PMID- 36424021
OWN - NLM
STAT- MEDLINE
DCOM- 20221128
LR  - 20230201
IS  - 1558-3163 (Electronic)
IS  - 0889-857X (Linking)
VI  - 49
IP  - 1
DP  - 2023 Feb
TI  - Lessons from Cardiac and Vascular Biopsies from Patients with and without 
      Inflammatory Rheumatic Diseases.
PG  - 129-150
LID - S0889-857X(22)00068-0 [pii]
LID - 10.1016/j.rdc.2022.07.005 [doi]
AB  - Feiring Heart Biopsy Study enables searching for potential pathogenetic 
      mechanisms, therapeutic targets, and biomarkers through the assessment of 
      clinical data and multiple blood and tissue samples from patients with and 
      without inflammatory rheumatic diseases (IRDs), undergoing coronary artery bypass 
      grafting. Some of our findings, for example, more inflammation (including the 
      presence of immune cells and expression of proinflammatory cytokines) in vessels 
      and the heart, and the presence of certain bacteria and autoantigens in vessels, 
      could contribute to the increased risk of ischemia, aneurysms, and/or cardiac 
      dysfunction in IRDs. Furthermore, some of the detected factors could be involved 
      in the pathomechanisms of these conditions in general.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Hollan, Ivana
AU  - Hollan I
AD  - Department of Health Sciences, Norwegian University of Science and Technology 
      Teknologivegen 22, 2815 Gjovik, Norway. Electronic address: 
      ivana.hollan@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Rheum Dis Clin North Am
JT  - Rheumatic diseases clinics of North America
JID - 8708093
RN  - 0 (Cytokines)
SB  - IM
MH  - Humans
MH  - Biopsy
MH  - *Inflammation
MH  - Cytokines
MH  - *Rheumatic Diseases
OTO - NOTNLM
OT  - Cardiovascular disease
OT  - Immune system
OT  - Infections
OT  - Inflammation
OT  - Rheumatic diseases
EDAT- 2022/11/25 06:00
MHDA- 2022/11/29 06:00
CRDT- 2022/11/24 21:04
PHST- 2022/11/24 21:04 [entrez]
PHST- 2022/11/25 06:00 [pubmed]
PHST- 2022/11/29 06:00 [medline]
AID - S0889-857X(22)00068-0 [pii]
AID - 10.1016/j.rdc.2022.07.005 [doi]
PST - ppublish
SO  - Rheum Dis Clin North Am. 2023 Feb;49(1):129-150. doi: 10.1016/j.rdc.2022.07.005.