PMID- 36372738
OWN - NLM
STAT- Publisher
LR  - 20240216
IS  - 2191-0308 (Electronic)
IS  - 0048-7554 (Linking)
DP  - 2022 Nov 14
TI  - Ochratoxin A in coffee and coffee-based products: a global systematic review, 
      meta-analysis, and probabilistic risk assessment.
LID - 10.1515/reveh-2022-0115 [doi]
AB  - Contamination of food with mycotoxins can pose harmful effects on the health of 
      consumers in the long term. Coffee contamination with mycotoxins has become 
      a global concern. This study attempted to meta-analyze the concentration and 
      prevalence of ochratoxin A (OTA) in coffee products and estimate consumers' 
      health risks. The search was conducted among international databases, including 
      Scopus, PubMed, Embase, and Web of Science, for 1 January 2010 to 1 May 2022. The 
      concentration and prevalence of OTA in coffee products were meta-analyzed 
      according to country subgroups. Health risk assessment was conducted based on 
      Margin of Exposures (MOEs) using the Monte Carlo simulation (MCS) technique. The 
      three countries that had the highest Pooled concentration of OTA in coffee were 
      observed in Chile (100.00%), Kuwait (100.00%), and France (100.00%). The overall 
      prevalence of OTA in coffee products was 58.01%, 95% CI (48.37-67.39). The three 
      countries that had the highest concentration of OTA were Philippines 
      (39.55 mug/kg) > Turkey (39.32 mug/kg) > and Panama (21.33 mug/kg). The mean of MOEs 
      in the adult consumers in Panama (9,526) and the Philippines (8,873) was lower 
      than 10,000, while the mean of MOEs in other countries was higher than 10,000. 
      Therefore, monitoring and control plans should be carried out in different 
      countries.
CI  - (c) 2022 Walter de Gruyter GmbH, Berlin/Boston.
FAU - Fakhri, Yadolah
AU  - Fakhri Y
AD  - Food Health Research Center, Hormozgan University of Medical Sciences, Bandar 
      Abbas, Iran.
FAU - Mahdavi, Vahideh
AU  - Mahdavi V
AD  - Iranian Research Institute of Plant Protection, Agricultural Research, Education 
      and Extension Organization (AREEO), Tehran, Iran.
FAU - Ranaei, Vahid
AU  - Ranaei V
AD  - School of Health, Arak University of Medical Sciences, Arak, Iran.
FAU - Pilevar, Zahra
AU  - Pilevar Z
AD  - School of Health, Arak University of Medical Sciences, Arak, Iran.
FAU - Sarafraz, Mansour
AU  - Sarafraz M
AD  - School of Public Health, Shahroud University of Medical Sciences, Shahroud, Iran.
FAU - Mahmudiono, Trias
AU  - Mahmudiono T
AD  - Department of Nutrition, Faculty of Public Health, Universitas Airlangga, 
      Surabaya, Indonesia.
FAU - Khaneghah, Amin Mousavi
AU  - Khaneghah AM
AD  - Department of Fruit and Vegetable Product Technology, Prof. Waclaw Dabrowski 
      Institute of Agricultural and Food Biotechnology - State Research Institute, 
      Warsaw, Poland.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20221114
PL  - Germany
TA  - Rev Environ Health
JT  - Reviews on environmental health
JID - 0425754
SB  - IM
OTO - NOTNLM
OT  - Ochratoxin A
OT  - coffee products
OT  - meta-analysis
OT  - risk assessment
EDAT- 2022/11/14 06:00
MHDA- 2022/11/14 06:00
CRDT- 2022/11/13 22:12
PHST- 2022/07/13 00:00 [received]
PHST- 2022/10/27 00:00 [accepted]
PHST- 2022/11/13 22:12 [entrez]
PHST- 2022/11/14 06:00 [pubmed]
PHST- 2022/11/14 06:00 [medline]
AID - reveh-2022-0115 [pii]
AID - 10.1515/reveh-2022-0115 [doi]
PST - aheadofprint
SO  - Rev Environ Health. 2022 Nov 14. doi: 10.1515/reveh-2022-0115.