PMID- 36389377 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221119 IS - 2296-2360 (Print) IS - 2296-2360 (Electronic) IS - 2296-2360 (Linking) VI - 10 DP - 2022 TI - Lifestyle indices of body composition and obesity risk and prevalence among multi-ethnic adolescents in Malaysia. PG - 899014 LID - 10.3389/fped.2022.899014 [doi] LID - 899014 AB - The prevalence of childhood obesity in Malaysia has doubled in less than a decade. Moreover, being overweight and obese have been associated with immediate and later comorbidities, thus emphasizing the need to prevent obesity from an early age. This cross-sectional study involved 923 multi-ethnic Malaysian adolescents aged between 15 and 17 years old. Body composition was estimated using bioelectrical impedance analysis. Body mass index (BMI) classification was based on the World Health Organization (WHO) growth reference and the International Obesity Task Force (IOTF) cut-off. Meanwhile, the Child Growth Foundation (CGF) body fat reference was used to classify adolescents' adiposity. Lifestyle indices including physical activity, sedentary behavior, supplement intake, smoking and alcohol status were assessed via questionnaires. A high prevalence of overweight/obesity among the adolescents was observed according to the CGF (26%), followed by that of the WHO (24%) and then the IOTF (23%) cut-off, with high concordance values between each pair. After adjustment, a significant association was found between physical activity (PAQ score) and lean mass (p = 0.027). No lifestyle determinant was found to be a significant predictor of fat percentage. A high sedentary level increased the likelihood of obesity (OR 3.0, p < 0.01), while antioxidant-rich supplements were found to protect against obesity (OR 0.4, p < 0.05). The lifestyle predictors identified in this study may be considered when designing interventions that integrate lifestyle modifications targeting adolescents. CI - (c) 2022 Zulfarina, Sharif, Mokhtar, Shuid and Naina-Mohamed. FAU - Zulfarina, Mohamed S AU - Zulfarina MS AD - Pharmacoepidemiology and Drug Safety Unit, Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Malaysia. FAU - Sharif, Razinah AU - Sharif R AD - Nutritional Science Program and Centre for Healthy Ageing and Wellness, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. FAU - Mokhtar, Sabarul Afian AU - Mokhtar SA AD - Pro Vice-Chancellor's Office, Health Campus, Cheras, Malaysia. FAU - Shuid, Ahmad Nazrun AU - Shuid AN AD - Department of Pharmacology, Faculty of Medicine, Universiti Teknologi MARA, Sungai Buloh, Malaysia. FAU - Naina-Mohamed, Isa AU - Naina-Mohamed I AD - Pharmacoepidemiology and Drug Safety Unit, Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, Malaysia. LA - eng PT - Journal Article DEP - 20221101 PL - Switzerland TA - Front Pediatr JT - Frontiers in pediatrics JID - 101615492 PMC - PMC9663460 OTO - NOTNLM OT - LEAN MASS OT - antioxidants OT - body fat OT - obese OT - physical activity OT - sedentary behavior COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/11/18 06:00 MHDA- 2022/11/18 06:01 PMCR- 2022/11/01 CRDT- 2022/11/17 12:36 PHST- 2022/08/17 00:00 [received] PHST- 2022/10/10 00:00 [accepted] PHST- 2022/11/17 12:36 [entrez] PHST- 2022/11/18 06:00 [pubmed] PHST- 2022/11/18 06:01 [medline] PHST- 2022/11/01 00:00 [pmc-release] AID - 10.3389/fped.2022.899014 [doi] PST - epublish SO - Front Pediatr. 2022 Nov 1;10:899014. doi: 10.3389/fped.2022.899014. eCollection 2022.