PMID- 36365361
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221117
IS  - 2223-7747 (Print)
IS  - 2223-7747 (Electronic)
IS  - 2223-7747 (Linking)
VI  - 11
IP  - 21
DP  - 2022 Oct 29
TI  - L-Aspartate and L-Glutamine Inhibit Beta-Aminobutyric Acid-Induced Resistance in 
      Tomatoes.
LID - 10.3390/plants11212908 [doi]
LID - 2908
AB  - Plant diseases caused by pathogens lead to economic and agricultural losses, 
      while plant resistance is defined by robustness and timing of defence response. 
      Exposure to microbial-associated molecular patterns or specific chemical 
      compounds can promote plants into a primed state with more robust defence 
      responses. beta-aminobutyric acid (BABA) is an endogenous stress metabolite that 
      induces resistance, thereby protecting various plants' diverse stresses by 
      induction of non-canonical activity after binding into aspartyl-tRNA synthetase 
      (AspRS). In this study, by integrating BABA-induced changes in selected 
      metabolites and transcript data, we describe the molecular processes involved in 
      BABA-induced resistance (BABA-IR) in tomatoes. BABA significantly restricted the 
      growth of the pathogens P. syringae pv. tomato DC3000 and was related to the 
      accumulation of transcripts for pathogenesis-related proteins and jasmonic acid 
      signalling but not salicylic acid signalling in Arabidopsis. The resistance was 
      considerably reduced by applying amino acids L-Asp and L-Gln when L-Gln prevents 
      general amino acid inhibition in plants. Analysis of amino acid changes suggests 
      that BABA-IR inhibition by L-Asp is due to its rapid metabolisation to L-Gln and 
      not its competition with BABA for the aspartyl-tRNA synthetase (AspRS) binding 
      site. Our results showed differences between the effect of BABA on tomatoes and 
      other model plants. They highlighted the importance of comparative studies 
      between plants of agronomic interest subjected to treatment with BABA.
FAU - Janotik, Adam
AU  - Janotik A
AD  - Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic.
FAU - Dadakova, Katerina
AU  - Dadakova K
AUID- ORCID: 0000-0003-0252-5110
AD  - Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic.
FAU - Lochman, Jan
AU  - Lochman J
AUID- ORCID: 0000-0003-4420-8842
AD  - Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic.
FAU - Zapletalova, Martina
AU  - Zapletalova M
AUID- ORCID: 0000-0003-3118-2647
AD  - Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic.
LA  - eng
PT  - Journal Article
DEP - 20221029
PL  - Switzerland
TA  - Plants (Basel)
JT  - Plants (Basel, Switzerland)
JID - 101596181
PMC - PMC9655027
OTO - NOTNLM
OT  - BABA-induced resistance
OT  - Pseudomonas syringae
OT  - amino acids
OT  - jasmonic acid
OT  - beta-aminobutyric acid
COIS- The authors declare no conflict of interest.
EDAT- 2022/11/12 06:00
MHDA- 2022/11/12 06:01
PMCR- 2022/10/29
CRDT- 2022/11/11 01:48
PHST- 2022/09/20 00:00 [received]
PHST- 2022/10/09 00:00 [revised]
PHST- 2022/10/27 00:00 [accepted]
PHST- 2022/11/11 01:48 [entrez]
PHST- 2022/11/12 06:00 [pubmed]
PHST- 2022/11/12 06:01 [medline]
PHST- 2022/10/29 00:00 [pmc-release]
AID - plants11212908 [pii]
AID - plants-11-02908 [pii]
AID - 10.3390/plants11212908 [doi]
PST - epublish
SO  - Plants (Basel). 2022 Oct 29;11(21):2908. doi: 10.3390/plants11212908.