PMID- 36452663 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231002 IS - 2231-3796 (Print) IS - 0973-7707 (Electronic) IS - 2231-3796 (Linking) VI - 74 IP - Suppl 2 DP - 2022 Oct TI - A Prospective Study of Audiological Manifestations in Patients of Allergic Rhinitis. PG - 1256-1261 LID - 10.1007/s12070-020-02343-5 [doi] AB - Allergic rhinitis is a type-I hypersensitivity reaction of the nasal mucosa, primarily mediated by immunoglobulin E (IgE) with complex etiological factors.Allergic rhinitis may involve the inner ear. The scientific basis for this is poorly understood. However, the inner ear has been found to demonstrate both cellular and humoral immunity, and the seat of immuno-activity appears to reside in the endolymphatic sac and duct. To assess the audiological profile of patients with allergic rhinitis. 100 Study group patients and 50 control group subjects underwent detailed audiological assessment. Present study revealed high frequency sensorineural hearing loss with prolongation of Wave I and shortened wave I-III and Wave I-V interpeak latencies on ABR and abnormal DPOAE findings, compared with controls which indicate inner ear involvement (cochlear pathology). Individuals with allergic rhinitis are more prone to hearing abnormalities which can be detected even before any symptoms of hearing impairment are present. However, the exact pathophysiology of inner ear damage in patients of airway allergy is poorly understood and therefore, additional studies in this area are required with a larger sample population to assess the benefits of hearing assessment in patients of allergic rhinitis for early detection of hearing loss. CI - (c) Association of Otolaryngologists of India 2021. FAU - Mahajan, Akriti AU - Mahajan A AD - Department of Otorhinolaryngology and H&N Surgery, GMC Jammu, Jammu, India. GRID: grid.413224.2. ISNI: 0000 0004 1800 4333 FAU - Manhas, Monica AU - Manhas M AD - Department of Physiology, GMC Jammu, Jammu, India. GRID: grid.413224.2. ISNI: 0000 0004 1800 4333 FAU - Kalsotra, Parmod AU - Kalsotra P AD - Department of Otorhinolaryngology and H&N Surgery, GMC Jammu, Jammu, India. GRID: grid.413224.2. ISNI: 0000 0004 1800 4333 FAU - Kalsotra, Gopika AU - Kalsotra G AD - Department of Otorhinolaryngology and H&N Surgery, GMC Jammu, Jammu, India. GRID: grid.413224.2. ISNI: 0000 0004 1800 4333 FAU - Gul, Naveed AU - Gul N AD - Department of Otorhinolaryngology and H&N Surgery, GMC Jammu, Jammu, India. GRID: grid.413224.2. ISNI: 0000 0004 1800 4333 LA - eng PT - Journal Article DEP - 20210107 PL - India TA - Indian J Otolaryngol Head Neck Surg JT - Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India JID - 9422551 PMC - PMC9701995 OTO - NOTNLM OT - Allergic rhinitis OT - BERA OT - DPOAE OT - OAE OT - PTA OT - TEOAE EDAT- 2022/12/02 06:00 MHDA- 2022/12/02 06:01 PMCR- 2023/10/01 CRDT- 2022/12/01 02:50 PHST- 2020/07/31 00:00 [received] PHST- 2020/12/15 00:00 [accepted] PHST- 2022/12/01 02:50 [entrez] PHST- 2022/12/02 06:00 [pubmed] PHST- 2022/12/02 06:01 [medline] PHST- 2023/10/01 00:00 [pmc-release] AID - 2343 [pii] AID - 10.1007/s12070-020-02343-5 [doi] PST - ppublish SO - Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1256-1261. doi: 10.1007/s12070-020-02343-5. Epub 2021 Jan 7.