PMID- 36400551 OWN - NLM STAT- MEDLINE DCOM- 20221122 LR - 20221130 IS - 1557-9875 (Electronic) IS - 0733-8619 (Linking) VI - 41 IP - 1 DP - 2023 Feb TI - Management of Psychiatric Symptoms in Dementia. PG - 123-139 LID - S0733-8619(22)00041-X [pii] LID - 10.1016/j.ncl.2022.05.001 [doi] AB - Behavioral and Psychological Symptoms of Dementia (BPSD) are frequent, may start early in the disease and increase in frequency and severity over time. BPSD may be associated with medical, social, emotional, and environmental factors and potential triggers should be eliminated. Each BPSD has a unique anatomic and neurochemical profile that may help in making a diagnosis and choosing a therapy. Structured management plans help create an effective framework. Treatment options are understudied and the evidence is inconclusive for many of the pharmacological interventions. Effective nonpharmacological options should be utilized where available. Treatments should be monitored for their efficacy and safety. CI - Copyright (c) 2022 Elsevier Inc. All rights reserved. FAU - Ayhan, Yavuz AU - Ayhan Y AD - Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, Suite 190, San Francisco, CA 94158, USA; Global Brain Health Institute, University of California, San Francisco (UCSF), 1651 4th St, 3rd Floor, San Francisco, CA 94143, USA; Trinity College Dublin, Dublin, Ireland; Department of Psychiatry, Hacettepe University Faculty of Medicine, 06230, Sihhiye/ Altindag/ Ankara, Turkey. Electronic address: yavuz.ayhan@gbhi.org. FAU - Yoseph, Selam A AU - Yoseph SA AD - Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, Suite 190, San Francisco, CA 94158, USA; Global Brain Health Institute, University of California, San Francisco (UCSF), 1651 4th St, 3rd Floor, San Francisco, CA 94143, USA; Trinity College Dublin, Dublin, Ireland; Department of Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia. FAU - Miller, Bruce L AU - Miller BL AD - Department of Neurology, Memory and Aging Center, Weill Institute for Neurosciences, University of California, 675 Nelson Rising Lane, Suite 190, San Francisco, CA 94158, USA; Global Brain Health Institute, University of California, San Francisco (UCSF), 1651 4th St, 3rd Floor, San Francisco, CA 94143, USA; Trinity College Dublin, Dublin, Ireland. LA - eng PT - Journal Article PT - Review DEP - 20221018 PL - United States TA - Neurol Clin JT - Neurologic clinics JID - 8219232 SB - IM MH - Humans MH - *Dementia/complications/therapy/diagnosis OTO - NOTNLM OT - Agitation OT - Apathy OT - Behavioral and psychological symptoms of dementia (BPSD) OT - Dementia OT - Depression OT - Neuropsychiatric OT - Psychosis EDAT- 2022/11/19 06:00 MHDA- 2022/11/23 06:00 CRDT- 2022/11/18 21:07 PHST- 2022/11/18 21:07 [entrez] PHST- 2022/11/19 06:00 [pubmed] PHST- 2022/11/23 06:00 [medline] AID - S0733-8619(22)00041-X [pii] AID - 10.1016/j.ncl.2022.05.001 [doi] PST - ppublish SO - Neurol Clin. 2023 Feb;41(1):123-139. doi: 10.1016/j.ncl.2022.05.001. Epub 2022 Oct 18.