PMID- 36419784
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221125
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 9
DP  - 2022
TI  - Effect of Wu Qin Xi exercises on pain and function in people with knee 
      osteoarthritis: A systematic review and meta-analysis.
PG  - 979207
LID - 10.3389/fmed.2022.979207 [doi]
LID - 979207
AB  - BACKGROUND: As a chronic disease that affects the whole world, there is no 
      definite treatment for knee osteoarthritis (KOA). Wu Qin Xi (WQX) is still in 
      preliminary exploration as a traditional Chinese exercise in the treatment of 
      osteoarthritis of the knee. The purpose of this study was to conduct a 
      meta-analysis of previous studies and to investigate the efficacy of the WQX 
      exercises on pain and function in patients with KOA. METHODS: We searched six 
      databases (Pubmed, Embase, Cochrane Library, Wanfang, CQVIP, and CNKI) for 
      articles on WQX for KOA up to May 10, 2022. Literature search, study selection, 
      data extraction, and quality evaluation were performed by two independent 
      authors. In terms of statistical results, we presented mean differences (MD), 95% 
      CI, and I (2) to show heterogeneity, and, based on that, we chose either a random 
      effects model or a fixed effects model. RESULTS: Seven studies were selected for 
      inclusion in this meta-analysis. The WQX intervention group showed statistical 
      differences for both the total Western Ontario and McMaster Universities 
      Osteoarthritis Index (WOMAC) score and its various bylaws, the Visual Analogue 
      Score (VAS), and the presence of general functional exercise in the control 
      group. We also demonstrated the clinically meaningful efficacy of WQX treatment 
      by calculating minimum clinical importance difference (MCID) values that met the 
      MCID values on the WOMAC score. A sensitivity analysis was also performed in this 
      study by subgroup analysis for greater heterogeneity, and it was inferred that 
      the difference in follow-up time was a likely source of heterogeneity. 
      CONCLUSION: Despite some limitations, the current study showed a definite effect 
      of WQX in improving pain symptoms and joint function in patients with KOA. 
      SYSTEMATIC REVIEW REGISTRATION: https://www.crd.york.ac.uk/prospero/, identifier: 
      CRD42022332209.
CI  - Copyright (c) 2022 Guo, Peng, Hu, Guo, Dai and Li.
FAU - Guo, Jiale
AU  - Guo J
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
FAU - Peng, Caiju
AU  - Peng C
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
FAU - Hu, Ziyan
AU  - Hu Z
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
FAU - Guo, Liangliang
AU  - Guo L
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
FAU - Dai, Ru
AU  - Dai R
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
FAU - Li, Yehai
AU  - Li Y
AD  - Department of Orthopedics, Chaohu Hospital of Anhui Medical University, Hefei, 
      China.
LA  - eng
PT  - Systematic Review
DEP - 20221107
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC9676488
OTO - NOTNLM
OT  - Chinese traditional medicine
OT  - Wu Qin Xi
OT  - function
OT  - knee osteoarthritis
OT  - meta-analysis
OT  - pain
OT  - qigong
OT  - systematic review
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/11/25 06:00
MHDA- 2022/11/25 06:01
PMCR- 2022/11/07
CRDT- 2022/11/24 02:23
PHST- 2022/06/27 00:00 [received]
PHST- 2022/09/01 00:00 [accepted]
PHST- 2022/11/24 02:23 [entrez]
PHST- 2022/11/25 06:00 [pubmed]
PHST- 2022/11/25 06:01 [medline]
PHST- 2022/11/07 00:00 [pmc-release]
AID - 10.3389/fmed.2022.979207 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2022 Nov 7;9:979207. doi: 10.3389/fmed.2022.979207. 
      eCollection 2022.