PMID- 36415856
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221124
IS  - 1831-4732 (Electronic)
IS  - 1831-4732 (Linking)
VI  - 20
IP  - 11
DP  - 2022 Nov
TI  - Targeted review of maximum residues levels (MRLs) for haloxyfop-P.
PG  - e07658
LID - 10.2903/j.efsa.2022.7658 [doi]
LID - e07658
AB  - In compliance with Article 43 of Regulation (EC) No 396/2005, the European Food 
      Safety Authority (EFSA) received a mandate from the European Commission to 
      perform a targeted review of the existing maximum residues levels (MRLs) for the 
      active substance haloxyfop-P to check whether the existing EU MRL in onions, 
      sunflower seeds and soya beans (covering codex maximum residue limits (CXLs) or 
      import tolerances) and the proposed import tolerance MRLs in linseeds, 
      rapeseeds/canola seeds are safe for consumers and can eventually be maintained in 
      the MRL Regulation after the expiry of the approval of the active substance. EFSA 
      screened these MRLs considering the toxicological reference values established 
      during the EU peer review process for the renewal of the approval of haloxyfop-P 
      and identified chronic consumer intake concerns for two diets when for the 
      remaining plant and animal commodities, the input values were at the LOQ. 
      Fall-back MRLs could not be proposed, but the additional information provided by 
      EURLs allowed to resolve the chronic intake concerns using lower validated LOQs 
      for a range of plant commodities and milk. EFSA concludes that the existing EU 
      MRLs in soya beans and onions, the CXL in sunflower seeds and the proposed import 
      tolerances in linseed and rapeseed/canola seeds are not expected to pose a risk 
      to consumers. However, to guarantee consumer's safety regarding the chronic 
      exposure to haloxyfop-P residues, the enforcement LOQs in several plant 
      commodities and milks would have to be lowered to the levels reported by the 
      EURLs.
CI  - (c) 2022 Wiley-VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety 
      Authority.
CN  - European Food Safety Authority (EFSA)
FAU - Bellisai, Giulia
AU  - Bellisai G
FAU - Bernasconi, Giovanni
AU  - Bernasconi G
FAU - Brancato, Alba
AU  - Brancato A
FAU - Cabrera, Luis Carrasco
AU  - Cabrera LC
FAU - Castellan, Irene
AU  - Castellan I
FAU - Del Aguila, Monica
AU  - Del Aguila M
FAU - Ferreira, Lucien
AU  - Ferreira L
FAU - Giner, German
AU  - Giner G
FAU - Greco, Luna
AU  - Greco L
FAU - Jarrah, Samira
AU  - Jarrah S
FAU - Leuschner, Renata
AU  - Leuschner R
FAU - Magrans, Jose Oriol
AU  - Magrans JO
FAU - Miron, Ileana
AU  - Miron I
FAU - Nave, Stefanie
AU  - Nave S
FAU - Pedersen, Ragnor
AU  - Pedersen R
FAU - Reich, Hermine
AU  - Reich H
FAU - Robinson, Tobin
AU  - Robinson T
FAU - Ruocco, Silvia
AU  - Ruocco S
FAU - Santos, Miguel
AU  - Santos M
FAU - Scarlato, Alessia Pia
AU  - Scarlato AP
FAU - Theobald, Anne
AU  - Theobald A
FAU - Verani, Alessia
AU  - Verani A
LA  - eng
PT  - Journal Article
DEP - 20221118
PL  - United States
TA  - EFSA J
JT  - EFSA journal. European Food Safety Authority
JID - 101642076
PMC - PMC9672883
OTO - NOTNLM
OT  - CXL
OT  - MRLs
OT  - consumer risk assessment
OT  - haloxyfop-P
OT  - import tolerance
OT  - regulation (EC) No 396/2005
OT  - toxicological reference values
EDAT- 2022/11/24 06:00
MHDA- 2022/11/24 06:01
PMCR- 2022/11/18
CRDT- 2022/11/23 02:15
PHST- 2022/11/23 02:15 [entrez]
PHST- 2022/11/24 06:00 [pubmed]
PHST- 2022/11/24 06:01 [medline]
PHST- 2022/11/18 00:00 [pmc-release]
AID - EFS27658 [pii]
AID - 10.2903/j.efsa.2022.7658 [doi]
PST - epublish
SO  - EFSA J. 2022 Nov 18;20(11):e07658. doi: 10.2903/j.efsa.2022.7658. eCollection 
      2022 Nov.