PMID- 36425088 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231003 IS - 2574-2167 (Electronic) IS - 2574-2167 (Linking) VI - 5 IP - 3 DP - 2022 Sep TI - A systematic review and meta-analysis of anesthesia type on hip fracture post-surgery outcomes. PG - e204 LID - 10.1097/OI9.0000000000000204 [doi] LID - e204 AB - OBJECTIVE: To compare technical, clinical, and safety outcomes among hip fracture patients treated with procedures supplemented by general anesthesia (GA) or spinal/regional anesthesia (S/R). DATA SOURCES: We searched for original studies on PubMed, Ovid MEDLINE, Ovid Embase, and Cochrane databases. STUDY SELECTION: Studies that reported clinical outcomes in patients that underwent hip fracture surgery, had available data on type of anesthesia administered, and clinical follow-up data were selected for data extraction. DATA EXTRACTION: The primary outcomes of interest were odds of mortality, including in-hospital, 30-day, 90-day, and 1-year mortality. Various adverse events (AEs) were also compared. DATA SYNTHESIS: Twenty-eight studies met our selection criteria, including 190,394 patients. A total of 107,314 (56.4%) patients were treated with procedures involving GA while 83,080 (43.6%) were treated with procedures involving S/R. There was no difference in 30-day or >1-year mortality rates between the GA and SR groups; however, compared to S/R group, the GA group had a significantly higher odds of in-hospital (P = .004) and 90-day mortality (P = .004). There was no difference in odds of adverse events between the GA and the S/R group. CONCLUSIONS: Patients administered S/R for hip fracture procedures demonstrate lower risk of in-hospital mortality and 90-day mortality compared to patients administered GA. LEVEL OF EVIDENCE: Therapeutic level III. CI - Copyright (c) 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Orthopaedic Trauma Association. FAU - Leibold, Christopher AU - Leibold C AD - Department of Orthopedic Surgery, Mercy Health St. Vincent Medical Center. FAU - Falbo, Ryan AU - Falbo R AD - Department of Orthopedic Surgery, Mercy Health St. Vincent Medical Center. FAU - Gupta, Anil AU - Gupta A AD - Toledo Orthopaedic Surgeons, Toledo, OH. FAU - Miller, Richard AU - Miller R AD - Department of Orthopedic Surgery, Mercy Health St. Vincent Medical Center. FAU - Pederson, John M AU - Pederson JM AD - Superior Medical Experts, Minneapolis, MN, USA. FAU - Malpe, Manashree AU - Malpe M AD - Superior Medical Experts, Minneapolis, MN, USA. LA - eng PT - Journal Article DEP - 20220804 PL - United States TA - OTA Int JT - OTA international : the open access journal of orthopaedic trauma JID - 101770383 PMC - PMC9580260 OTO - NOTNLM OT - anesthesia OT - femoral neck fracture OT - hip fracture COIS- The authors have no conflicts of interest to disclose. EDAT- 2022/11/26 06:00 MHDA- 2022/11/26 06:01 PMCR- 2022/08/04 CRDT- 2022/11/25 02:38 PHST- 2021/07/25 00:00 [received] PHST- 2022/03/15 00:00 [accepted] PHST- 2022/11/25 02:38 [entrez] PHST- 2022/11/26 06:00 [pubmed] PHST- 2022/11/26 06:01 [medline] PHST- 2022/08/04 00:00 [pmc-release] AID - OTAI-D-21-00045 [pii] AID - 10.1097/OI9.0000000000000204 [doi] PST - epublish SO - OTA Int. 2022 Aug 4;5(3):e204. doi: 10.1097/OI9.0000000000000204. eCollection 2022 Sep.