PMID- 36405229
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230413
IS  - 1923-2829 (Print)
IS  - 1923-2837 (Electronic)
IS  - 1923-2829 (Linking)
VI  - 13
IP  - 5
DP  - 2022 Oct
TI  - Analysis of STEMI and NSTEMI in a Community Cohort of Marijuana Users.
PG  - 297-302
LID - 10.14740/cr1340 [doi]
AB  - BACKGROUND: Marijuana is the most commonly used illicit drug in the United 
      States. Current research has yet to come to a consensus on its association with 
      acute coronary syndrome (ACS). Herein, we aimed to analyze how marijuana use 
      relates to acute ST elevation myocardial infarction (STEMI) and non-STEMI 
      (NSTEMI). METHODS: Using a retrospective study design, we gathered data from 
      August 2014 to September 2020 on all percutaneous coronary interventions (PCIs) 
      done at Brookdale University Hospital Medical Center (BUHMC) in patients with 
      NSTEMI and STEMI. To compare marijuana users (MUs) with non-users, t-tests and 
      Chi-square tests were used. A total of 195 patients were included, with mean age 
      at presentation of 47 years old; 59 were females (30.3%) and 136 were males 
      (69.7%). We identified 37 patients who were MUs. MUs were younger than non-users 
      (P < 0.01), had higher rates of alcohol (P = 0.025), opiate (P = 0.004) and 
      cigarette (P </= 0.001) use. On admission, MUs had lower creatinine (P = 0.031), 
      blood urea nitrogen (BUN) (P = 0.031), pro-B-type natriuretic peptide (PBNP) (P = 
      0.052), BMI (P = 0.014) and lower right coronary artery (RCA) disease (P = 
      0.026). RESULTS: After logistic regression analyses, results showed that the 
      severity of coronary artery disease (CAD) and admission diagnosis of STEMI or 
      NSTEMI were not found to be significantly related to marijuana use. Age, alcohol, 
      cigarette, creatinine, BUN, PBNP, BMI and RCA disease were significantly related 
      to marijuana use. There was a negative correlation between marijuana use and RCA 
      disease (MUs = 29.7% vs. non-users = 50%, P = 0.026). There was no significant 
      association with STEMI, NSTEMI or the severity of CAD. CONCLUSION: As daily 
      cannabis use is on the rise, more researches are needed to further determine the 
      effects of marijuana use on CAD.
CI  - Copyright 2022, Jean-Louis et al.
FAU - Jean-Louis, Farla
AU  - Jean-Louis F
AD  - Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
FAU - Adedayo, Ajibola Monsur
AU  - Adedayo AM
AD  - SUNY Downstate Medical Center, Department of Medicine at the Division of 
      Cardiology, Brooklyn, NY, USA.
FAU - Ajibawo Oluwadamilola, Temitope
AU  - Ajibawo Oluwadamilola T
AD  - Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
FAU - Primavera, Louis
AU  - Primavera L
AD  - Associate Provost- Provost Office, The School of Health Sciences of Touro 
      College, Brooklyn, NY, USA.
FAU - Khan, Abdullah
AU  - Khan A
AD  - Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
FAU - Castillo, Ricardo
AU  - Castillo R
AD  - Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
FAU - Chadow, Hal
AU  - Chadow H
AD  - Brookdale University Hospital Medical Center, Brooklyn, NY, USA.
LA  - eng
PT  - Journal Article
DEP - 20221025
PL  - Canada
TA  - Cardiol Res
JT  - Cardiology research
JID - 101557543
PMC - PMC9635778
OTO - NOTNLM
OT  - ACS
OT  - Marijuana
OT  - NSTEMI
OT  - STEMI
COIS- None to declare.
EDAT- 2022/11/22 06:00
MHDA- 2022/11/22 06:01
PMCR- 2022/10/25
CRDT- 2022/11/21 03:52
PHST- 2021/11/30 00:00 [received]
PHST- 2022/03/16 00:00 [accepted]
PHST- 2022/11/21 03:52 [entrez]
PHST- 2022/11/22 06:00 [pubmed]
PHST- 2022/11/22 06:01 [medline]
PHST- 2022/10/25 00:00 [pmc-release]
AID - 10.14740/cr1340 [doi]
PST - ppublish
SO  - Cardiol Res. 2022 Oct;13(5):297-302. doi: 10.14740/cr1340. Epub 2022 Oct 25.