PMID- 36395907 OWN - NLM STAT- MEDLINE DCOM- 20221205 LR - 20240102 IS - 1873-6424 (Electronic) IS - 0269-7491 (Print) IS - 0269-7491 (Linking) VI - 316 IP - Pt 2 DP - 2023 Jan 1 TI - An exploratory spatial contaminant assessment for polar bear (Ursus maritimus) liver, fat, and muscle from northern Canada. PG - 120663 LID - S0269-7491(22)01877-2 [pii] LID - 10.1016/j.envpol.2022.120663 [doi] AB - Since the industrial era, chemicals have been ubiquitous in worldwide ecosystems. Despite the discontinued release of highly toxic persistent organic pollutants (POPs) in the environment, the levels of some POPs are still being measured in the Canadian Arctic. These contaminants are of great concern due to their persistence, toxicity, and levels of bioaccumulation in food chains. Animals occupying top trophic positions in the Canadian Arctic, particularly polar bears, are exposed to these contaminants mainly through their diet. Our study investigated the levels of 30 metals (including total and methyl mercury) alkaline and alkaline earth metals, 15 polycyclic aromatic compounds and their alkyl congeners (PACs), 6 chlordanes (CHLs), and 20 polychlorinated biphenyls (PCBs), in 49 polar bears from the Canadian Arctic. Contaminant burden was measured in liver, muscle, and fat in bears of different sex, age, and locations. A principal component analysis did not distinguish differences between age and sex profiles for most contaminants. However, the concentrations measured and their distribution in the tissues confirm findings observed in past studies. This study highlights the importance of continual monitoring of polar bear health (e.g., newly detected PACs were measured within this study) and evaluating those impacts for the next generations of polar bears. CI - Copyright (c) 2022 Elsevier Ltd. All rights reserved. FAU - Boutet, V AU - Boutet V AD - Institut national de la recherche scientifique (INRS), Quebec, Canada. FAU - Dominique, M AU - Dominique M AD - Institut national de la recherche scientifique (INRS), Quebec, Canada. FAU - Eccles, K M AU - Eccles KM AD - National Institute of Environmental Health Science, Division of the National Toxicology Program, Durham, USA. FAU - Branigan, M AU - Branigan M AD - Government of the Northwest Territories, Canada. FAU - Dyck, M AU - Dyck M AD - Government of Nunavut, Department of Environment, Igloolik, NU, Canada. FAU - van Coeverden de Groot, P AU - van Coeverden de Groot P AD - Biology Department, Queen's University, Kingston, ON, Canada. FAU - Lougheed, S C AU - Lougheed SC AD - Biology Department, Queen's University, Kingston, ON, Canada. FAU - Rutter, A AU - Rutter A AD - School of Environmental Studies, Queen's University, Kingston, ON, Canada. FAU - Langlois, V S AU - Langlois VS AD - Institut national de la recherche scientifique (INRS), Quebec, Canada. Electronic address: valerie.langlois@inrs.ca. LA - eng GR - Z99 ES999999/ImNIH/Intramural NIH HHS/United States PT - Journal Article DEP - 20221114 PL - England TA - Environ Pollut JT - Environmental pollution (Barking, Essex : 1987) JID - 8804476 RN - 0 (Polycyclic Compounds) SB - IM MH - Animals MH - *Ursidae MH - Ecosystem MH - Canada MH - Muscles MH - Liver MH - *Polycyclic Compounds PMC - PMC10163957 MID - NIHMS1891877 OTO - NOTNLM OT - Arctic OT - Metals OT - Persistent organic compounds OT - Pesticides OT - Polychlorinated biphenyls OT - Polycyclic aromatic compounds COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/11/18 06:00 MHDA- 2022/12/06 06:00 PMCR- 2024/01/01 CRDT- 2022/11/17 19:24 PHST- 2022/04/26 00:00 [received] PHST- 2022/11/11 00:00 [revised] PHST- 2022/11/12 00:00 [accepted] PHST- 2022/11/18 06:00 [pubmed] PHST- 2022/12/06 06:00 [medline] PHST- 2022/11/17 19:24 [entrez] PHST- 2024/01/01 00:00 [pmc-release] AID - S0269-7491(22)01877-2 [pii] AID - 10.1016/j.envpol.2022.120663 [doi] PST - ppublish SO - Environ Pollut. 2023 Jan 1;316(Pt 2):120663. doi: 10.1016/j.envpol.2022.120663. Epub 2022 Nov 14.