PMID- 36366979
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240503
IS  - 2192-5682 (Print)
IS  - 2192-5682 (Linking)
VI  - 14
IP  - 4
DP  - 2024 May
TI  - What Preoperative Factors Are Associated With Achieving a Clinically Meaningful 
      Improvement and Satisfaction After Single-Level Transforaminal Lumbar Interbody 
      Fusion for Degenerative Spondylolisthesis?
PG  - 1287-1295
LID - 10.1177/21925682221139816 [doi]
AB  - STUDY DESIGN: Prospective cohort study. OBJECTIVES: The purpose of this study was 
      to identify preoperative factors associated with clinically meaningful 
      improvement, patient satisfaction and expectation fulfilment at 2 years follow-up 
      in patients undergoing single-level TLIF for degenerative spondylolisthesis. 
      METHODS: Patients who underwent a primary, single-level TLIF for degenerative 
      spondylolisthesis between 2006 and 2015 were identified from a prospectively 
      maintained institutional spine registry. Baseline characteristics and PROMs 
      including the Oswestry Disability Index (ODI), 36-Item Short-Form Physical 
      Component Score (SF-36 PCS), Mental Component Score (SF-36 MCS), Visual Analogue 
      Scale (VAS) back pain, and VAS leg pain were collected preoperatively, at 
      1 month, 3 months, 6 months, and 2 years. RESULTS: A total of 997 patients were 
      included. Multivariate analyses showed that increasing age (OR 1.039, P < .001) 
      and better preoperative ODI (OR .984, P = .018) were associated with achieving 
      minimal clinically important difference (MCID) for VAS Back. Increasing age (OR 
      1.032, P = .007) and better preoperative VAS Back (OR .783, P < .001) were 
      associated with achieving MCID for VAS Leg. Lower BMI (OR .952, P = .024) and 
      better preoperative ODI (OR .976, P < .001) were associated with achieving MCID 
      for SF-36 PCS. Importantly, a better preoperative SF-36 MCS was associated with 
      MCID attainment for ODI (OR 1.038, P < .001), satisfaction (OR 1.034, P < .001) 
      and expectation fulfilment (OR 1.024, P < .001). CONCLUSION: Patients who were 
      older, have less preoperative disability and better preoperative mental health 
      were significantly more likely to attain clinically meaningful improvement in 
      PROMs and postoperative satisfaction after single-level TLIF. Identification of 
      these factors would aid surgeons in patient selection and surgical counselling 
      for single-level TLIF.
FAU - Moorthy, Vikaesh
AU  - Moorthy V
AUID- ORCID: 0000-0002-5503-5687
AD  - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. 
      RINGGOLD: 37581
FAU - Goh, Graham S
AU  - Goh GS
AUID- ORCID: 0000-0002-7337-3321
AD  - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. 
      RINGGOLD: 37581
FAU - Cheong Soh, Reuben Chee
AU  - Cheong Soh RC
AD  - Department of Orthopaedic Surgery, Singapore General Hospital, Singapore. 
      RINGGOLD: 37581
LA  - eng
PT  - Journal Article
DEP - 20221111
PL  - England
TA  - Global Spine J
JT  - Global spine journal
JID - 101596156
OTO - NOTNLM
OT  - lumbar fusion
OT  - lumbar spine
OT  - minimal clinically important difference
OT  - outcomes
OT  - satisfaction
COIS- Declaration of Conflicting InterestsThe author(s) declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2022/11/12 06:00
MHDA- 2022/11/12 06:01
CRDT- 2022/11/11 04:03
PHST- 2022/11/12 06:01 [medline]
PHST- 2022/11/12 06:00 [pubmed]
PHST- 2022/11/11 04:03 [entrez]
AID - 10.1177/21925682221139816 [doi]
PST - ppublish
SO  - Global Spine J. 2024 May;14(4):1287-1295. doi: 10.1177/21925682221139816. Epub 
      2022 Nov 11.