PMID- 36422074
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221129
IS  - 2075-4426 (Print)
IS  - 2075-4426 (Electronic)
IS  - 2075-4426 (Linking)
VI  - 12
IP  - 11
DP  - 2022 Nov 13
TI  - Adverse Effects in Patients with Intellectual and Developmental Disabilities 
      Hospitalized at the University Clinical Hospital.
LID - 10.3390/jpm12111898 [doi]
LID - 1898
AB  - (1) Background: Providing the patient with the health care they need in a 
      personalized and appropriate manner and without adverse effects (AEs) is a part 
      of quality of care and patient safety. The aim of this applied research project 
      was the assessment of AEs as a clinical risk in patients with high social 
      vulnerability such as persons with intellectual and developmental disabilities 
      (PwIDD). (2) Methods: A retrospective epidemiological cohort study was performed 
      on exposed and unexposed groups (the control group) in order to estimate the 
      incidence of AEs in PwIDDs and assess their importance for this category of 
      patients. (3) Results: AEs were observed with a frequency of 30.4% (95% CI) in 
      the PwIDD exposed group, with significant differences to the unexposed group (p = 
      0.009). No differences were observed with regards to gender. Age was as a marker 
      of care risk, with the highest incidence of AEs in the group of 60-69 years. (4) 
      Conclusions: PwIDDs have a high risk of suffering AEs while receiving health care 
      assistance due to their high social and clinical vulnerability. Health care 
      practitioners must therefore be aware of these results and keep these 
      observations in mind in order to carry out personalized, preventive, competent, 
      effective, and safe medical care.
FAU - Alonso-Sardon, Montserrat
AU  - Alonso-Sardon M
AUID- ORCID: 0000-0003-1829-5858
AD  - Department of Biomedical and Diagnostic Sciences, School of Medicine, University 
      of Salamanca, 37008 Salamanca, Spain.
FAU - Saez-Lorenzo, Maria
AU  - Saez-Lorenzo M
AD  - Pharmacological Treatments in Persons with Disabilities, School of Medicine, 
      University of Salamanca, 37008 Salamanca, Spain.
FAU - Chamorro, Antonio Javier
AU  - Chamorro AJ
AUID- ORCID: 0000-0002-2345-2873
AD  - Disability and Prevalent Chronic Diseases, Adjunct of Internal Medicine, Faculty 
      of Medicine, University Hospital of Salamanca (SACYL), 37008 Salamanca, Spain.
FAU - Fernandez-Martin, Luz Celia
AU  - Fernandez-Martin LC
AD  - Expert in Social and Communication Skills in Persons with Disabilities, School of 
      Phicology, University of Salamanca, 37008 Salamanca, Spain.
FAU - Iglesias-de-Sena, Helena
AU  - Iglesias-de-Sena H
AD  - Pharmacological Treatments in Persons with Disabilities, School of Medicine, 
      University of Salamanca, 37008 Salamanca, Spain.
FAU - Gonzalez-Nunez, Veronica
AU  - Gonzalez-Nunez V
AUID- ORCID: 0000-0002-9410-5510
AD  - Department of Biochemistry and Molecular Biology, Faculty of Medicine, Institute 
      of Biomedical Research of Salamanca (IBSAL), University of Salamanca, 37008 
      Salamanca, Spain.
AD  - Instituto de Neurociencias de Castilla y Leon (INCyL), University of Salamanca, 
      37008 Salamanca, Spain.
FAU - Santos-Sanchez, Jose Angel
AU  - Santos-Sanchez JA
AUID- ORCID: 0000-0002-0026-4474
AD  - Specialist in Traumatology and Radiodiagnosis in Persons with Disabilities, 
      School of Medicine, University of Salamanca, 37008 Salamanca, Spain.
FAU - Carbonell, Cristina
AU  - Carbonell C
AD  - Specialist in Infectious Diseases, Salamanca University Hospital, 37007 
      Salamanca, Spain.
FAU - Lorenzo-Gomez, Maria Fernanda
AU  - Lorenzo-Gomez MF
AD  - Disability and Incontinence, Faculty of Medicine, University of Salamanca 
      Clinical Hospital (SACYL), 37007 Salamanca, Spain.
FAU - Miron-Canelo, Jose Antonio
AU  - Miron-Canelo JA
AUID- ORCID: 0000-0002-7483-2761
AD  - Preventive Medicine and Public Health, Institute of Biomedical Research of 
      Salamanca (IBSAL), 37007 Salamanca, Spain.
LA  - eng
PT  - Journal Article
DEP - 20221113
PL  - Switzerland
TA  - J Pers Med
JT  - Journal of personalized medicine
JID - 101602269
PMC - PMC9698866
OTO - NOTNLM
OT  - adverse effects
OT  - care quality
OT  - patient safety
OT  - persons with intellectual and developmental disabilities
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2022/11/25 06:00
MHDA- 2022/11/25 06:01
PMCR- 2022/11/13
CRDT- 2022/11/24 10:24
PHST- 2022/09/28 00:00 [received]
PHST- 2022/10/22 00:00 [revised]
PHST- 2022/11/07 00:00 [accepted]
PHST- 2022/11/24 10:24 [entrez]
PHST- 2022/11/25 06:00 [pubmed]
PHST- 2022/11/25 06:01 [medline]
PHST- 2022/11/13 00:00 [pmc-release]
AID - jpm12111898 [pii]
AID - jpm-12-01898 [pii]
AID - 10.3390/jpm12111898 [doi]
PST - epublish
SO  - J Pers Med. 2022 Nov 13;12(11):1898. doi: 10.3390/jpm12111898.