  - Journal Article
DEP - 20221024
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC9654994
OTO - NOTNLM
OT  - attachment
OT  - biomarkers of stress
OT  - caregivers
OT  - challenging behaviours
OT  - dementia
OT  - doll therapy
OT  - non-pharmacological therapies
COIS- The authors declare no conflict of interest.
EDAT- 2022/11/12 06:00
MHDA- 2022/11/12 06:01
PMCR- 2022/10/24
CRDT- 2022/11/11 01:30
PHST- 2022/09/14 00:00 [received]
PHST- 2022/10/17 00:00 [revised]
PHST- 2022/10/20 00:00 [accepted]
PHST- 2022/11/11 01:30 [entrez]
PHST- 2022/11/12 06:00 [pubmed]
PHST- 2022/11/12 06:01 [medline]
PHST- 2022/10/24 00:00 [pmc-release]
AID - jcm11216262 [pii]
AID - jcm-11-06262 [pii]
AID - 10.3390/jcm11216262 [doi]
PST - epublish
SO  - J Clin Med. 2022 Oct 24;11(21):6262. doi: 10.3390/jcm11216262.