PMID- 36404816 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230701 IS - 2251-6581 (Print) IS - 2251-6581 (Electronic) IS - 2251-6581 (Linking) VI - 21 IP - 2 DP - 2022 Dec TI - Medical management of pancreatic neuroendocrine tumors in patients with MEN 1: case report. PG - 2009-2011 LID - 10.1007/s40200-022-01067-3 [doi] AB - OBJECTIVES: Multiple endocrine neoplasia type 1 (MEN-1) is a rare inherited autosomal dominant disease which manifests itself with at least one clinical scenario before 45 years of age. The value of somatostatin analogue therapy is unknown in the treatment of non-functioning pancreatic tumours and a few studies have been published in this field. CASE PRESENTATION: We report a young patient with MEN-1 with multiple gastric and pancreatic neuroendocrine tumors that was treated with the monthly injection of Sandostatin LAR before and After Distal Pancreatectomy and partial gastrectomy. CONCLUSIONS: Now she is well after four years of treatment with Sandostatin LAR. CI - (c) The Author(s), under exclusive licence to Tehran University of Medical Sciences 2022. FAU - Mohajeri-Tehrani, Mohammad Reza AU - Mohajeri-Tehrani MR AD - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. GRID: grid.411705.6. ISNI: 0000 0001 0166 0922 FAU - Ebrahimpur, Mahbube AU - Ebrahimpur M AUID- ORCID: 0000-0002-0103-4427 AD - Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. GRID: grid.411705.6. ISNI: 0000 0001 0166 0922 FAU - Nasseri-Moghaddam, Siavosh AU - Nasseri-Moghaddam S AD - Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. GRID: grid.411705.6. ISNI: 0000 0001 0166 0922 FAU - Tavangar, Seyed-Mohammad AU - Tavangar SM AD - Department of Pathology, Tehran Medical University of Medical Sciences, Tehran, Iran. GRID: grid.411705.6. ISNI: 0000 0001 0166 0922 FAU - Sani, Mahnaz Pejman AU - Sani MP AD - Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. GRID: grid.411705.6. ISNI: 0000 0001 0166 0922 FAU - Zandi, Abdollah AU - Zandi A AD - Fellowship of bariatric surgery, Atiyeh Hospital, Tehran, Iran. FAU - Shadmehr, Mohammad Behgam AU - Shadmehr MB AD - Tracheal Diseases Research Center (TDRC), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. GRID: grid.411600.2 LA - eng PT - Case Reports DEP - 20220629 PL - Switzerland TA - J Diabetes Metab Disord JT - Journal of diabetes and metabolic disorders JID - 101590741 PMC - PMC9672213 OTO - NOTNLM OT - Case management OT - Multiple endocrine neoplasia OT - Neuroendocrine tumors OT - Octreotide COIS- Conflict of interestAll authors declare no financial and non-financial competing interests. EDAT- 2022/11/22 06:00 MHDA- 2022/11/22 06:01 PMCR- 2023/06/29 CRDT- 2022/11/21 03:45 PHST- 2021/11/17 00:00 [received] PHST- 2022/06/01 00:00 [accepted] PHST- 2022/11/21 03:45 [entrez] PHST- 2022/11/22 06:00 [pubmed] PHST- 2022/11/22 06:01 [medline] PHST- 2023/06/29 00:00 [pmc-release] AID - 1067 [pii] AID - 10.1007/s40200-022-01067-3 [doi] PST - epublish SO - J Diabetes Metab Disord. 2022 Jun 29;21(2):2009-2011. doi: 10.1007/s40200-022-01067-3. eCollection 2022 Dec.