PMID- 36364839
OWN - NLM
STAT- MEDLINE
DCOM- 20221114
LR  - 20230308
IS  - 2072-6643 (Electronic)
IS  - 2072-6643 (Linking)
VI  - 14
IP  - 21
DP  - 2022 Oct 31
TI  - The Effect of Dietary Patterns on Inflammatory Biomarkers in Adults with Type 2 
      Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled 
      Trials.
LID - 10.3390/nu14214577 [doi]
LID - 4577
AB  - Some evidence supports the fact that chronic low-grade inflammation contributes 
      to the physiopathology of type 2 diabetes mellitus (T2DM), and circulating 
      markers of inflammation (e.g., C-reactive protein (CRP), pro- and 
      anti-inflammatory biomarkers (e.g., adiponectin), and endothelial function 
      markers could indicate an ongoing pathology. Following certain dietary patterns 
      (DPs) may result in favorable changes in inflammatory biomarkers. The overarching 
      aim of this systematic review and meta-analysis is to explore the inflammatory 
      effect of healthy DPs on inflammatory biomarkers in adults with T2DM. A 
      systematic search of the literature was conducted using the electronic databases 
      MEDLINE, SCOPUS, and Cochrane Central Register of Controlled Trials. A total of 
      10 randomized controlled clinical trials (RCTs) were analyzed. In our linear 
      meta-analysis, the random-effects model was applied to estimate standardized mean 
      differences (SMD) to associate the effect of the interventions. Dietary 
      Approaches to Stop Hypertension (DASH), Diabetes UK healthy eating, Mediterranean 
      Diet (MD), Diabetes Prevention Program (DPP), and the American Heart 
      Association's Therapeutic Lifestyle Changes diet were associated with a 
      significant reduction in CRP (SMD: -0.83, 99% CI -1.49, -0.17, p < 0.001; I2 
      94%), while plasma levels of adiponectin were significantly higher with the 
      intake of MD, DPP, and Diabetes UK healthy eating (SMD: 0.81, 99% CI 0.06,1.56, p 
      < 0.005; I2 96%), both of which indicate less inflammation. Sensitivity analyses 
      were carried out, and potential publication bias was examined. In conclusion, 
      low- moderate-quality evidence from RCTs suggests that, for the DPs evaluated, 
      there are favorable changes in CRP and adiponectin.
FAU - Sanchez-Rosales, Abril I
AU  - Sanchez-Rosales AI
AD  - Faculty of Medicine, Universidad Autonoma del Estado de Mexico, Toluca 50180, 
      Mexico.
FAU - Guadarrama-Lopez, Ana L
AU  - Guadarrama-Lopez AL
AD  - Multidisciplinary Clinic of Health, Universidad Autonoma del Estado de Mexico, 
      Toluca 50180, Mexico.
FAU - Gaona-Valle, Laura S
AU  - Gaona-Valle LS
AD  - Centro Medico Lic. Adolfo Lopez Mateos, Instituto de Salud del Estado de Mexico 
      (ISEM), Toluca 50010, Mexico.
FAU - Martinez-Carrillo, Beatriz E
AU  - Martinez-Carrillo BE
AD  - Faculty of Medicine, Universidad Autonoma del Estado de Mexico, Toluca 50180, 
      Mexico.
FAU - Valdes-Ramos, Roxana
AU  - Valdes-Ramos R
AUID- ORCID: 0000-0003-0093-886X
AD  - Faculty of Medicine, Universidad Autonoma del Estado de Mexico, Toluca 50180, 
      Mexico.
LA  - eng
GR  - 3843/2014C/Universidad Autonoma del Estado de Mexico/
GR  - 212946/WT_/Wellcome Trust/United Kingdom
GR  - Fellowship for Doctoral Studies. Abril Iliana Sanches Rosales/Consejo Nacional de 
      Ciencia y Tecnologia/
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20221031
PL  - Switzerland
TA  - Nutrients
JT  - Nutrients
JID - 101521595
RN  - 0 (Adiponectin)
RN  - 0 (Biomarkers)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Adult
MH  - Humans
MH  - *Adiponectin
MH  - Randomized Controlled Trials as Topic
MH  - *Diabetes Mellitus, Type 2
MH  - Biomarkers
MH  - C-Reactive Protein/metabolism
MH  - Inflammation
PMC - PMC9654560
OTO - NOTNLM
OT  - Mediterranean Diet
OT  - biomarkers of inflammation
OT  - chronic inflammation
OT  - dietary patterns
OT  - type 2 diabetes mellitus
COIS- The authors declare no conflict of interest.
EDAT- 2022/11/12 06:00
MHDA- 2022/11/15 06:00
PMCR- 2022/10/31
CRDT- 2022/11/11 01:45
PHST- 2022/08/30 00:00 [received]
PHST- 2022/10/06 00:00 [revised]
PHST- 2022/10/26 00:00 [accepted]
PHST- 2022/11/11 01:45 [entrez]
PHST- 2022/11/12 06:00 [pubmed]
PHST- 2022/11/15 06:00 [medline]
PHST- 2022/10/31 00:00 [pmc-release]
AID - nu14214577 [pii]
AID - nutrients-14-04577 [pii]
AID - 10.3390/nu14214577 [doi]
PST - epublish
SO  - Nutrients. 2022 Oct 31;14(21):4577. doi: 10.3390/nu14214577.