PMID- 36380307
OWN - NLM
STAT- MEDLINE
DCOM- 20221118
LR  - 20221203
IS  - 1471-244X (Electronic)
IS  - 1471-244X (Linking)
VI  - 22
IP  - 1
DP  - 2022 Nov 15
TI  - ADHD in adults with major depressive or bipolar disorder: does it affect clinical 
      features, comorbidity, quality of life, and global functioning?
PG  - 707
LID - 10.1186/s12888-022-04273-8 [doi]
LID - 707
AB  - BACKGROUND: This study compared clinical characteristics, concurrent disorders, 
      level of function, and quality of life in adults with bipolar (BD) or major 
      depressive disorder (MDD) in those with/without adult attention defici1t 
      hyperactivity disorder (AADHD). METHODS: The participants were recruited among 
      adult inpatients and outpatients with MDD or BD in their current partial 
      remission in a psychiatric hospital. They were evaluated using the interview for 
      adults with ADHD (DIVA-5), Conners' Adult ADHD Rating 
      Scales-Self-Report-Screening Version (CAARS-SR-SV), Structured Clinical Interview 
      for DSM-V (SCID-5), Beck Depression Inventory-II and Young Mania Rating Scale, 
      Global Assessment of Functioning (GAF) and World Health Organization Quality of 
      Life Scale-Brief (WHOQoL-BREF). RESULTS: In those with MDD (n = 105) and BD 
      (n = 103), AADHD was detected as 13.3% and 16.5%, respectively. The inattentive 
      presentation was the most prevalent type among patients with AADHD. Compared to 
      the patients without AADHD, the results regarding the prevalence of 
      comorbidities, suicidal attempts, severity of affective episodes, the early 
      emergence of the affective disorders, and level of quality of life and global 
      functioning were poorer in the group with AADHD (p < 0.05). LIMITATIONS: The 
      participants were individuals with major depressive or bipolar type I disorder 
      with a mostly manic episode, chosen among the referrals to a tertiary psychiatric 
      hospital with high comorbidity and more severe psychopathology. This may limit 
      the generalizability of the findings. CONCLUSION: ADHD was common in adults with 
      MDD and BD, along with high psychiatric comorbidity and negative consequences. 
      Clinicians are suggested to screen adults with mood disorders for the symptoms of 
      ADHD for a more precise and comprehensive diagnosis and to provide a more 
      appropriate therapeutic intervention.
CI  - (c) 2022. The Author(s).
FAU - Sadeghian Nadooshan, Mohammad Reza
AU  - Sadeghian Nadooshan MR
AD  - Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Shahrivar, Zahra
AU  - Shahrivar Z
AD  - Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical 
      Sciences, Tehran, Iran. sharivar@sina.tums.ac.ir.
FAU - Mahmoudi Gharaie, Javad
AU  - Mahmoudi Gharaie J
AD  - Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical 
      Sciences, Tehran, Iran.
FAU - Salehi, Leyla
AU  - Salehi L
AD  - Department of Psychiatry, Roozbeh Hospital, Tehran University of Medical 
      Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
DEP - 20221115
PL  - England
TA  - BMC Psychiatry
JT  - BMC psychiatry
JID - 100968559
SB  - IM
MH  - Adult
MH  - Humans
MH  - *Bipolar Disorder/complications/epidemiology/diagnosis
MH  - *Attention Deficit Disorder with 
      Hyperactivity/complications/diagnosis/epidemiology
MH  - Quality of Life
MH  - *Depressive Disorder, Major/diagnosis/epidemiology
MH  - Psychiatric Status Rating Scales
MH  - Comorbidity
PMC - PMC9667673
OTO - NOTNLM
OT  - Adult ADHD
OT  - Bipolar
OT  - Comorbidity
OT  - Depression
OT  - Function
OT  - Quality of life
COIS- The authors declare no conflict of interest.
EDAT- 2022/11/16 06:00
MHDA- 2022/11/19 06:00
PMCR- 2022/11/15
CRDT- 2022/11/15 23:58
PHST- 2021/11/14 00:00 [received]
PHST- 2022/09/23 00:00 [accepted]
PHST- 2022/11/15 23:58 [entrez]
PHST- 2022/11/16 06:00 [pubmed]
PHST- 2022/11/19 06:00 [medline]
PHST- 2022/11/15 00:00 [pmc-release]
AID - 10.1186/s12888-022-04273-8 [pii]
AID - 4273 [pii]
AID - 10.1186/s12888-022-04273-8 [doi]
PST - epublish
SO  - BMC Psychiatry. 2022 Nov 15;22(1):707. doi: 10.1186/s12888-022-04273-8.