PMID- 36397222 OWN - NLM STAT- MEDLINE DCOM- 20221121 LR - 20221121 IS - 0255-2930 (Print) IS - 0255-2930 (Linking) VI - 42 IP - 11 DP - 2022 Nov 12 TI - [Minimal clinically important difference of the frequency of bowel movement for patients with chronic severe functional constipation treated with acupuncture]. PG - 1247-50 LID - 10.13703/j.0255-2930.20210902-k0007 [doi] AB - OBJECTIVE: To estimate the minimal clinically important difference (MCID) of the frequency of bowel movement for the patients with chronic severe functional constipation treated with acupuncture so as to provide the evidence for the clinical decision. METHODS: In this study, 813 patients with chronic severe functional constipation treated with acupuncture in two previous randomized controlled trials were included. Through the anchor-based method (anchored by the item 28 "satisfaction with previous treatment" of the patient assessment of constipation-quality of life [PAC-QOL]) and the distribution-based method, the MCID of the weekly frequency of complete spontaneous bowel movement (CSBM) and spontaneous bowel movement (SBM) was analyzed statistically in the patients. RESULTS: The MCID of the mean weekly frequency of CSBM and SBM was 1.3 times and 1.6 times in patients with chronic severe functional constipation treated with acupuncture, respectively. CONCLUSION: The mean increase of the weekly CSMB is >/= 1.3 times and that of SBM is >/= 1.6 times after treatment when compared with the baseline respectively, suggesting the clinical significance. FAU - Ai, Yan-Ke AU - Ai YK AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. FAU - Liu, Zhi-Shun AU - Liu ZS AD - Department of Acupuncture and Moxibustion, Guang' anmen Hospital, China Academy of Chinese Medical Sciences. FAU - Liu, Bao-Yan AU - Liu BY AD - TCM Data Center, China Academy of Chinese Medical Sciences. FAU - Zhang, Yan-Hong AU - Zhang YH AD - Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences. FAU - Li, Yang AU - Li Y AD - Department of Acupuncture and Moxibustion, Beijing Fengtai You'anmen Hospital. FAU - Sun, Hai-Shu AU - Sun HS AD - Institute of Chinese Medicine Information, China Academy of Chinese Medical Sciences. FAU - Cao, Xue AU - Cao X AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. FAU - Liu, Jia AU - Liu J AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. FAU - Yang, Zhuo-Xin AU - Yang ZX AD - Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital. FAU - Yu, Hai-Bo AU - Yu HB AD - Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital. FAU - Huang, Xing-Xian AU - Huang XX AD - Department of Acupuncture and Moxibustion, Shenzhen TCM Hospital. FAU - He, Li-Yun AU - He LY AD - Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. LA - chi PT - English Abstract PT - Journal Article PL - China TA - Zhongguo Zhen Jiu JT - Zhongguo zhen jiu = Chinese acupuncture & moxibustion JID - 8600658 SB - IM MH - Humans MH - *Quality of Life MH - Minimal Clinically Important Difference MH - Treatment Outcome MH - Constipation/therapy MH - *Acupuncture Therapy OTO - NOTNLM OT - acupuncture OT - chronic severe functional constipation OT - frequency of complete spontaneous bowel movement OT - frequency of spontaneous bowel movements OT - minimal clinically important difference (MCID) EDAT- 2022/11/19 06:00 MHDA- 2022/11/22 06:00 CRDT- 2022/11/18 00:20 PHST- 2022/11/18 00:20 [entrez] PHST- 2022/11/19 06:00 [pubmed] PHST- 2022/11/22 06:00 [medline] AID - 10.13703/j.0255-2930.20210902-k0007 [doi] PST - ppublish SO - Zhongguo Zhen Jiu. 2022 Nov 12;42(11):1247-50. doi: 10.13703/j.0255-2930.20210902-k0007.