PMID- 36375951
OWN - NLM
STAT- MEDLINE
DCOM- 20221116
LR  - 20221116
IS  - 1001-0742 (Print)
IS  - 1001-0742 (Linking)
VI  - 125
DP  - 2023 Mar
TI  - Co-occurrence of genes for antibiotic resistance and arsenic biotransformation in 
      paddy soils.
PG  - 701-711
LID - S1001-0742(22)00087-0 [pii]
LID - 10.1016/j.jes.2022.02.027 [doi]
AB  - Paddy soils are potential hotspots of combined contamination with arsenic (As) 
      and antibiotics, which may induce co-selection of antibiotic resistance genes 
      (ARGs) and As biotransformation genes (ABGs), resulting in dissemination of 
      antimicrobial resistance and modification in As biogeochemical cycling. So far, 
      little information is available for these co-selection processes and specific 
      patterns between ABGs and ARGs in paddy soils. Here, the 16S rRNA amplicon 
      sequencing and high-throughput quantitative PCR and network analysis were 
      employed to investigate the dynamic response of ABGs and ARGs to As stress and 
      manure application. The results showed that As stress increased the abundance of 
      ARGs and mobile genetic elements (MGEs), resulting in dissemination risk of 
      antimicrobial resistance. Manure amendment increased the abundance of ABGs, 
      enhanced As mobilization and methylation in paddy soil, posing risk to food 
      safety. The frequency of the co-occurrence between ABGs and ARGs, the host 
      bacteria carrying both ARGs and ABGs were increased by As or manure treatment, 
      and remarkably boosted in soils amended with both As and manure. Multidrug 
      resistance genes were found to have the preference to be co-selected with ABGs, 
      which was one of the dominant co-occurring ARGs in all treatments, and manure 
      amendment increased the frequency of Macrolide-Lincosamide-Streptogramin B 
      resistance (MLSB) to co-occur with ABGs. Bacillus and Clostridium of Firmicutes 
      are the dominant host bacteria carrying both ABGs and ARGs in paddy soils. This 
      study would extend our understanding on the co-selection between genes for 
      antibiotics and metals, also unveil the hidden environmental effects of combined 
      pollution.
CI  - Copyright (c) 2022. Published by Elsevier B.V.
FAU - Cui, Huiling
AU  - Cui H
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China.
FAU - Zhu, Dong
AU  - Zhu D
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China.
FAU - Ding, Longjun
AU  - Ding L
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China.
FAU - Wang, Yifei
AU  - Wang Y
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China.
FAU - Su, Jianqiang
AU  - Su J
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      Key Laboratory of Urban Environment and Health, Institute of Urban Environment, 
      Chinese Academy of Sciences, Xiamen 361021, China.
FAU - Duan, Guilan
AU  - Duan G
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China. Electronic 
      address: duangl@rcees.ac.cn.
FAU - Zhu, Yongguan
AU  - Zhu Y
AD  - State Key Laboratory of Urban and Regional Ecology, Research Center for 
      Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; 
      University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory 
      of Urban Environment and Health, Institute of Urban Environment, Chinese Academy 
      of Sciences, Xiamen 361021, China.
LA  - eng
PT  - Journal Article
DEP - 20220227
PL  - Netherlands
TA  - J Environ Sci (China)
JT  - Journal of environmental sciences (China)
JID - 100967627
RN  - 0 (Soil)
RN  - 0 (Manure)
RN  - N712M78A8G (Arsenic)
RN  - 0 (RNA, Ribosomal, 16S)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - *Soil
MH  - Manure/analysis
MH  - *Arsenic
MH  - RNA, Ribosomal, 16S/genetics
MH  - Genes, Bacterial
MH  - Soil Microbiology
MH  - Drug Resistance, Microbial/genetics
MH  - Anti-Bacterial Agents/pharmacology
MH  - Bacteria/genetics
MH  - Biotransformation
OTO - NOTNLM
OT  - Antibiotic resistance genes
OT  - Arsenic
OT  - Arsenic biotransformation genes
OT  - Co-occurrence
OT  - Host bacteria
EDAT- 2022/11/15 06:00
MHDA- 2022/11/18 06:00
CRDT- 2022/11/14 21:05
PHST- 2021/12/19 00:00 [received]
PHST- 2022/02/15 00:00 [revised]
PHST- 2022/02/16 00:00 [accepted]
PHST- 2022/11/14 21:05 [entrez]
PHST- 2022/11/15 06:00 [pubmed]
PHST- 2022/11/18 06:00 [medline]
AID - S1001-0742(22)00087-0 [pii]
AID - 10.1016/j.jes.2022.02.027 [doi]
PST - ppublish
SO  - J Environ Sci (China). 2023 Mar;125:701-711. doi: 10.1016/j.jes.2022.02.027. Epub 
      2022 Feb 27.