PMID- 36385917
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221118
IS  - 2215-0161 (Print)
IS  - 2215-0161 (Electronic)
IS  - 2215-0161 (Linking)
VI  - 9
DP  - 2022
TI  - Online analysis of chemical composition and size distribution of fresh cigarette 
      smoke emitted from a heated tobacco product.
PG  - 101912
LID - 10.1016/j.mex.2022.101912 [doi]
LID - 101912
AB  - Online analysis of chemical composition of cigarette smoke of a heated tobacco 
      product (HTP) was performed by using a home-made vacuum ultraviolet (VUV) 
      lamp-based photoionization time-of-flight (TOF) mass spectrometer. A capillary 
      inlet and an aerodynamic lens were utilized to sample the gas- and 
      particulate-phase of the HTP smoke, without dilution and pretreatment, which can 
      be switched from each other within minutes. A thermal desorption unit was 
      installed to vaporize the particulate-phase into gas and its vaporization 
      temperature was determined, based on an equilibrium between the evaporation 
      efficiency and the thermal decomposition of organic compounds. Then these species 
      were softly ionized by VUV photons and their ions were measured by a reflectron 
      TOF mass analyzer. Meanwhile, the puff-by-puff resolved size distributions of the 
      HTP smoke were probed with a commercial scanning mobility particle sizers (SMPS). 
      The mean diameters of particles firstly increase with the puff number, mainly 
      located in the range of 200 - 300 nm, and then approached a steady state. This 
      method was validated to measure the physical-chemical characteristics of the HTP 
      cigarette smoke.*A capillary inlet and an aerodynamic lens were utilized to 
      sample the gas- and particulate-phase of the HTP smoke.*Chemical composition of 
      the HTP smoke was measured by using a compact VUV photoionization mass 
      spectrometer.*The particle size distribution of the HTP smoke without dilution 
      was measured online.
CI  - (c) 2022 The Author(s).
FAU - Wen, Zuoying
AU  - Wen Z
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
FAU - Li, Xiangyu
AU  - Li X
AD  - China National Tobacco Quality Supervision & Test Centre, Zhengzhou 450001, 
      Henan, China.
FAU - Gu, Xuejun
AU  - Gu X
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
FAU - Zhang, Weijun
AU  - Zhang W
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
FAU - Pang, Yongqiang
AU  - Pang Y
AD  - China National Tobacco Quality Supervision & Test Centre, Zhengzhou 450001, 
      Henan, China.
FAU - Jiang, Xingyi
AU  - Jiang X
AD  - China National Tobacco Quality Supervision & Test Centre, Zhengzhou 450001, 
      Henan, China.
FAU - Hou, Hongwei
AU  - Hou H
AD  - China National Tobacco Quality Supervision & Test Centre, Zhengzhou 450001, 
      Henan, China.
FAU - Hu, Qingyuan
AU  - Hu Q
AD  - China National Tobacco Quality Supervision & Test Centre, Zhengzhou 450001, 
      Henan, China.
FAU - Wang, Jian
AU  - Wang J
AD  - Key Laboratory of Combustion and Pyrolysis, China Tobacco Anhui Industrial Co. 
      Ltd., Hefei 230088, Anhui, China.
FAU - Zhang, Long
AU  - Zhang L
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
FAU - Liu, Yong
AU  - Liu Y
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
FAU - Tang, Xiaofeng
AU  - Tang X
AD  - Anhui Institute of Optics and Fine Mechanics, HFIPS, Chinese Academy of Sciences, 
      Hefei 230031, Anhui, China.
LA  - eng
PT  - Journal Article
DEP - 20221104
PL  - Netherlands
TA  - MethodsX
JT  - MethodsX
JID - 101639829
PMC - PMC9661439
OTO - NOTNLM
OT  - Cigarette smoke
OT  - Heated tobacco product
OT  - Online chemical analysis
OT  - Particulate matter
OT  - Size distribution
OT  - VUV photoionization mass spectrometry
EDAT- 2022/11/18 06:00
MHDA- 2022/11/18 06:01
PMCR- 2022/11/04
CRDT- 2022/11/17 11:35
PHST- 2021/11/19 00:00 [received]
PHST- 2022/10/30 00:00 [accepted]
PHST- 2022/11/17 11:35 [entrez]
PHST- 2022/11/18 06:00 [pubmed]
PHST- 2022/11/18 06:01 [medline]
PHST- 2022/11/04 00:00 [pmc-release]
AID - S2215-0161(22)00289-8 [pii]
AID - 101912 [pii]
AID - 10.1016/j.mex.2022.101912 [doi]
PST - epublish
SO  - MethodsX. 2022 Nov 4;9:101912. doi: 10.1016/j.mex.2022.101912. eCollection 2022.