PMID- 36403275
OWN - NLM
STAT- MEDLINE
DCOM- 20230105
LR  - 20230111
IS  - 1540-8191 (Electronic)
IS  - 0886-0440 (Linking)
VI  - 37
IP  - 12
DP  - 2022 Dec
TI  - Clinical performance of a novel bioprosthetic surgical aortic valve in a German 
      high-volume center.
PG  - 4833-4840
LID - 10.1111/jocs.17198 [doi]
AB  - BACKGROUND AND AIM: Bioprosthetic surgical aortic valve replacement (SAVR) is 
      increasingly adopted in younger patients. We aimed to analyze mid-term follow-up 
      data after SAVR to assess the performance of the prosthesis. METHODS: Data were 
      collected from a single-center series of 154 patients, who underwent SAVR with a 
      bioprosthetic heart valve with the RESILIA tissue at our Heart Centre in 
      Siegburg. All procedural and midterm patient outcomes were documented. RESULTS: 
      Patients had a mean age of 56.8 +/- 9.9 years, 35.7% were female, and the mean 
      logistic European system for cardiac operative risk evaluation (EuroSCORE) was 
      3.4 +/- 3.6%. Diabetes (12.3%), atrial fibrillation (10.4%), and chronic 
      obstructive pulmonary disease (COPD) (5.8%) were common comorbidities. The mean 
      surgery duration was 163.8 +/- 73.4 min, with the 23 mm (34.4%) and 25 mm (33.8%) 
      heart valves being most frequently implanted. At 3-year follow-up, mean pressure 
      gradient was 13.9 +/- 5.9 mmHg, peak gradient was 23.6 +/- 7.7 mmHg, and effective 
      orifice area (EOA) was 1.9 +/- 0.4 cm(2). No patient died during the operation, 3 
      (2.1%) patients within 30 days, and 4 (2.7%) thereafter with an overall mortality 
      of n = 7. Of the surviving patients, 97.8% were in New York Heart Association 
      (NYHA) class I/II and none had structural valve deterioration (SVD). CONCLUSION: 
      Results of our single-center study indicate favorable procedural outcomes. The 
      safety outcomes confirm preliminary earlier results of this novel bioprosthesis 
      but include more patients and a longer midterm follow-up.
CI  - (c) 2022 Wiley Periodicals LLC.
FAU - El-Sayed Ahmad, Ali
AU  - El-Sayed Ahmad A
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
FAU - Giammarino, Sabrina
AU  - Giammarino S
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
FAU - Salamate, Saad
AU  - Salamate S
AUID- ORCID: 0000-0002-0906-0451
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
AD  - Department of Cardiac Surgery, University Hospital Bonn, Bonn, Germany.
FAU - Fehske, Wolfgang
AU  - Fehske W
AUID- ORCID: 0000-0001-8087-5736
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
FAU - Sirat, Sami
AU  - Sirat S
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
FAU - Amer, Mohamed
AU  - Amer M
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
FAU - Bramlage, Peter
AU  - Bramlage P
AUID- ORCID: 0000-0003-4970-2110
AD  - Institute for Pharmacology and Preventive Medicine, Cloppenburg, Germany.
FAU - Bakhtiary, Farhad
AU  - Bakhtiary F
AUID- ORCID: 0000-0002-3042-7182
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
AD  - Department of Cardiac Surgery, University Hospital Bonn, Bonn, Germany.
FAU - Doss, Mirko
AU  - Doss M
AD  - Division of Cardiac Surgery, Heart Centre Siegburg-Wuppertal, University 
      Witten-Herdecke, Witten, Germany.
LA  - eng
GR  - Edwards Lifesciences/
PT  - Journal Article
DEP - 20221120
PL  - United States
TA  - J Card Surg
JT  - Journal of cardiac surgery
JID - 8908809
SB  - IM
MH  - Humans
MH  - Female
MH  - Middle Aged
MH  - Aged
MH  - Male
MH  - Aortic Valve/surgery
MH  - *Heart Valve Prosthesis Implantation/methods
MH  - *Aortic Valve Stenosis/surgery
MH  - Treatment Outcome
MH  - *Heart Valve Prosthesis
MH  - *Bioprosthesis
MH  - Prosthesis Design
OTO - NOTNLM
OT  - INSPIRIS RESILIA
OT  - bioprosthesis
OT  - follow-up
OT  - surgical aortic valve replacement
OT  - young patients
EDAT- 2022/11/21 06:00
MHDA- 2023/01/06 06:00
CRDT- 2022/11/20 16:54
PHST- 2022/09/23 00:00 [revised]
PHST- 2022/04/08 00:00 [received]
PHST- 2022/10/26 00:00 [accepted]
PHST- 2022/11/21 06:00 [pubmed]
PHST- 2023/01/06 06:00 [medline]
PHST- 2022/11/20 16:54 [entrez]
AID - 10.1111/jocs.17198 [doi]
PST - ppublish
SO  - J Card Surg. 2022 Dec;37(12):4833-4840. doi: 10.1111/jocs.17198. Epub 2022 Nov 
      20.