PMID- 36439957 OWN - NLM STAT- MEDLINE DCOM- 20221129 LR - 20221129 IS - 1748-6718 (Electronic) IS - 1748-670X (Print) IS - 1748-670X (Linking) VI - 2022 DP - 2022 TI - Hybrid Diagnosis Models for Autism Patients Based on Medical and Sociodemographic Features Using Machine Learning and Multicriteria Decision-Making (MCDM) Techniques: An Evaluation and Benchmarking Framework. PG - 9410222 LID - 10.1155/2022/9410222 [doi] LID - 9410222 AB - METHOD: The three-phase framework integrated the MCDM and ML to develop the diagnosis models and evaluate and benchmark the best. Firstly, the new ASD-dataset-combined medical tests and sociodemographic characteristic features is identified and preprocessed. Secondly, developing the hybrid diagnosis models using the intersection process between three FS techniques and five ML algorithms introduces 15 models. The selected medical tests and sociodemographic features from each FS technique are weighted before feeding the five ML algorithms using the fuzzy-weighted zero-inconsistency (FWZIC) method based on four psychiatry experts. Thirdly, (i) formulate a dynamic decision matrix for all developed models based on seven evaluation metrics, including classification accuracy, precision, F1 score, recall, test time, train time, and AUC. (ii) The fuzzy decision by opinion score method (FDOSM) is used to evaluate and benchmark the 15 models concerning the seven evaluation metrics. RESULTS: Results reveal that (i) the three FS techniques have obtained a size different from the others in the number of the selected features; the sets were 39, 38, and 41 out of 48 features. Each set has its weights constructed by FWIZC. Considered sociodemographic features have been mostly selected more than medical tests within FS techniques. (ii) The first three best hybrid models were "ReF-decision tree," "IG-decision tree," and "Chi(2)-decision tree," with score values 0.15714, 0.17539, and 0.29444. The best diagnosis model (ReF-decision tree) has obtained 0.4190, 0.0030, 0.9946, 0.9902, 0.9902, 0.9902, 0.9902, and 0.9951 for the C1=train time, C2=test time, C3=AUC, C4=CA, C5=F1 score, C6=precision, and C7=recall, respectively. The developed framework would be beneficial in advancing, accelerating, and selecting diagnosis tools in therapy with ASD. The selected model can identify severity as light, medium, or intense based on medical tests and sociodemographic weighted features. CI - Copyright (c) 2022 M. E. Alqaysi et al. FAU - Alqaysi, M E AU - Alqaysi ME AD - Informatics Institute for Postgraduate Studies (IIPS), Iraqi Commission for Computers and Informatics (ICCI), Baghdad, Iraq. AD - Department of Medical Instruments Engineering Techniques, Al-Farahidi University, Baghdad 10021, Iraq. FAU - Albahri, A S AU - Albahri AS AUID- ORCID: 0000-0003-3335-457X AD - Informatics Institute for Postgraduate Studies (IIPS), Iraqi Commission for Computers and Informatics (ICCI), Baghdad, Iraq. FAU - Hamid, Rula A AU - Hamid RA AD - College of Business Informatics, University of Information Technology and Communications (UOITC), Baghdad, Iraq. LA - eng PT - Journal Article DEP - 20221116 PL - United States TA - Comput Math Methods Med JT - Computational and mathematical methods in medicine JID - 101277751 SB - IM MH - Humans MH - *Benchmarking MH - *Autistic Disorder/diagnosis MH - Machine Learning MH - Algorithms PMC - PMC9683965 COIS- The authors declare that they have no conflicts of interest. EDAT- 2022/11/29 06:00 MHDA- 2022/11/30 06:00 PMCR- 2022/11/16 CRDT- 2022/11/28 04:47 PHST- 2022/08/19 00:00 [received] PHST- 2022/10/01 00:00 [revised] PHST- 2022/10/18 00:00 [accepted] PHST- 2022/11/28 04:47 [entrez] PHST- 2022/11/29 06:00 [pubmed] PHST- 2022/11/30 06:00 [medline] PHST- 2022/11/16 00:00 [pmc-release] AID - 10.1155/2022/9410222 [doi] PST - epublish SO - Comput Math Methods Med. 2022 Nov 16;2022:9410222. doi: 10.1155/2022/9410222. eCollection 2022.