PMID- 36381703
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221117
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 10
DP  - 2022 Oct
TI  - Angioedema of Vermilion Border Lip: A Case Report.
PG  - e30142
LID - 10.7759/cureus.30142 [doi]
LID - e30142
AB  - Angioedema is the diffuse edematous swelling of the soft tissues that most 
      commonly involves the submucosal and subcutaneous connective tissues. It can also 
      affect the connective tissues of the respiratory and gastrointestinal tract. The 
      most common pathogenesis is the degranulation of mast cells, leading to histamine 
      release and increased vascular permeability. The immunoglobulin E (IgE)-mediated 
      hypersensitivity reactions are triggered by foods, preservatives such as sodium 
      benzoate used in peanut butter, dust, drugs like angiotensin-converting enzyme 
      inhibitors (ACE) like captopril, enalapril, lisinopril and pollens, and contact 
      allergies started by prolonged contact with dental rubber dams and cosmetics. 
      Hereditary factors such as quantitative reduction of C1 esterase inhibitor 
      (C1-INH) deficiency and dysfunctional C1 esterase inhibitor (C1-INH) are also 
      postulated in its etiopathogenesis. In addition, lymphoproliferative disorders, 
      bacterial or viral infections, lupus erythematosus, and minor trauma from dental 
      procedures may precipitate an angioedema attack.
CI  - Copyright (c) 2022, Rajaram Mohan et al.
FAU - Rajaram Mohan, Karthik
AU  - Rajaram Mohan K
AD  - Oral Medicine and Radiology, Vinayaka Mission's Sankarachariyar Dental College, 
      Vinayaka Mission's Research Foundation - DU, Salem, IND.
FAU - Chinnakutti, Suresh
AU  - Chinnakutti S
AD  - Oral and Maxillofacial Surgery, Vinayaka Mission's Sankarachariyar Dental 
      College, Vinayaka Mission's Research Foundation - DU, Salem, IND.
FAU - Murugesan, Devaki
AU  - Murugesan D
AD  - Oral Medicine and Radiology, Kanyakumari Government Medical College, Kanyakumari, 
      IND.
FAU - Govind Raj, Sarathchandra
AU  - Govind Raj S
AD  - Prosthodontics, Rajas Dental College, Tirunelveli, IND.
FAU - Ganesan, Rajesh Kumar
AU  - Ganesan RK
AD  - Dentistry, Pandian Multispeciality Dental Clinic, Thammampatti, IND.
LA  - eng
PT  - Case Reports
DEP - 20221010
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9645611
OTO - NOTNLM
OT  - angioedema
OT  - angiotensin converting enzyme inhibitors
OT  - c1 esterase inhibitor
OT  - ige-mediated
OT  - peanut
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/11/17 06:00
MHDA- 2022/11/17 06:01
PMCR- 2022/10/10
CRDT- 2022/11/16 02:56
PHST- 2022/10/07 00:00 [accepted]
PHST- 2022/11/16 02:56 [entrez]
PHST- 2022/11/17 06:00 [pubmed]
PHST- 2022/11/17 06:01 [medline]
PHST- 2022/10/10 00:00 [pmc-release]
AID - 10.7759/cureus.30142 [doi]
PST - epublish
SO  - Cureus. 2022 Oct 10;14(10):e30142. doi: 10.7759/cureus.30142. eCollection 2022 
      Oct.