PMID- 36439280
OWN - NLM
STAT- MEDLINE
DCOM- 20221129
LR  - 20221129
IS  - 1661-8564 (Electronic)
IS  - 1661-8556 (Print)
IS  - 1661-8556 (Linking)
VI  - 67
DP  - 2022
TI  - High Prevalence of Helicobacter pylori Infection Among School-Aged Children in Ho 
      Chi Minh City, VietNam.
PG  - 1605354
LID - 10.3389/ijph.2022.1605354 [doi]
LID - 1605354
AB  - Objectives: There is no study on Helicobacter pylori (H. pylori) infection in 
      pupils of Ho Chi Minh city (HCMC), the most overcrowded city in Vietnam. 
      Therefore, the aim of this study was to estimate the prevalence of H. pylori and 
      its geographical spread among school-aged children. Methods: A school-based 
      cross-sectional study was conducted among 1854 pupils across 24 districts of HCMC 
      in 2019. Multiple-stage sampling method was used to enroll pupils. We built a 
      four-points index for geographical division based on population density and 
      employees density to evaluate the link between H. pylori and crowded level. Stool 
      samples were analyzed by monoclonal enzyme-immunoassay stool antigen-test to 
      assess the infection status. Logistic regression was performed to assess possible 
      factors related to H. pylori infection. Results: The overall prevalence of H. 
      pylori was 87.7%. There was a linear increasing trend in the infection rate (p < 
      0.001) across the 4-points index of HCMC and this trend maintained within both 
      age and gender subgroups (p = 0.02). Conclusion: Prevalence of H. pylori was high 
      and it increased with population density or employees density. Therefore, it is 
      crucial to plan and implement the reduction of H. pylori infection programs by 
      targeting the highly concentrated population areas of HCMC.
CI  - Copyright (c) 2022 Che, Nguyen, Ngo, Nguyen, Vo, Ngo, Truong, Bontems, Robert and 
      Nguyen.
FAU - Che, Thai Hoang
AU  - Che TH
AD  - Department of Biostatistics and Informatics, Faculty of Public Health, Pham Ngoc 
      Thach University of Medicine, Ho Chi Minh City, Vietnam.
AD  - Pole Epidemiologie et Biostatistique (EPID), Institut de Recherche Experimentale 
      et Clinique (IREC), Faculte de Sante Publique (FSP), Universite Catholique de 
      Louvain, Brussels, Belgium.
FAU - Nguyen, Tu Cam
AU  - Nguyen TC
AD  - Department of Gastroenterology and Hepatology, City Children's Hospital, Ho Chi 
      Minh, Vietnam.
FAU - Ngo, Dung Thi Thuy
AU  - Ngo DTT
AD  - Department of Epidemiology, Pham Ngoc Thach University of Medicine, Ho Chi Minh 
      City, Vietnam.
FAU - Nguyen, Hiep Thanh
AU  - Nguyen HT
AD  - Faculty of Public Health, Pham Ngoc Thach University of Medicine, Ho Chi Minh 
      City, Vietnam.
FAU - Vo, Khang Tan
AU  - Vo KT
AD  - Department of Physiology, Pathophysiology and Immunology, Pham Ngoc Thach 
      University of Medicine, Ho Chi Minh City, Vietnam.
FAU - Ngo, Xuan Minh
AU  - Ngo XM
AD  - Faculty of Medicine, University of Medicine Pham Ngoc Thach, Ho Chi Minh City, 
      Vietnam.
FAU - Truong, Dinh Quang
AU  - Truong DQ
AD  - Department of Surgery, City Children's Hospital, Ho Chi Minh, Vietnam.
FAU - Bontems, Patrick
AU  - Bontems P
AD  - Gastroenterology, Hopital Universitaire des Enfants Reine Fabiola, Universite 
      libre de Bruxelles, Brussels, Belgium.
FAU - Robert, Annie
AU  - Robert A
AD  - Pole Epidemiologie et Biostatistique (EPID), Institut de Recherche Experimentale 
      et Clinique (IREC), Faculte de Sante Publique (FSP), Universite Catholique de 
      Louvain, Brussels, Belgium.
FAU - Nguyen, Phuong Ngoc Van
AU  - Nguyen PNV
AD  - Department of Biostatistics and Informatics, Faculty of Public Health, Pham Ngoc 
      Thach University of Medicine, Ho Chi Minh City, Vietnam.
LA  - eng
PT  - Journal Article
DEP - 20221110
PL  - Switzerland
TA  - Int J Public Health
JT  - International journal of public health
JID - 101304551
SB  - IM
MH  - Child
MH  - Humans
MH  - *Helicobacter Infections/epidemiology
MH  - *Helicobacter pylori
MH  - Prevalence
MH  - Cross-Sectional Studies
MH  - Vietnam/epidemiology
PMC - PMC9684168
OTO - NOTNLM
OT  - Helicobacter pylori
OT  - Ho Chi Minh City
OT  - Vietnam
OT  - prevalence
OT  - pupils
OT  - school-aged children
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/11/29 06:00
MHDA- 2022/11/30 06:00
PMCR- 2022/11/10
CRDT- 2022/11/28 04:34
PHST- 2022/08/30 00:00 [received]
PHST- 2022/10/31 00:00 [accepted]
PHST- 2022/11/28 04:34 [entrez]
PHST- 2022/11/29 06:00 [pubmed]
PHST- 2022/11/30 06:00 [medline]
PHST- 2022/11/10 00:00 [pmc-release]
AID - 1605354 [pii]
AID - 10.3389/ijph.2022.1605354 [doi]
PST - epublish
SO  - Int J Public Health. 2022 Nov 10;67:1605354. doi: 10.3389/ijph.2022.1605354. 
      eCollection 2022.