PMID- 36395635 OWN - NLM STAT- MEDLINE DCOM- 20230124 LR - 20230202 IS - 1873-6947 (Electronic) IS - 1744-3881 (Linking) VI - 50 DP - 2023 Feb TI - Tele-yoga in the management of ankylosing spondylitis amidst COVID pandemic: A prospective randomized controlled trial. PG - 101672 LID - S1744-3881(22)00140-2 [pii] LID - 10.1016/j.ctcp.2022.101672 [doi] AB - PURPOSE: Ankylosing spondylitis (AS) signficantly affect day to day activities contributing to signficant disability. Patients with AS often report to have psychological problems and poor quality of life (QoL). This study investigates the effect of a three-month tele-yogic intervention on disease activity, functional index, inflammatory markers, quality of life and mental health measures in patients with AS. METHODS: One hundred and twenty AS patients were assigned to either the yoga intervention group (YG) or the control group (CG). The YG (n = 57) received a 60-min structured yoga module online for 3 months in addition to standard medical care. The CG participants (n = 52) received only standard care during the same period. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis-Quality of Life (ASQOL) and psychological and inflammatory biomarkers were assessed at baseline and after three months. RESULTS: YG showed significant improvement in BASDAI (p = 0.001), anxiety (p = 0.0004), and depression (p = 0.001) at three months compared to baseline. The CG showed no significant change in similar outcome measures. At three months, the intervention resulted in a significant improvement in BASDI (-0.79; 95% CI (-1.3, to -0.29); p = 0.0021), BASFI (-0.86, 95% CI (-1.59, to -0.14); p = 0.0193), anxiety (-0.42, 95% CI (-0.84 to -0.01), p = 0.0468), and AS-QoL (-3.37; 95% CI (-5.21 to 1.53); p = 0.0004) compared to the CG. CONCLUSIONS: The present study suggests that yoga helps improve pain, functional index, and mental health in patients with AS. Tele-yoga intervention is feasible and effective in treating AS. CI - Copyright (c) 2022. Published by Elsevier Ltd. FAU - Singh, Jyoti AU - Singh J AD - Division of Yoga & Life Swami Vivekananda Yoga Anusandhan Samsthan, #19 Eknath Bhavan, Gavipuram circle, K G Nagar, Bengaluru, 560019, India. Electronic address: raahisingh16042014@gmail.com. FAU - Metri, Kashinath AU - Metri K AD - Department of Yoga, Central University of Rajasthan, India. Electronic address: kgmhetre@gmail.com. FAU - Tekur, Padmini AU - Tekur P AD - Division of Yoga & Life Swami Vivekananda Yoga Anusandhan Samsthan, #19 Eknath Bhavan, Gavipuram circle, K G Nagar, Bengaluru, 560019, India. Electronic address: padmini.tekur@svyasa.edu.in. FAU - Mohanty, Sriloy AU - Mohanty S AD - Centers for Integrative Medicine and Research, All India Institute of Medical Sciences, New Delhi, India. Electronic address: sriloy21@aiims.ac.in. FAU - Singh, Amit AU - Singh A AD - Division of Yoga & Life Swami Vivekananda Yoga Anusandhan Samsthan, #19 Eknath Bhavan, Gavipuram circle, K G Nagar, Bengaluru, 560019, India. Electronic address: dramit@svyasa.edu.in. FAU - Raghuram, Nagaratna AU - Raghuram N AD - Division of Yoga & Life Swami Vivekananda Yoga Anusandhan Samsthan, #19 Eknath Bhavan, Gavipuram circle, K G Nagar, Bengaluru, 560019, India. Electronic address: rnagarathana@svyasa.edu.in. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20221022 PL - England TA - Complement Ther Clin Pract JT - Complementary therapies in clinical practice JID - 101225531 MH - Humans MH - *Spondylitis, Ankylosing/therapy MH - Quality of Life/psychology MH - *Yoga MH - Pandemics MH - Prospective Studies MH - Surveys and Questionnaires MH - *COVID-19 MH - Severity of Illness Index OTO - NOTNLM OT - And meditation OT - Autoimmune disease OT - Mind-body medicine OT - Pain OT - Rheumatology OT - Yoga COIS- Declaration of competing interest The authors declare no conflict of interest. EDAT- 2022/11/18 06:00 MHDA- 2023/01/25 06:00 CRDT- 2022/11/17 18:23 PHST- 2022/06/17 00:00 [received] PHST- 2022/09/15 00:00 [revised] PHST- 2022/10/13 00:00 [accepted] PHST- 2022/11/18 06:00 [pubmed] PHST- 2023/01/25 06:00 [medline] PHST- 2022/11/17 18:23 [entrez] AID - S1744-3881(22)00140-2 [pii] AID - 10.1016/j.ctcp.2022.101672 [doi] PST - ppublish SO - Complement Ther Clin Pract. 2023 Feb;50:101672. doi: 10.1016/j.ctcp.2022.101672. Epub 2022 Oct 22.