PMID- 36401131
OWN - NLM
STAT- MEDLINE
DCOM- 20230208
LR  - 20230516
IS  - 2366-0058 (Electronic)
VI  - 48
IP  - 2
DP  - 2023 Feb
TI  - Whole-tumor ADC histogram analysis for differentiating endometriosis-related 
      tumors: seromucinous borderline tumor, clear cell carcinoma and endometrioid 
      carcinoma.
PG  - 724-732
LID - 10.1007/s00261-022-03742-8 [doi]
AB  - PURPOSE: To investigate the feasibility of whole-tumor apparent diffusion 
      coefficient (ADC) histogram analysis for improving the differentiation of 
      endometriosis-related tumors: seromucinous borderline tumor (SMBT), clear cell 
      carcinoma (CCC) and endometrioid carcinoma (EC). METHODS: Clinical features, 
      solid component ADC (ADC(SC)) and whole-tumor ADC histogram-derived parameters 
      (volume, the ADC(mean), 10th, 50th and 90th percentile ADCs, inhomogeneity, 
      skewness, kurtosis and entropy) were compared among 22 SMBTs, 42 CCCs and 21 ECs. 
      Statistical analyses were performed using chi-square test, one-way ANOVA or 
      Kruskal-Wallis test, and receiver operating characteristic curves. RESULTS: A 
      significantly higher ADC(SC) and smaller volume were associated with SMBT than 
      with CCC/EC. The ADC(mean) was significantly higher in CCC than in EC. The 10th 
      percentile ADC was significantly lower in EC than in SMBT/CCC. The 50th and 90th 
      percentile ADCs were significantly higher in CCC than in SMBT/EC. For 
      differentiating SMBT from CCC, AUCs of the ADC(SC), volume, and 50th and 90th 
      percentile ADCs were 0.97, 0.86, 0.72 and 0.81, respectively. For differentiating 
      SMBT from EC, AUCs of the ADC(SC), volume and 10th percentile ADC were 0.97, 0.71 
      and 0.72, respectively. For differentiating CCC from EC, AUCs of the ADC(mean) 
      and 10th, 50th and 90th percentile ADCs were 0.79, 0.72, 0.81 and 0.85, 
      respectively. CONCLUSION: Whole-tumor ADC histogram analysis was valuable for 
      differentiating endometriosis-related tumors, and the 90th percentile ADC was 
      optimal in differentiating CCC from EC.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Lu, Jing
AU  - Lu J
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China.
FAU - Zhao, Shuhui
AU  - Zhao S
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China.
AD  - Department of Radiology, Xinhua Hospital, Medical College of Shanghai Jiao Tong 
      University, Shanghai, 200092, People's Republic of China.
FAU - Ma, Fenghua
AU  - Ma F
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China.
AD  - Department of Radiology, Obstetrics and Gynecology Hospital, Fudan University, 
      419 Fangxie Road, Shanghai, 200011, People's Republic of China.
FAU - Li, Haiming
AU  - Li H
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China.
AD  - Department of Radiology, Shanghai Cancer Center, Fudan University, 270 Dongan 
      Road, Shanghai, 200032, People's Republic of China.
FAU - Li, Yong'ai
AU  - Li Y
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China. pingyaoaiai@163.com.
FAU - Qiang, Jinwei
AU  - Qiang J
AUID- ORCID: 0000-0002-6327-1401
AD  - Department of Radiology, Jinshan Hospital, Fudan University, 1508 Longhang Road, 
      Shanghai, 201508, People's Republic of China. dr.jinweiqiang@163.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20221119
PL  - United States
TA  - Abdom Radiol (NY)
JT  - Abdominal radiology (New York)
JID - 101674571
SB  - IM
MH  - Female
MH  - Humans
MH  - *Carcinoma, Endometrioid/diagnostic imaging
MH  - *Endometriosis/diagnostic imaging
MH  - Diffusion Magnetic Resonance Imaging
MH  - ROC Curve
MH  - *Adenocarcinoma, Clear Cell/diagnostic imaging
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Apparent diffusion coefficient
OT  - Clear cell carcinoma
OT  - Endometrioid carcinoma
OT  - Histogram analysis
OT  - Magnetic resonance imaging
OT  - Seromucinous borderline tumor
EDAT- 2022/11/19 06:00
MHDA- 2023/02/09 06:00
CRDT- 2022/11/18 23:59
PHST- 2022/09/26 00:00 [received]
PHST- 2022/11/04 00:00 [accepted]
PHST- 2022/11/03 00:00 [revised]
PHST- 2022/11/19 06:00 [pubmed]
PHST- 2023/02/09 06:00 [medline]
PHST- 2022/11/18 23:59 [entrez]
AID - 10.1007/s00261-022-03742-8 [pii]
AID - 10.1007/s00261-022-03742-8 [doi]
PST - ppublish
SO  - Abdom Radiol (NY). 2023 Feb;48(2):724-732. doi: 10.1007/s00261-022-03742-8. Epub 
      2022 Nov 19.